Results 71 to 80 of about 3,411,578 (286)

Inflammatory bowel disease-specific autoantibodies in HLA-B27-associated spondyloarthropathies: Increased prevalence of ASCA and pANCA [PDF]

, 2004
Aims: An association between inflammatory bowel disease (IBD) and spondyloarthropathies (SpA) has repeatedly been reported. The aim of the present study was to investigate whether serologic markers of IBD, e. g.
Folwaczny, Christian, Kellner, H., J. Glas, Marker-Hermann, E., R. Gruber, Brumberger, V., V. Brumberger, Glas, J., Gruber, R., H. Kellner, C. Folwaczny, Török, H.-P., E. Märker-Hermann, C. Strasser, Strasser, C., H.-P. Török   +15 more
core   +1 more source

Metastatic niche shaped by host factors influences disseminated cancer cell fate

FEBS Letters, EarlyView.
Metastasis is shaped not only by cancer cells but also by the environments they encounter. This review explores how factors such as aging, diet, the microbiome, lifestyle, and environmental exposures remodel organ‐specific niches in the lung, liver, bone, and brain, influencing where metastatic cells survive, remain dormant, or grow, and ultimately ...
Gwennan Delyth Ward, Álvaro Ruiz‐Tabas, Patricia Altea‐Manzano   +2 more
wiley   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

Molecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Prevalence of Anemia in Inflammatory Bowel Diseases in European Countries: A Systematic Review and Individual Patient Data Meta-analysis.

, 2014
The main objective is to determine the overall prevalence of anemia in inflammatory bowel diseases (IBD) in ...
Bager, Palle, Lindgren, Stefan, Lindgren, Stefan,, S. R. Vavricka, Koutroubakis, Ioannis, Blumenstein, Irina, B. Moum, I. Blumenstein, Rey, Julia, J. Rey, Bergamaschi, Gaetano, Morena, Felipe de la, Ardizzone, Sandro, G. Bergamaschi, I. Koutroubakis, Schröder, Oliver, Schneeweiss, Sven, Herrmann, Eva, N. Filmann, S. Schneeweiss, Filmann, Natalie, P. Bager, Moum, Bjørn, O. Schröder, S. Lindgren, E. Herrmann, S. Ardizzone, Vavricka, Stephan R, Lund University., F. De La Morena   +29 more
core   +1 more source

IgG-seq identifies immune-reactive enteric bacteria in Crohn’s disease with spondyloarthritis

Gut Microbes
Joint inflammation is the most common extraintestinal manifestation of Crohn’s disease (CD). Although alterations in the enteric microbiota are described in CD with spondyloarthritis (CD-SpA), it is not known whether distinct taxa serve as markers for ...
Grace A. Maldarelli, Maeva Metz, Seun Oguntunmibi, Nancy Tran, Grace Xiang, Dana Lukin, Ellen J. Scherl, Randy S. Longman   +7 more
doaj   +1 more source

Loss of proton‐sensing TDAG8 increases tumor progression in mouse models of colon cancer

Molecular Oncology, EarlyView.
Loss of the pH‐sensing receptor TDAG8 accelerates colorectal cancer progression in mice. Animals lacking TDAG8 expression had increased tumor growth, DNA damage, and recruitment of tumor‐associated immune cells, including macrophages, neutrophils, and monocytes.
Ermanno Malagola, Yasmine Illi, Anna Bircher, Marijn Wilmink, Rachele F. Malagutti, Solenn Ottié, Cordelia Schuler, Pedro A. Ruiz, Cheryl de Vallière, Klaus Seuwen, Gerhard Rogler, Martin Hausmann   +11 more
wiley   +1 more source

