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Inflammatory Bowel Disease [PDF]

New England Journal of Medicine, 2009
Inflammatory bowel diseases (IBDs) encompass ulcerative colitis, Crohn's disease, and indeterminate colitis, all of which are characterized by remission and exacerbation of gastrointestinal symptoms, and a variety of extraintestinal manifestations including those affecting the oral cavity.
Clara, Abraham, Judy H, Cho
  +8 more sources

Inflammatory bowel disease [PDF]

BMJ, 2015
Scandinavian researchers have contributed to the present understanding of inflammatory bowel disease (IBD). Important epidemiological data and family risk factors have been reported from all the Nordic countries, original twin studies mainly from Denmark and Sweden, and relationships to cancer and surgery mostly from Sweden.
Ella, Mozdiak, John, O'Malley, Ramesh, Arasaradnam   +2 more
openaire   +5 more sources

Extracts of Feijoa Inhibit Toll-Like Receptor 2 Signaling and Activate Autophagy Implicating a Role in Dietary Control of IBD [PDF]

, 2015
Inflammatory bowel disease (IBD) is a heterogeneous chronic inflammatory disease affecting the gut with limited treatment success for its sufferers.
A Asea, A Scalbert, A Scalbert, AK Abbas, C Fiocchi, C Huebner, CH Seow, CN Serhan, D Del Rio, D Li, David M. Ojcius, DM Shin, DRE Ranoa, DW Hommes, FX Li, G Kroemer, Gareth Marlow, H Shapiro, H Sies, J da Silva Correia, JK Hou, L Bravo, L Frolova, L Zhao, Lynnette R Ferguson, M Fukata, M Yu, Nasef N Ahmed, Noha Ahmed Nasef, Penny Powell, PT Liu, Q Zhang, R Gonzalez, R Medzhitov, S Priego, Sunali Mehta, T Saitoh, T Sato, Tom Wileman, Y-Y Li   +39 more
core   +15 more sources

Inflammatory bowel disease [PDF]

Archives of Disease in Childhood, 2001
The epidemiology, aetiology, clinical features, diagnosis, and treatment of Crohn's disease and ulcerative colitis in children are reviewed, and areas for further research identified.
D J, Helper, D K, Rex
  +7 more sources

Novel Utility of Leucine-Rich Alpha-2-Glycoprotein as a Biomarker in Ulcerative Colitis: A Predictor of Endoscopic Remission Independent of Symptoms

Inflammatory Intestinal Diseases, 2023
Introduction: Leucine-rich alpha-2-glycoprotein (LRG) is a potential biomarker for disease activity and reflects mucosal healing in patients with ulcerative colitis (UC).
Tomoyuki Hayashi, Kazuya Kitamura, Masaaki Usami, Masaki Miyazawa, Masaki Nishitani, Akihiro Dejima, Makoto Yamamoto, Shotaro Kawase, Masaya Funaki, Noriaki Orita, Hidetoshi Nakagawa, Koki Morita, Noriho Iida, Akihiro Seki, Kouki Nio, Hidenori Kido, Hideo Takayama, Yuta Takeuchi, Shinya Yamada, Hajime Takatori, Mari Shimada, Hiroto Saito, Daisuke Yamamoto, Tadashi Toyama, Taro Yamashita   +24 more
doaj   +1 more source

Inflammatory Bowel Disease [PDF]

Annual Review of Immunology, 2010
Insights into inflammatory bowel disease (IBD) are advancing rapidly owing to immunologic investigations of a plethora of animal models of intestinal inflammation, ground-breaking advances in the interrogation of diseases that are inherited as complex genetic traits, and the development of culture-independent methods to define the composition of the ...
Arthur, Kaser, Sebastian, Zeissig, Richard S, Blumberg   +2 more
openaire   +5 more sources

Endoplasmic Reticulum Stress in Colonic Mucosa of Ulcerative Colitis Patients Is Mediated by PERK and IRE1 Pathway Activation

Mediators of Inflammation, 2022
Ulcerative colitis (UC) is characterized by a chronic overproduction of proinflammatory cytokines. During an acute phase, the endoplasmic reticulum (ER) is overloaded and the protein folding process is impaired, a condition named ER stress.
Bruno Lima Rodrigues, Isabella Dotti, Lívia Bitencourt Pascoal, Joseane Morari, Miriam Esteller, Andressa Coope, Maria de Lourdes Setsuko Ayrizono, Azucena Salas, Raquel Franco Leal   +8 more
doaj   +1 more source

Impact of the body mass index on the retention of the anorectal mucosa after double-stapled ileal pouch-anal anastomosis for ulcerative colitis

BMC Gastroenterology, 2023
Background Double-stapled ileal pouch-anal anastomosis (DS-IPAA) is easy to construct and has a good functional outcome in patients with ulcerative colitis (UC). However, retention of the anorectal mucosa may lead to a subsequent risk of inflammation and
Hideaki Kimura, Kenichiro Toritani, Reiko Kunisaki, Kenji Tatsumi, Kazutaka Koganei, Akira Sugita, Itaru Endo   +6 more
doaj   +1 more source

Microbial imbalance in inflammatory bowel disease patients at different taxonomic levels [PDF]

, 2020
Background Inflammatory bowel disease (IBD), is a debilitating group of chronic diseases including Crohn’s Disease (CD) and ulcerative colitis (UC), which causes inflammation of the gut and affects millions of people worldwide.
Alam, Mohammad T., Amos, Gregory C. A., Arasaradnam, Ramesh P., Murch, Simon, Murphy, Andrew, Wellington, E. M. H.   +5 more
core   +1 more source

Serum antibodies in first-degree relatives of patients with IBD: A marker of disease susceptibility? A follow-up pilot-study after 7 years [PDF]

, 2005
Introduction: Various disease-specific serum antibodies were described in patients with inflammatory bowel disease and their yet healthy first-degree relatives.
H.P. Török, J. Glas, H.C. Hollay, R. Gruber, M. Osthoff, L. Tonenchi, C. Brückl, T. Mussack, M. Folwaczny, C. Folwaczny, Glas J, Quinton JF, Ruemmele FM, Cambridge G, Colombel JF, Shanahan F, Hoffman IE, Torok HP, Seibold F, Folwaczny C, Folwaczny C, Folwaczny C, Seibold F, Shanahan F, Folwaczny C, Bansi DS, Klebl FH, Klebl FH, Torok HP, Lombardi G   +29 more
core   +5 more sources