Results 71 to 80 of about 1,259,702 (421)

History of Inflammatory Bowel Diseases [PDF]

Journal of Clinical Medicine, 2019
Inflammatory bowel diseases (IBD) are characterized by chronic inflammation of the intestinal mucosa and unknown etiology. In this review, we identified three main eras in the IBD history. Between the 19th and the 20th century, the primary task had been the definition of the diagnostic criteria in order to differentiate the new entity from intestinal ...
Giovanni Clemente Actis, Rinaldo Pellicano, Sharmila Fagoonee, Davide Giuseppe Ribaldone   +3 more
openaire   +4 more sources

Whole-Blood Taurine Concentrations in Cats With Intestinal Disease [PDF]

, 2017
BackgroundIncreased delivery of taurine-conjugated bile acids to the distal bowel can lead to dysbiosis resulting in colitis in mouse models of inflammatory bowel disease.
Awwad, Backus, Backus, Devkota, Duboc, Heinze, Hickman, Hickman, Huxtable, Jacobs, Jergens, Kim, Laflamme, NRC, Rau, Schuller-Levis, Schuller-Levis, Stratton-Phelps, Sugano, Testa, Theisen, Vrieze, Zhang   +22 more
core   +3 more sources

Unraveling the Link between Periodontitis and Inflammatory Bowel Disease: Challenges and Outlook [PDF]

arXiv, 2023
Periodontitis and Inflammatory Bowel Disease (IBD) are chronic inflammatory conditions, characterized by microbial dysbiosis and hyper-immunoinflammatory responses. Growing evidence suggest an interconnection between periodontitis and IBD, implying a shift from the traditional concept of independent diseases to a complex, reciprocal cycle.
arxiv  

Management of Anal Fistula with Crohn's Disease

Journal of the Anus, Rectum and Colon
Crohn's disease (CD) causes gastrointestinal symptoms (i.e., diarrhea and abdominal pain), systemic symptoms (i.e., fatigue, anemia, weight loss, and fever), and perianal fistulas that produce anal pain. Because of the frequent occurrence of diarrhea and
Shota Takano, Yasushi Nakamura, Kohei Tamaoka, Takafumi Yoshimoto, Yasue Irei, Yoriyuki Tsuji   +5 more
doaj   +1 more source

Rectal carcinoma with dual differentiation toward enteroblastic and neuroendocrine features arising in a patient with ulcerative colitis: a case report

World Journal of Surgical Oncology, 2022
Background Colorectal carcinoma with enteroblastic differentiation is a rare subtype of colorectal carcinomas expressing at least one characteristic immunohistochemical marker among α-fetoprotein, glypican-3, and spalt-like transcription factor 4. On the
Takako Kihara, Ryuichi Kuwahara, Kurando Kusunoki, Tomohiro Minagawa, Yuki Horio, Motoi Uchino, Hiroki Ikeuchi, Seiichi Hirota   +7 more
doaj   +1 more source

Network analysis of a complex disease: the gut microbiota in the inflammatory bowel disease case [PDF]

arXiv, 2022
Inflammatory bowel diseases (IBD) are complex diseases in which the gut microbiota is attacked by the immune system of genetically predisposed subjects when they are exposed to yet unclear environmental factors. The complexity of this class of diseases makes them suitable to be represented and studied with network science.
arxiv  

Interpretable histopathology-based prediction of disease relevant features in Inflammatory Bowel Disease biopsies using weakly-supervised deep learning [PDF]

arXiv, 2023
Crohn's Disease (CD) and Ulcerative Colitis (UC) are the two main Inflammatory Bowel Disease (IBD) types. We developed deep learning models to identify histological disease features for both CD and UC using only endoscopic labels. We explored fine-tuning and end-to-end training of two state-of-the-art self-supervised models for predicting three ...
arxiv  

Leveraging current insights on IL‐10‐producing dendritic cells for developing effective immunotherapeutic approaches

FEBS Letters, EarlyView.
In vivo IL‐10 produced by tissue‐resident tolDC is involved in maintaining/inducing tolerance. Depending on the agent used for ex vivo tolDC generation, cells acquire common features but prime T cells towards anergy, FOXP3+ Tregs, or Tr1 cells according to the levels of IL‐10 produced. Ex vivo‐induced tolDC were administered to patients to re‐establish/
Konstantina Morali, Gloria Giacomello, Michela Vuono, Silvia Gregori   +3 more
wiley   +1 more source

Cutaneous Manifestations in Inflammatory Bowel Diseases [PDF]

, 2015
Inflammatory bowel diseases have a high frequency in Europe. They are chronic disorders that evolve with relapses and remissions. Clinical features include the signs of underlying inflammatory bowel disease and also signs of extraintestinal ...
Benea, Vasile, Costescu, Monica, Georgescu, Simona Roxana, Mitran, Cristina Iulia, Mitran, Madalina Irina, Sarbu, Maria Isabela, Tampa, Mircea   +6 more
core   +2 more sources

Mechanisms of Intestinal Epithelial Barrier Dysfunction by Adherent-Invasive Escherichia coli. [PDF]

, 2016
Pathobiont expansion, such as that of adherent-invasive Escherichia coli (AIEC), is an emerging factor associated with inflammatory bowel disease. The intestinal epithelial barrier is the first line of defense against these pathogens.
McCole, Declan F, Shawki, Ali
core   +1 more source