PANoptosis in the pathogenesis of myelodysplastic syndromes

Molecular Oncology, EarlyView.
PANoptosis, a combination of three types of programmed cell death, is mediated by a large protein complex called a PANoptosome. In healthy bone marrow hematopoietic cells, PANoptosis is restricted by inhibitory signaling. In MDS, bone marrow cells become sensitive to the PANoptotic stimuli due to the aberrant inactivation of inhibitory signaling or ...
Rohit Thalla, Jyoti Lamichhane, Cameron Lewis, Peter Breslin, Jiwang Zhang   +4 more
wiley   +1 more source

Gut microbiota alterations in patients with non‐small‐cell lung cancer undergoing chemoradiotherapy

Molecular Oncology, EarlyView.
We investigated the impact of concurrent chemoradiotherapy (CRT) on the gut microbiota in patients with locally advanced non‐small‐cell lung cancer. Overall gut microbiota composition remained largely stable throughout CRT while antibiotic exposure may influence microbial diversity.
Hanne Marte Nymoen, Zhi Zhao, Henrik Horndalsveen, Maria Moksnes Bjaanæs, Bjørn Henning Grønberg, Tarje Halvorsen, Tesfaye Madebo, Marianne Aanerud, Jussi Koivunen, Kersti Oselin, Saulius Cicenas, Nina Helbekkmo, Jarkko Ahvonen, Maria Silvoniemi, Tine Norman Alver, Tonje Dalen, Åsa Kristina Öjlert, Saima Jamil Farooqi, Åslaug Helland, Vilde Drageset Haakensen   +19 more
wiley   +1 more source

CEACAM6 gene variants in inflammatory bowel disease. [PDF]

, 2011
The carcinoembryonic antigen-related cell adhesion molecule 6 (CEACAM6) acts as a receptor for adherent-invasive E. coli (AIEC) and its ileal expression is increased in patients with Crohn's disease (CD). Given its contribution to the pathogenesis of CD,
Seiderer, J., Darina Czamara, Seiderer Julia, Ochsenkühn, Thomas, Ulrich Lass, Fries, C., Beigel, F., Glas, J., Müller-Myhsok, B., Czamara, D., Bertram Müller-Myhsok, Diegelmann Julia, Fries Christoph, Tillack, Cornelia, Lass, U., Pfennig Simone, Brand, Stephan, Göke, B., Brand Stephan, Thomas Ochsenkühn, Weidinger Maria, Olszak Torsten, Beigel, Florian, Weidinger, Maria, Ochsenkühn, T., Christiane Wolf, Wolf, Christiane, Cornelia Tillack, Julia Diegelmann, Beigel Florian, Müller-Myhsok Bertram, Göke, Burkhard, Lass Ulrich, Fries, Christoph, Pfennig, S., Pfennig, Simone, Peter Lohse, Seiderer, Julia, Glas, Jürgen, Diegelmann, J., Lohse, P., Christoph Fries, Ochsenkühn Thomas, Müller-Myhsok, Bertram, Weidinger, M., Burkhard Göke, Göke Burkhard, Stephan Brand, Wolf, C., Maria Weidinger, Brand, S., Czamara, Darina, Jürgen Glas, Tillack Cornelia, Wolf Christiane, Lass, Ulrich, Czamara Darina, Lohse, Peter, Diegelmann, Julia, Simone Pfennig, Glas Jürgen, Torsten Olszak, Olszak, T., Florian Beigel, Lohse Peter, Julia Seiderer, Olszak, Torsten, Tillack, C.   +67 more
core   +2 more sources

Prevalence of Joint Hypermobility and Patterns of Articular Manifestations in Patients with Inflammatory Bowel Disease

Gastroenterology Research and Practice, 2009
Objective. The objective is the investigation of Joint Hypermobility (JH) and the Hypermobility Syndrome (HMS) in patients with inflammatory bowel disease (IBD). Methods. We examined 83 patients with IBD and 67 healthy individuals for the presence of JH.
P. Vounotrypidis, E. Efremidou, P. Zezos, M. Pitiakoudis, E. Maltezos, N. Lyratzopoulos, G. Kouklakis   +6 more
doaj   +1 more source