Results 111 to 120 of about 380,200 (294)

The Full Picture of Ulcerative Colitis: The Burden, the Patient, the Treatment [PDF]

European Medical Journal Gastroenterology, 2015
Ulcerative colitis (UC) carries a significant, progressive disease burden that is often underestimated or misinterpreted by healthcare providers. Adverse outcomes have a major impact on patient quality of life, with a significant burden of symptoms both ...
Julián Panés, Edouard Louis, Paul Rutgeerts   +2 more
doaj  

Smart, Bio‐Inspired Polymers and Bio‐Based Molecules Modified by Zwitterionic Motifs to Design Next‐Generation Materials for Medical Applications

Advanced Functional Materials, EarlyView.
Bio‐based and (semi‐)synthetic zwitterion‐modified novel materials and fully synthetic next‐generation alternatives show the importance of material design for different biomedical applications. The zwitterionic character affects the physiochemical behavior of the material and deepens the understanding of chemical interaction mechanisms within the ...
Theresa M. Lutz, Jonas De Breuck, Sahar Salehi, Meike N. Leiske   +3 more
wiley   +1 more source

3D‐Printed Porous Hydroxyapatite Formed via Enzymatic Mineralization

Advanced Functional Materials, EarlyView.
Bone combines lightness, strength, and the ability to heal, inspiring new materials design. This work introduces a room‐temperature, enzyme‐mediated 3D printing method to create porous hydroxyapatite scaffolds. The process avoids energy‐intensive sintering, preserves bioactivity, and allows control over porosity and mineralization.
Francesca Bono, Anna Puiggalí‐Jou, Greta Cocchi, Mariangela Miccoli, Katharina Maniura‐Weber, Marcy Zenobi‐Wong, Esther Amstad   +6 more
wiley   +1 more source

The Bowel Microbiota and Inflammatory Bowel Diseases

International Journal of Inflammation, 2010
The human bowel contains a large and biodiverse bacterial community known as the microbiota or microbiome. It seems likely that the microbiota, fractions of the microbiota, or specific species comprising the microbiota provide the antigenic fuel that ...
Gerald W. Tannock
doaj   +1 more source

Consumed by Abdominal Distention

Arthritis Care &Research, EarlyView.
Abimbola Fadairo‐Azinge, James Grenert, Brian Haas, Mary Margaretten   +3 more
wiley   +1 more source

In Situ 3D Bioprinting: Impact of Cross‐Linking on the Adhesive Properties of Hydrogels

Advanced Functional Materials, EarlyView.
In situ 3D bioprinting enables the direct deposition of cell‐laden, adhesive biomaterials for on‐site tissue regeneration. This review provides a comprehensive overview of how cross‐linking influences the bioadhesive properties of hydrogels used in 3D bioprinting, highlighting cross‐linking triggers, bioadhesion mechanisms, polymer interpenetration ...
Odile Romero Fernandez, Mulazim Hussain Asim, Shumaila Arshad, Gergely Kali, Andreas Bernkop‐Schnürch   +4 more
wiley   +1 more source

The mesenteric adipokine SFRP5 alleviated intestinal epithelial apoptosis improving barrier dysfunction in Crohn's disease

iScience
Summary: The hypertrophic mesenteric adipose tissue (htMAT) of Crohn disease (CD) participates in inflammation through the expression of adipokines, but the exact mechanism of this action in the intestine is unknown.
Xiaofeng Zhang, Lugen Zuo, Xue Song, Wenjing Zhang, Zi Yang, Zhiyuan Wang, Yibing Guo, Sitang Ge, Lian Wang, Yueyue Wang, Zhijun Geng, Jing Li, Jianguo Hu   +12 more
doaj   +1 more source

Strategies for Loading and Releasing Peptide Therapeutics in Biodegradable Carriers

Advanced Functional Materials, EarlyView.
A biodegradable carrier‐based peptide delivery system is a powerful treatment platform for diverse diseases, owing to its superior therapeutic efficacy and low toxicity. This review examines the conventional peptide‐loaded carrier fabrication process and its current limitations.
Wookyoung Jang, Ki Wan Bong
wiley   +1 more source

Ulcerative colitis-risk loci on chromosomes 1p36 and 12q15 found by genome-wide association study. [PDF]

, 2009
Ulcerative colitis is a chronic inflammatory disease of the colon that presents as diarrhea and gastrointestinal bleeding. We performed a genome-wide association study using DNA samples from 1,052 individuals with ulcerative colitis and preexisting data ...
Abraham, Clara, Achkar, Jean-Paul, Annese, Vito, Barmada, M Michael, Bayless, Theodore M, Bossa, Fabrizio, Brant, Steven R, Cho, Judy H, Daly, Mark J, Duerr, Richard H, Goyette, Philippe, Gregersen, Peter K, Griffiths, Anne M, Ippoliti, Andrew F, Kistner, Emily O, Klei, Lambertus, Lahaie, Raymond G, Latiano, Anna, Lee, Annette T, McGovern, Dermot PB, Paré, Pierre, Proctor, Deborah D, Regueiro, Miguel D, Rioux, John D, Roeder, Kathryn, Rotter, Jerome I, Schumm, L Philip, Scott, Regan, Silverberg, Mark S, Steinhart, A Hillary, Targan, Stephan R, Taylor, Kent D, Wu, Jing, Xu, Wei   +33 more
core  

An Edible H2O2 Biosensor for Gastrointestinal Metabolites and Peroxidase Enzyme Quantification

Advanced Healthcare Materials, EarlyView.
We present an edible biosensor for gastric fluid analysis that integrates a caffeic acid–horseradish peroxidase redox system into an edible electrolyte‐gated transistor. The device enables rapid, low‐volume detection of H2O2 and, with minimal modification, metabolites and enzyme activity in simulated gastrointestinal conditions.
Valerio Francesco Annese, Elena Feltri, Pietro Rossi, Valerio Galli, Cristiano Bortolotti, João Paulo Vita Damasceno, Ivan K. Ilic, Dario Natali, Alessandro Luzio, Adrica Kyndiah, Mario Caironi   +10 more
wiley   +1 more source