Results 1 to 10 of about 1,342,022 (369)

Extracts of Feijoa Inhibit Toll-Like Receptor 2 Signaling and Activate Autophagy Implicating a Role in Dietary Control of IBD [PDF]

, 2015
Inflammatory bowel disease (IBD) is a heterogeneous chronic inflammatory disease affecting the gut with limited treatment success for its sufferers.
A Asea, A Scalbert, A Scalbert, AK Abbas, C Fiocchi, C Huebner, CH Seow, CN Serhan, D Del Rio, D Li, David M. Ojcius, DM Shin, DRE Ranoa, DW Hommes, FX Li, G Kroemer, Gareth Marlow, H Shapiro, H Sies, J da Silva Correia, JK Hou, L Bravo, L Frolova, L Zhao, Lynnette R Ferguson, M Fukata, M Yu, Nasef N Ahmed, Noha Ahmed Nasef, Penny Powell, PT Liu, Q Zhang, R Gonzalez, R Medzhitov, S Priego, Sunali Mehta, T Saitoh, T Sato, Tom Wileman, Y-Y Li   +39 more
core   +17 more sources

Novel Utility of Leucine-Rich Alpha-2-Glycoprotein as a Biomarker in Ulcerative Colitis: A Predictor of Endoscopic Remission Independent of Symptoms

Inflammatory Intestinal Diseases, 2023
Introduction: Leucine-rich alpha-2-glycoprotein (LRG) is a potential biomarker for disease activity and reflects mucosal healing in patients with ulcerative colitis (UC).
Tomoyuki Hayashi, Kazuya Kitamura, Masaaki Usami, Masaki Miyazawa, Masaki Nishitani, Akihiro Dejima, Makoto Yamamoto, Shotaro Kawase, Masaya Funaki, Noriaki Orita, Hidetoshi Nakagawa, Koki Morita, Noriho Iida, Akihiro Seki, Kouki Nio, Hidenori Kido, Hideo Takayama, Yuta Takeuchi, Shinya Yamada, Hajime Takatori, Mari Shimada, Hiroto Saito, Daisuke Yamamoto, Tadashi Toyama, Taro Yamashita   +24 more
doaj   +1 more source

Pathophysiology of Inflammatory Bowel Disease: Innate Immune System

International Journal of Molecular Sciences, 2023
Inflammatory bowel disease (IBD), comprising Crohn’s disease (CD) and ulcerative colitis (UC), is a heterogeneous state of chronic intestinal inflammation with no exact known cause.
Angela Sáez, Beatriz Herrero-Fernández, Raquel Gomez-Bris, Héctor F Sánchez-Martínez, J. González-Granado   +4 more
semanticscholar   +1 more source

Endoplasmic Reticulum Stress in Colonic Mucosa of Ulcerative Colitis Patients Is Mediated by PERK and IRE1 Pathway Activation

Mediators of Inflammation, 2022
Ulcerative colitis (UC) is characterized by a chronic overproduction of proinflammatory cytokines. During an acute phase, the endoplasmic reticulum (ER) is overloaded and the protein folding process is impaired, a condition named ER stress.
Bruno Lima Rodrigues, Isabella Dotti, Lívia Bitencourt Pascoal, Joseane Morari, Miriam Esteller, Andressa Coope, Maria de Lourdes Setsuko Ayrizono, Azucena Salas, Raquel Franco Leal   +8 more
doaj   +1 more source

Impact of the body mass index on the retention of the anorectal mucosa after double-stapled ileal pouch-anal anastomosis for ulcerative colitis

BMC Gastroenterology, 2023
Background Double-stapled ileal pouch-anal anastomosis (DS-IPAA) is easy to construct and has a good functional outcome in patients with ulcerative colitis (UC). However, retention of the anorectal mucosa may lead to a subsequent risk of inflammation and
Hideaki Kimura, Kenichiro Toritani, Reiko Kunisaki, Kenji Tatsumi, Kazutaka Koganei, Akira Sugita, Itaru Endo   +6 more
doaj   +1 more source

Microbial imbalance in inflammatory bowel disease patients at different taxonomic levels [PDF]

, 2020
Background Inflammatory bowel disease (IBD), is a debilitating group of chronic diseases including Crohn’s Disease (CD) and ulcerative colitis (UC), which causes inflammation of the gut and affects millions of people worldwide.
Alam, Mohammad T., Amos, Gregory C. A., Arasaradnam, Ramesh P., Murch, Simon, Murphy, Andrew, Wellington, E. M. H.   +5 more
core   +1 more source

STRIDE-II: An Update on the Selecting Therapeutic Targets in Inflammatory Bowel Disease (STRIDE) Initiative of the International Organization for the Study of IBD (IOIBD): Determining Therapeutic Goals for Treat-to-Target strategies in IBD.

Gastroenterology, 2020
BACKGROUND The Selecting Therapeutic Targets in Inflammatory Bowel Disease (STRIDE) initiative of the International Organization for the Study of Inflammatory Bowel Diseases (IOIBD) has proposed treatment-targets in 2015 for adult IBD patients.
D. Turner, A. Ricciuto, Ayanna E. Lewis, F. D'amico, J. Dhaliwal, A. Griffiths, D. Bettenworth, W. Sandborn, B. Sands, W. Reinisch, J. Schölmerich, W. Bemelman, S. Danese, J. Mary, D. Rubin, J. Colombel, L. Peyrin-Biroulet, I. Dotan, M. Abreu, A. Dignass   +19 more
semanticscholar   +1 more source

The role of Akkermansia muciniphila in inflammatory bowel disease: Current knowledge and perspectives

Frontiers in Immunology, 2023
Inflammatory bowel diseases, including Crohn’s disease and ulcerative colitis, is a chronic relapsing gastrointestinal inflammatory disease mediated by dysregulated immune responses to resident intestinal microbiota.
Mengyu Zheng, Ran Han, Yali Yuan, Yunqi Xing, Wenji Zhang, Zhongmei Sun, Yuyue Liu, Junxiang Li, Tangyou Mao   +8 more
semanticscholar   +1 more source

Serum antibodies in first-degree relatives of patients with IBD: A marker of disease susceptibility? A follow-up pilot-study after 7 years [PDF]

, 2005
Introduction: Various disease-specific serum antibodies were described in patients with inflammatory bowel disease and their yet healthy first-degree relatives.
H.P. Török, J. Glas, H.C. Hollay, R. Gruber, M. Osthoff, L. Tonenchi, C. Brückl, T. Mussack, M. Folwaczny, C. Folwaczny, Glas J, Quinton JF, Ruemmele FM, Cambridge G, Colombel JF, Shanahan F, Hoffman IE, Torok HP, Seibold F, Folwaczny C, Folwaczny C, Folwaczny C, Seibold F, Shanahan F, Folwaczny C, Bansi DS, Klebl FH, Klebl FH, Torok HP, Lombardi G   +29 more
core   +5 more sources

Clinicopathological and prognostic evaluations of anorectal cancer after fecal diversion for patients with Crohn’s disease

BMC Gastroenterology, 2021
Purpose Colorectum diversion with a proximal stoma is often the preferred surgical approach in patients with Crohn's disease-related anorectal lesions or refractory colitis.
Hirosuke Kuroki, Akira Sugita, Kazutaka Koganei, Kenji Tatsumi, Ryo Futatsuki, Eiichi Nakao, Nao Obara, Katsuhiko Arai   +7 more
doaj   +1 more source