Results 101 to 110 of about 1,259,702 (421)

The Bowel Microbiota and Inflammatory Bowel Diseases [PDF]

International Journal of Inflammation, 2010
The human bowel contains a large and biodiverse bacterial community known as the microbiota or microbiome. It seems likely that the microbiota, fractions of the microbiota, or specific species comprising the microbiota provide the antigenic fuel that drives the chronic immune inflammation of the bowel mucosa that is characteristic of Crohn's disease ...
openaire   +3 more sources

Current concept on the pathogenesis of inflammatory bowel disease-crosstalk between genetic and microbial factors: Pathogenic bacteria and altered bacterial sensing or changes in mucosal integrity take "toll"? [PDF]

, 2006
The pathogenesis of inflammatory bowel disease (IBD) is only partially understood. Various environmental and host (e.g. genetic-, epithelial-, immune and non-immune) factors are involved.
Fischer, Simon, Gál, István, Lakatos, László, Lakatos, Péter László, Papp, János   +4 more
core   +1 more source

Interplay of integrins and selectins in metastasis

Molecular Oncology, EarlyView.
Here we review the role of integrins and their interplay with selectins in metastasis. The efficacy of integrin‐targeted therapies may be reduced in tumors where metastasis relies heavily on selectins. In certain tumors, integrins and selectins exhibit a synergistic interaction during intraperitoneal dissemination.
Diana Maltseva, Ashot Nersisyan, Alexander Tonevitsky   +2 more
wiley   +1 more source

A Turing mechanism in order to explain the patchy nature of Crohn's disease [PDF]

arXiv, 2020
Crohn's disease is an inflammatory bowel disease (IBD) that is not well understood. In particular, unlike other IBDs, the inflamed parts of the intestine compromise deep layers of the tissue and are not continuous but separated and distributed through the whole gastrointestinal tract, displaying a patchy inflammatory pattern.
arxiv  

Inhibitor of DNA binding‐1 is a key regulator of cancer cell vasculogenic mimicry

Molecular Oncology, EarlyView.
Elevated expression of transcriptional regulator inhibitor of DNA binding 1 (ID1) promoted cancer cell‐mediated vasculogenic mimicry (VM) through regulation of pro‐angiogenic and pro‐cancerous genes (e.g. VE‐cadherin (CDH5), TIE2, MMP9, DKK1). Higher ID1 expression also increased metastases to the lung and the liver.
Emma J. Thompson, Emma L. Dorward, Kristyn Jurrius, Nathalie Nataren, Markus Tondl, Kay K. Myo Min, Michaelia P. Cockshell, Anahita Fouladzadeh, John Toubia, Mark DeNichilo, Delphine Merino, Claudine S. Bonder   +11 more
wiley   +1 more source

Medical management of inflammatory bowel disease [PDF]

, 1999
Patients who have recently been diagnosed as suffering from inflammatory bowel disease face two disturbing realities: firstly the true cause of the disease has not yet been defined and secondly the long term prognosis is unpredictable.
Pullicino, Edgar
core  

A Case Report of Multiple Aseptic Facial and Spinal Abscesses in a 45-Year-Old with Inflammatory Bowel Disease [PDF]

, 2016
INTRODUCTION Sterile abscess syndrome is a rarely described entity that is often associated with auto-inflammatory disorders. Although clinically similar to septic abscesses, sterile abscesses are known to be unaffected by antibiotic regimens and ...
Francis, MD, Gloria, Jackson, MD, Kristen, Niu, MD, Bolin, Zheng, MD, Matthew   +3 more
core   +2 more sources

The evolving understanding of histology as an endpoint in ulcerative colitis [PDF]

Intestinal Research
A therapeutic goal for patients with ulcerative colitis (UC) is deep remission including clinical remission and mucosal healing. Mucosal healing was previously defined by endoscopic appearance, but recent studies demonstrate that histological ...
Shintaro Akiyama, Yusuke Miyatani, David T. Rubin   +2 more
doaj   +1 more source

Regional Variation in Pregnancy Outcomes amongst Women in Inflammatory Bowel Disease: A Population-Based Cohort Study

Canadian Journal of Gastroenterology and Hepatology, 2021
Background. Women with inflammatory bowel disease (IBD) are at risk of certain pregnancy outcomes such as preterm delivery, infants small for gestational age (SGA), and Cesarean delivery.
Parul Tandon, Christina Diong, Rachel Y. Chong, Geoffrey C. Nguyen   +3 more
doaj   +1 more source

COVID-19 With Preexisting Hypercoagulability Digestive Disease

Frontiers in Medicine, 2021
The outbreak of coronavirus disease of 2019 (COVID-19) has become a global public health and economic crisis. The advent of hypercoagulability and thrombotic complications can substantially influence the prognosis of COVID-19 patients. In this review, we
Mingshan Jiang, Mingshan Jiang, Mingshan Jiang, Jingxi Mu, Jingxi Mu, Jingxi Mu, Silan Shen, Silan Shen, Silan Shen, Hu Zhang, Hu Zhang, Hu Zhang   +11 more
doaj   +1 more source