Results 31 to 40 of about 488,838 (371)

Have advances in medical therapy for ulcerative colitis impacted surgical treatment?

open access: yesAnnals of Gastroenterological Surgery, 2023
Aim The purpose of this study was to examine how the clinical characteristics, indications for surgery, and postoperative course of ulcerative colitis (UC) surgical patients changed before and after the introduction of biological agents. Methods Patients
Ryuichi Kuwahara   +5 more
doaj   +1 more source

Health-Related Quality of Life in Inflammatory Bowel Disease [PDF]

open access: yes, 2012
This book is dedicated to inflammatory bowel disease, and the authors discuss the advances in the pathogenesis of inflammatory bowel disease, as well as several new parameters involved in the etiopathogeny of Crohn's disease and ulcerative colitis, such ...
Ramiro Veríssimo
core   +2 more sources

Faecal calprotectin level for assessing endoscopic activity and predicting future clinical course in patients with moderately active ulcerative colitis undergoing granulomonocytapheresis: a prospective cohort study

open access: yesBMC Gastroenterology, 2018
Background Calprotectin is a stable neutrophil protein, which can be measured in faecal samples. The faecal level of calprotectin increases during disease activity in ulcerative colitis (UC).
Takahiro Shimoyama   +3 more
doaj   +1 more source

Metalloproteinases in Inflammatory Bowel Diseases

open access: yesJournal of Inflammation Research, 2021
Inflammatory bowel diseases (IBD) are chronic inflammatory diseases of the gastrointestinal tract, encompassing two main disorders: Crohn's disease (CD) and ulcerative colitis (UC). In both these pathologies, excessive and local immune response against luminal antigens promotes a pathological process leading to various degrees of gut damage.
Maronek M.   +5 more
openaire   +7 more sources

Lifestyle factors associated with inflammatory bowel disease: data from the Swiss IBD cohort study [PDF]

open access: yes, 2023
BACKGROUND: Various environmental risk factors have been associated with the pathogenesis of inflammatory bowel disease. In this study we aimed to identify lifestyle factors that affect the onset of Crohn's disease and ulcerative colitis.
Barry, Mamadou Pathé   +6 more
core   +4 more sources

Clinical features of very early-onset inflammatory bowel disease in Japan: a retrospective single-center study [PDF]

open access: yesIntestinal Research, 2022
Background/Aims Very early-onset inflammatory bowel disease (VEO-IBD), defined as IBD diagnosed in patients younger than 6 years, is a challenge for pediatric gastroenterologists.
Masaaki Usami   +8 more
doaj   +1 more source

Smoking in inflammatory bowel diseases: Good, bad or ugly? [PDF]

open access: yes, 2007
Smoking is an important environmental factor in inflammatory bowel disease (IBD), having different effects in ulcerative colitis (UC) and Crohn’s disease (CD).
Lakatos, László   +2 more
core   +1 more source

Role of therapeutic drug monitoring of azathioprine and thiopurine methyltransferase enzyme status in patients with inflammatory bowel disease: Indian scenario [PDF]

open access: yes, 2020
Inflammatory bowel disease is mainly caused by dysragulated immune system. Inflammatory bowel disease incidences are rising in Asian countries with difficulty in their diagnosis and managements. There is rising the incidences and prevalence rate in India.
Gupta, Kanchan   +3 more
core   +2 more sources

Review of the safety with biologics in inflammatory bowel disease

open access: yesJournal of IMIDs, 2022
Biologics have completely changed the treatment (and life) of patients with inflammatory bowel disease (IBD). After the first ones, anti-tumor necrosis factor (TNF) biologics, two new biologics, with other therapeutic targets, are now in routine use in ...
Andrea Pascual   +3 more
doaj   +1 more source

GPR65 promotes intestinal mucosal Th1 and Th17 cell differentiation and gut inflammation through downregulating NUAK2

open access: yesClinical and Translational Medicine, 2022
G protein‐coupled receptor 65 (GPR65), a susceptibility gene for inflammatory bowel diseases (IBD), has been identified to promote Th17 cell pathogenicity and induce T cell apoptosis.
Ritian Lin   +9 more
doaj   +1 more source

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