Results 111 to 120 of about 387,427 (329)

Chronic Stress, Inflammation, and Colon Cancer: A CRH System-Driven Molecular Crosstalk. [PDF]

, 2019
Chronic stress is thought to be involved in the occurrence and progression of multiple diseases, via mechanisms that still remain largely unknown. Interestingly, key regulators of the stress response, such as members of the corticotropin-releasing ...
Baritaki, Stavroula, Chatzaki, Ekaterini, de Bree, Eelco, Pothoulakis, Charalabos   +3 more
core   +1 more source

Time‐Controlled Dual Targeting to Program Systemic and Intercellular Transfer of Therapeutic Effects

Advanced Functional Materials, EarlyView.
Aspirin‐liposomes loaded onto monocytes enable inflammation‐triggered targeting and efficient hand‐over of aspirin to inflamed cells. Monocytes uptake a significant portion of aspirin‐liposomes, prolonging therapeutic action. This approach enhances anti‐inflammatory effects through intercellular transfer, demonstrating a translational strategy for ...
Seung Eun Yu, Jueun Kim, Dae‐Hyun Kim, Sewoom Baek, Suji Park, Seyong Chung, Hak‐Joon Sung   +6 more
wiley   +1 more source

Inflammatory bowel disease [PDF]

Alimentary Pharmacology & Therapeutics, 2003
R. W. Stockbrugger, M. R. B. Keighley
openaire   +4 more sources

A prospective evaluation of the predictive value of faecal calprotectin in quiescent Crohn’s disease [PDF]

, 2014
Background: The faecal calprotectin (FC) test is a non-invasive marker for gastrointestinal inflammation. Aim: To determine whether higher FC levels in individuals with quiescent Crohn’s disease are associated with clinical relapse over the ensuing 12 ...
Allan J. Morris, Beltrán, Best, Boschetti, Centre for Evidence-based purchasing, Cosnes, Costa, D'Haens, D'Incà, Daniel R. Gaya, De Suray, Ferreiro, García-Sánchez, Gisbert, Gisbert, Graham D. Naismith, Guidi, Hanaway, Jack W. Winter, Joanna I. Munro, Jones, Kallel, Karen Rankin, Kennedy, Laharie, Lamb, Langhorst, Lemann, Louis, Lyn A. Smith, Manz, Mao, Molander, Naismith, Pardi, Primas, Roseth, Roseth, Roseth, Sarah J.E. Barry, Saverymuttu, Schoepfer, Schoepfer, Sipponen, Sipponen, Susan Laird, Sutherland, Tibble, Tibble, Van Rheenen, Wagner   +50 more
core   +1 more source

Photothermal Hydrogel with Mn3O4 Nanoparticles Alleviates Intervertebral Disc Degeneration by Scavenging ROS and Regulating Extracellular Matrix Metabolism

Advanced Functional Materials, EarlyView.
The MPTT‐nanozyme‐hydrogel system (Mn3O4@ChS‐HA) provides a multifunctional therapeutic strategy for intervertebral disc degeneration (IVDD), effectively targeting oxidative stress and enhancing AF repair by restoring extracellular matrix (ECM) and redox homeostasis.
Yangyang Chen, Chan Xue, Feifei Ni, Binwu Hu, Miaoheng Yan, He Zhang, Yuxiang Hu, Xiaoyao Peng, Guangfang Li, Yu Han, Hongjian Liu, Zengwu Shao, Qin Wang, Yulong Wei   +13 more
wiley   +1 more source

Intraoral Drug Delivery: Bridging the Gap Between Academic Research and Industrial Innovations

Advanced Functional Materials, EarlyView.
Intraoral drug delivery offers a promising route for systemic and localized therapies, yet challenges such as enzymatic degradation, limited permeability, and microbial interactions hinder efficacy. This figure highlights innovative strategies—mucoadhesive materials, enzyme inhibitors, and permeation enhancers—to overcome these barriers.
Soheil Haddadzadegan, Simona Summonte, Fabrizio Ricci, Matthias Sandmeier, Andreas Bernkop‐Schnürch   +4 more
wiley   +1 more source

Unreliable information and fear: Barriers to vaccination among IBD patients in China

Human Vaccines & Immunotherapeutics
Vaccination plays a crucial role in safeguarding individuals with inflammatory bowel disease (IBD) from potential epidemics. In light of the resurgence of COVID-19 in China, unvaccinated IBD patients are vulnerable to infection and potentially serious ...
Jingwen Liu, Zelin Yan, Wen Hu, Shuyan Li, Yan Chen   +4 more
doaj   +1 more source

The Full Picture of Ulcerative Colitis: The Burden, the Patient, the Treatment [PDF]

European Medical Journal Gastroenterology, 2015
Ulcerative colitis (UC) carries a significant, progressive disease burden that is often underestimated or misinterpreted by healthcare providers. Adverse outcomes have a major impact on patient quality of life, with a significant burden of symptoms both ...
Julián Panés, Edouard Louis, Paul Rutgeerts   +2 more
doaj  

The immune competence of patients with inflammatory bowel disease [PDF]

, 1974
P.M. Bolton, Susan James, Robert G. Newcombe, R Whitehead, L E Hughes   +4 more
openalex   +1 more source

Biomaterial Strategies for Targeted Intracellular Delivery to Phagocytes

Advanced Functional Materials, EarlyView.
Phagocytes are essential to a functional immune system, and their behavior defines disease outcomes. Engineered particles offer a strategic opportunity to target phagocytes, harnessing inflammatory modulation in disease. By tuning features like size, shape, and surface, these systems can modulate immune responses and improve targeted treatment for a ...
Kaitlyn E. Woodworth, Neal I. Callaghan, Locke Davenport Huyer   +2 more
wiley   +1 more source