Results 41 to 50 of about 156,509 (154)

Upper airway inflammatory diseases and bronchial hyperresponsiveness

Journal of Allergy and Clinical Immunology, 1988
Inflammatory processes of the upper airway may alter the responsiveness of the lower airway. For example, bronchial hyperresponsiveness may be seen in patients with allergic rhinitis. This could represent coexistent but unrecognized asthma, but also suggests that IgE-dependent inflammation may occur in the lower airway that can increase bronchial ...
openaire   +2 more sources

A translational view of airway epithelial dysfunction in COPD

European Respiratory Review
COPD is a heterogeneous, progressive inflammatory airway disease, with patients presenting with a wide variety of symptoms, comorbid conditions and underlying pathophysiology.
Christopher E. Brightling, Mona Bafadhel, MeiLan K. Han, Jean-Francois Papon, Klaus F. Rabe, Paola Rogliani, Dave Singh   +6 more
doaj   +1 more source

Human Cellular Models for the Investigation of Lung Inflammation and Mucus Production in Cystic Fibrosis

Analytical Cellular Pathology, 2018
Chronic inflammation, oxidative stress, mucus plugging, airway remodeling, and respiratory infections are the hallmarks of the cystic fibrosis (CF) lung disease.
Stefano Castellani, Sante Di Gioia, Lorena di Toma, Massimo Conese   +3 more
doaj   +1 more source

IL-18 induces airway hyperresponsiveness and pulmonary inflammation via CD4+ T cell and IL-13. [PDF]

PLoS ONE, 2013
IL-18 plays a key role in the pathogenesis of pulmonary inflammatory diseases including pulmonary infection, pulmonary fibrosis, lung injury and chronic obstructive pulmonary disease (COPD).
Masanori Sawada, Tomotaka Kawayama, Haruki Imaoka, Yuki Sakazaki, Hanako Oda, Shin-ichi Takenaka, Yoichiro Kaku, Koichi Azuma, Morihiro Tajiri, Nobutaka Edakuni, Masaki Okamoto, Seiya Kato, Tomoaki Hoshino   +12 more
doaj   +1 more source

Respiratory Viral Infections in Exacerbation of Chronic Airway Inflammatory Diseases: Novel Mechanisms and Insights From the Upper Airway Epithelium

Frontiers in Cell and Developmental Biology, 2020
Respiratory virus infection is one of the major sources of exacerbation of chronic airway inflammatory diseases. These exacerbations are associated with high morbidity and even mortality worldwide. The current understanding on viral-induced exacerbations
Kai Sen Tan, Rachel Liyu Lim, Jing Liu, Hsiao Hui Ong, Vivian Jiayi Tan, Hui Fang Lim, Hui Fang Lim, Kian Fan Chung, Ian M. Adcock, Vincent T. Chow, De Yun Wang   +10 more
doaj   +1 more source

Inflammatory airway diseases and clinical allergy [PDF]

European Respiratory Journal, 2010
Assembly 5 of the European Respiratory Society (ERS) is the Inflammatory Airway Diseases and Clinical Allergy Assembly and consists of three Scientific Groups: 1) Airway Pharmacology and Treatment; 2) Monitoring Airway Diseases; and 3) Allergy and Immunology.
G F, Joos, P J, Barnes
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A liver-X-receptor ligand, T0901317, attenuates IgE production and airway remodeling in chronic asthma model of mice.

PLoS ONE, 2014
The liver-X-receptors have shown anti-inflammatory ability in several animal models of respiratory disease. Our purpose is to investigate the effect of LXR ligand in allergen-induced airway remodeling in mice.
Ying Shi, Xiantao Xu, Yan Tan, Shan Mao, Surong Fang, Wei Gu   +5 more
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Therapeutic potential of elafin in airway inflammatory disease

European Journal of Inflammation
Elafin, which is derived from trappin-2 or pre-elafin by proteolysis, is an endogenous serine protease inhibitor with a low molecular weight. Its inhibitory activity is dependent on anchoring to the extracellular matrix by forming covalent bonds with its
Mingxin He, Yalou Yang, Yanyan Li, Xiangdong Zhou, Li Xu, Ziwei Zhang, Hua Zhang, Qi Li   +7 more
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Protective Role of Nuclear Factor Erythroid 2-Related Factor 2 Against Respiratory Syncytial Virus and Human Metapneumovirus Infections

Frontiers in Immunology, 2018
The pathogenesis of respiratory syncytial virus (RSV) infections is characterized by lower airway obstruction driven at great extent by the exuberant production of inflammatory cytokines.
Teodora Ivanciuc, Elena Sbrana, Antonella Casola, Antonella Casola, Antonella Casola, Antonella Casola, Roberto P. Garofalo, Roberto P. Garofalo, Roberto P. Garofalo, Roberto P. Garofalo   +9 more
doaj   +1 more source

Asthma: where is it going?

Brazilian Journal of Medical and Biological Research, 2008
Asthma is characterized by reversible airway obstruction, airway hyperresponsiveness, and airway inflammation. Although our understanding of its pathophysiological mechanisms continues to evolve, the relative contributions of airway hyperresponsiveness ...
D.S. Faffe
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