Journal of the Anus, Rectum and Colon, 2017 Objectives: Although the aetiology of pouchitis after restorative proctocolectomy in ulcerative colitis (UC) remains unknown, infliximab (IFX) is often effective for this condition. However, indicators and predictors of treatment efficacy remain unclear.
Motoi Uchino +7 more
doaj +1 more source
Tacrolimus for ulcerative colitis in children: a multicenter survey in Japan [PDF]
Intestinal Research, 2019 Background/Aims Tacrolimus is effective for refractory ulcerative colitis in adults, while data for children is sparse. We aimed to evaluate the effectiveness and safety of tacrolimus for induction and maintenance therapy in Japanese children with ...
Tadahiro Yanagi +14 more
doaj +1 more source
Inflammatory Intestinal Diseases, 2023 Introduction: Recently, fecal calprotectin has been identified and used as an assessment tool for the confirmation of disease activity in ulcerative colitis.
Motoi Uchino +5 more
doaj +1 more source
Clinical Features and Risk Factors of Autoimmune Liver Involvement in Pediatric Inflammatory Bowel Disease [PDF]
, 2016 OBJECTIVES:Autoimmune liver disease is reported in up to 7.8% of children with inflammatory bowel disease. A distinct inflammatory bowel disease phenotype has been suggested in adults and in small pediatric cohorts.
Alexopoulou +31 more
core +1 more source
Malignancies in Inflammatory Bowel Disease [PDF]
Digestion, 2020 <b><i>Background:</i></b> Inflammatory bowel disease (IBD) is a chronic inflammatory disorder, primarily of, but not restricted to, the gut. Association between IBD and cancer has been clearly established and is uniformly accepted.
Greuter, Thomas +4 more
openaire +6 more sources
The gut microbiota, bile acids and their correlation in primary sclerosing cholangitis associated with inflammatory bowel disease. [PDF]
, 2018 BACKGROUND: Patients with primary sclerosing cholangitis associated with inflammatory bowel disease (PSC-IBD) have a very high risk of developing colorectal neoplasia.
Bao, X +7 more
core +1 more source
Rectal-sparing type of ulcerative colitis predicts lack of response to pharmacotherapies
BMC Surgery, 2017 Background Ulcerative colitis (UC) is known as an immune disorder of the colon that generally involves the rectum, but an atypical distribution of inflamed mucosa has previously been noted in certain subtypes of UC, such as the rectal-sparing type (RST).
Yuki Horio +7 more
doaj +1 more source
Impact of comorbidities on anti-TNF alpha response and relapse in patients with inflammatory bowel disease: the VERNE study [PDF]
, 2020 Objective: To evaluate the impact of comorbidities and extraintestinal manifestations of inflammatory bowel disease on the response of patients with inflammatory bowel disease to antitumour necrosis factor alpha (anti-TNFalpha) therapy. Design: Data from
Aguas, Mariam +19 more
core +2 more sources
Interactions between species introduce spurious associations in microbiome studies [PDF]
2018. PLoS Comput Biol 14(1): e1005939, 2017 Microbiota contribute to many dimensions of host phenotype, including disease. To link specific microbes to specific phenotypes, microbiome-wide association studies compare microbial abundances between two groups of samples. Abundance differences, however, reflect not only direct associations with the phenotype, but also indirect effects due to ...
arxiv +1 more source
The Use of Oral Herbal Medicine (Hange-Shashin-To) in Patients with Pouchitis: A Pilot Study
Journal of the Anus, Rectum and Colon, 2018 Objectives: Hange-Shashin-To (HST), which is a combination of seven herbs, has previously been used in the treatment of inflammatory or ulcerative gut disease.
Hiroki Matsuoka +9 more
doaj +1 more source