Results 31 to 40 of about 1,107,019 (331)

Faecal calprotectin level for assessing endoscopic activity and predicting future clinical course in patients with moderately active ulcerative colitis undergoing granulomonocytapheresis: a prospective cohort study

open access: yesBMC Gastroenterology, 2018
Background Calprotectin is a stable neutrophil protein, which can be measured in faecal samples. The faecal level of calprotectin increases during disease activity in ulcerative colitis (UC).
Takahiro Shimoyama   +3 more
doaj   +1 more source

Review of the safety with biologics in inflammatory bowel disease

open access: yesJournal of IMIDs, 2022
Biologics have completely changed the treatment (and life) of patients with inflammatory bowel disease (IBD). After the first ones, anti-tumor necrosis factor (TNF) biologics, two new biologics, with other therapeutic targets, are now in routine use in ...
Andrea Pascual   +3 more
doaj   +1 more source

Metalloproteinases in Inflammatory Bowel Diseases

open access: yesJournal of Inflammation Research, 2021
Inflammatory bowel diseases (IBD) are chronic inflammatory diseases of the gastrointestinal tract, encompassing two main disorders: Crohn's disease (CD) and ulcerative colitis (UC). In both these pathologies, excessive and local immune response against luminal antigens promotes a pathological process leading to various degrees of gut damage.
Maronek M.   +5 more
openaire   +7 more sources

The Use of Oral Herbal Medicine (Hange-Shashin-To) in Patients with Pouchitis: A Pilot Study

open access: yesJournal of the Anus, Rectum and Colon, 2018
Objectives: Hange-Shashin-To (HST), which is a combination of seven herbs, has previously been used in the treatment of inflammatory or ulcerative gut disease.
Hiroki Matsuoka   +9 more
doaj   +1 more source

Have advances in medical therapy for ulcerative colitis impacted surgical treatment?

open access: yesAnnals of Gastroenterological Surgery, 2023
Aim The purpose of this study was to examine how the clinical characteristics, indications for surgery, and postoperative course of ulcerative colitis (UC) surgical patients changed before and after the introduction of biological agents. Methods Patients
Ryuichi Kuwahara   +5 more
doaj   +1 more source

Pouchitis in inflammatory bowel disease: a review of diagnosis, prognosis, and treatment [PDF]

open access: yesIntestinal Research, 2021
Patients with inflammatory bowel disease (IBD) occasionally need a restorative proctocolectomy with ileal pouch-anal anastomosis (IPAA) because of medically refractory colitis or dysplasia/cancer.
Shintaro Akiyama   +2 more
doaj   +1 more source

Evidence-based clinical practice guidelines for inflammatory bowel disease 2020

open access: yesJournal of gastroenterology, 2021
Inflammatory bowel disease (IBD) is a general term for chronic or remitting/relapsing inflammatory diseases of the intestinal tract and generally refers to ulcerative colitis (UC) and Crohn’s disease (CD).
H. Nakase   +23 more
semanticscholar   +1 more source

GPR65 promotes intestinal mucosal Th1 and Th17 cell differentiation and gut inflammation through downregulating NUAK2

open access: yesClinical and Translational Medicine, 2022
G protein‐coupled receptor 65 (GPR65), a susceptibility gene for inflammatory bowel diseases (IBD), has been identified to promote Th17 cell pathogenicity and induce T cell apoptosis.
Ritian Lin   +9 more
doaj   +1 more source

Gut microbiome structure and metabolic activity in inflammatory bowel disease

open access: yesNature Microbiology, 2018
The inflammatory bowel diseases (IBDs), which include Crohn’s disease (CD) and ulcerative colitis (UC), are multifactorial chronic conditions of the gastrointestinal tract.
E. Franzosa   +26 more
semanticscholar   +1 more source

Cytokines in inflammatory bowel disease [PDF]

open access: yesMediators of Inflammation, 1997
Over the past decade, much has been learned regarding the role of various cytokines in the pathogenesis of inflammatory bowel disease. Several cytokine ‘knockout’ models in mice have been shown to develop colitis, while alterations in the production of various cytokines has been documented in human Crohn′s disease and ulcerative colitis.
Beck, P. L., Wallace, J. L.
openaire   +5 more sources

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