Results 121 to 130 of about 1,107,019 (331)

Microphysiological Systems of Lymphatics and Immune Organs

Advanced Healthcare Materials, EarlyView.
This review surveys recent progress in engineering lymphatic microenvironments and immune organoids within microphysiological systems, emphasizing innovative strategies to recreate the biochemical and biophysical complexity of native lymphatic tissues.
Ishita Jain, Ankur Singh, Andrés J. García   +2 more
wiley   +1 more source

Toll-like receptor 7 protects against intestinal inflammation and restricts the development of colonic tissue-resident memory CD8+ T cells

Frontiers in Immunology
IntroductionThe maintenance of intestinal homeostasis depends on a complex interaction between the immune system, intestinal epithelial barrier, and microbiota.
Hussein Hamade, Masato Tsuda, Naoki Oshima, Dalton T. Stamps, Michelle H. Wong, Jasmine T. Stamps, Lisa S. Thomas, Brenda C. Salumbides, Caroline Jin, Jordan S. Nunnelee, Deepti Dhall, Stephan R. Targan, Kathrin S. Michelsen, Kathrin S. Michelsen   +13 more
doaj   +1 more source

Development of a Synthetic 3D Platform for Compartmentalized Kidney In Vitro Disease Modeling

Advanced Healthcare Materials, EarlyView.
A fully synthetic, compartmentalized 3D kidney disease model is introduced. The kidney model combines a PEG‐based hydrogel matrix with anisotropic, enzymatically degradable rod‐shaped microgels to spatially arrange a triple co‐culture of key renal epithelial, endothelial, and fibroblast cells.
Ninon Möhl, Daphne Bouwens, Johanna Abele, Aline Hans, Tanja Topic, Daniel Günther, Jitske Jansen, Rafael Kramann, Laura De Laporte   +8 more
wiley   +1 more source

Progressive Insights into 3D Bioprinting for Corneal Tissue Restoration

Advanced Healthcare Materials, EarlyView.
This review explores the potential of 3D bioprinting to replicate the complex structure and function of the human cornea. It highlights key advances in bioink development, printing modalities, and in vivo performance, while addressing current challenges and emerging strategies. The review emphasizes bioprinting's promise to overcome donor shortages and
Ilayda Namli, Deepak Gupta, Yogendra Pratap Singh, Pallab Datta, Muhammad Rizwan, Mehmet Baykara, Ibrahim T. Ozbolat   +6 more
wiley   +1 more source

Inflammatory Bowel Diseases [PDF]

Visceral Medicine, 2019
Anton J. Kroesen, W Reindl
openaire   +3 more sources

Serum lysozyme in inflammatory bowel and coeliac disease. [PDF]

, 1976
Elias Mallas, J M Terry, P Asquith, W. T. Cooke   +3 more
openalex   +1 more source

Living Materials Approach for In Situ Bio‐Polymers Production Using Bacillus Paralicheniformis in Microneedles

Advanced Healthcare Materials, EarlyView.
Dissolvable microneedle (MN) device containing Bacillus paralicheniformis. The polymeric matrix encapsulates and protects the bacteria, preserving their viability while enabling in situ production and release of γ‐polyglutamic acid. The bacteria are delivered into the skin via 500 µm‐long microneedles, and remain detectable on the skin 24 h post ...
Caroline Hali Alperovitz, Noa Ben David, Adi Gross, Boaz Mizrahi   +3 more
wiley   +1 more source

Case report: Successful therapy with recombinant human vascular endostatin in an elderly man with colon telangiectasia and idiopathic thrombocytopenic purpura

Frontiers in Medicine
An 83-year-old male presented to our Digestive System Department with a 5-day history of severe gastrointestinal (GI) bleeding and a 14-year history of idiopathic thrombocytopenic purpura (ITP) with low platelet levels.
Yushan Wu, Yushan Wu, Yushan Wu, Yongbin Jia, Mingshan Jiang, Mingshan Jiang, Mingshan Jiang, Hu Zhang, Hu Zhang, Hu Zhang   +9 more
doaj   +1 more source

Strategies to Improve the Lipophilicity of Hydrophilic Macromolecular Drugs

Advanced Healthcare Materials, EarlyView.
Hydrophilic macromolecular drugs can be successfully lipidized by covalent attachment of lipids, by hydrophobic ion pairing with negatively or positively charged surfactants, and by dry or wet reverse micelle formation. Lipophilicity enhancement of hydrophilic macromolecules has several benefits including stability and bioavailability improvement ...
Sera Lindner, Stefan Keim, Soheil Haddadzadegan, Odile Fernandez Romero, Katrin Zöller, Gabriel Stern, Ilaria Cesi, Krum Kafedjiiski, Andreas Bernkop‐Schnürch   +8 more
wiley   +1 more source

Association of Inflammatory Bowel Disease and Large Vascular Lesions

, 1976
S Yassinger, Ray Adelman, David Cantor, Charles H. Halsted, Robert Bolt   +4 more
openalex   +1 more source