Results 101 to 110 of about 3,411,578 (286)

Re‐Purposing Sapropterin (Kuvan) for ACTA2‐Related Multisystemic Smooth Muscle Dysfunction Syndrome: A Translational Mechanistic and First‐In‐Human Therapeutic Report

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Multisystemic smooth muscle dysfunction syndrome (MSMDS) is an ultra‐rare, ACTA2‐related disorder characterized by severe cerebrovascular disease, aortic aneurysms, and smooth muscle dysfunction. Using molecular dynamics simulations and in silico drug screening, we identified that sapropterin dihydrochloride (Kuvan) is a candidate capable of ...
Moran Hausman‐Kedem   +9 more
wiley   +1 more source

Evaluation Of Glp-2 Levels In Crohn's Disease

open access: yes, 2017
221S58S58Advances-in-Inflammatory-Bowel-Diseases-Crohn's-and-Colitis Foundation's National Clinical and Research ConferenceDEC 10-12, 2015Orlando ...
Antonio; Vasques   +8 more
core  

Adalimumab Biosimilar in Pediatric Inflammatory Bowel Disease: A Retrospective Study from the Sicilian Network for Inflammatory Bowel Disease (SN-IBD) [PDF]

open access: yes
Background: The utilization of anti-tumor necrosis factor-alpha (anti-TNF-alpha) biosimilars in inflammatory bowel disease (IBD) is constantly increasing. However, pediatric data are limited.
Francesco Graziano   +21 more
core   +1 more source

Glucagon‐Like Peptide‐1 Receptor Agonists in Multiple Sclerosis: A Topical Narrative Review

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT The glucagon‐like peptide‐1 (GLP‐1) receptor agonists (RAs) are a relatively new class of drugs that were initially approved by the US Food and Drug Administration to improve glycemic control in patients with type 2 diabetes mellitus and, subsequently, weight reduction in patients with obesity.
Audrey Y. Chang, Farrah J. Mateen
wiley   +1 more source

Factors Associated With Decreased Bone Mineral Density In Patients With Crohn's Disease

open access: yes, 2017
231S11S12Advances-in-Inflammatory-Bowel-Diseases-Crohn's-and-Colitis Foundation's National Clinical and Research ConferenceDEC 08-10, 2016Orlando ...
Rita   +9 more
core  

Respiratory system involvement in inflammatory bowel diseases [PDF]

open access: yes, 2017
  Inflammatory bowel diseases are systemic disorders that can manifest in any location. The problem of respiratory system involvement is very important form clinical point of view. In the article we try to systematize the current knowledge on this topic.
Kus, Jan; 1st Department of Lung Diseases, National Tuberculosis and Lung Diseases Research Institute, Warsaw, Poland   +5 more
core   +1 more source

Discordance Between Patient and Physician Global Assessments in Early Systemic Sclerosis

open access: yesArthritis Care &Research, EarlyView.
Objective This study aims to identify factors associated with patient global assessment (PtGA) and physician global assessment (PhGA) and discordance between them in systemic sclerosis (SSc). Methods Data from adults with early SSc (<5 years) from the Collaborative National Quality and Efficacy Registry were included.
Ellen Romich   +35 more
wiley   +1 more source

Therapy With Lupeol, A Natural Pentacyclic Triterpenoid, Attenuates Intestinal Inflammation In Rat

open access: yes, 2017
231S83S84Advances-in-Inflammatory-Bowel-Diseases-Crohn's-and-Colitis Foundation's National Clinical and Research ConferenceDEC 08-10, 2016Orlando ...
Socca   +9 more
core  

Evaluation of the serum levels of the incretins (glp-1 and Gip) and Dpp-iv in Crohn's disease

open access: yes, 2017
FAPESP - FUNDAÇÃO DE AMPARO À PESQUISA DO ESTADO DE SÃO PAULO221S58S58FAPESP - FUNDAÇÃO DE AMPARO À PESQUISA DO ESTADO DE SÃO PAULOFAPESP - FUNDAÇÃO DE AMPARO À PESQUISA DO ESTADO DE SÃO PAULO2014/06164-8Advances-in-Inflammatory-Bowel-Diseases-Crohn's ...
Geloneze, Bruno   +7 more
core   +1 more source

Unreliable information and fear: Barriers to vaccination among IBD patients in China

open access: yesHuman Vaccines & Immunotherapeutics
Vaccination plays a crucial role in safeguarding individuals with inflammatory bowel disease (IBD) from potential epidemics. In light of the resurgence of COVID-19 in China, unvaccinated IBD patients are vulnerable to infection and potentially serious ...
Jingwen Liu   +4 more
doaj   +1 more source

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