Results 51 to 60 of about 4,711,883 (288)
How structural disorder and polyelectrolyte properties of prothymosin α enable its large interactome
FEBS Letters, EarlyView.In this review, complexes of the fully disordered and highly negatively charged prothymosin α are collected, described, and discussed. Linked to its poly‐electrostatic character, prothymosin α engages a large interactome through multiple different binding modes ranging from fully disordered complexes to short linear motif (SLiM)‐driven interactions ...
Ketty C. Tamburrini +3 more
wiley +1 more source
npj Precision OncologyTriple-negative inflammatory breast cancer (TN-IBC) is the most aggressive type of breast cancer, yet its defining genomic, molecular, and immunological features remain largely unknown.
Xiaoping Wang +23 more
doaj +1 more source
Association between local inflammation and breast tissue age-related lobular involution among premenopausal and postmenopausal breast cancer patients. [PDF]
PLoS ONE, 2017 Increased levels of pro-inflammatory markers and decreased levels of anti-inflammatory markers in the breast tissue can result in local inflammation. We aimed to investigate whether local inflammation in the breast tissue is associated with age-related ...
Mirette Hanna +8 more
doaj +1 more source
A New N-staging System for Predicting Postoperative Survival of M0 Stage Inflammatory Breast Cancer
Zhongliu Fangzhi Yanjiu, 2022 Objective To establish a new N-stage system combining the number of metastatic lymph nodes and the ratio of metastatic lymph nodes for postoperative M0 stage inflammatory breast cancer patients.
SUI Daxing, WANG Xueying, ZHANG Jiaxin
doaj +1 more source
Inflammatory breast cancer-importance of breast imaging
European Journal of Surgical Oncology, 2018 Inflammatory breast cancer (IBC) is a rare form of primary cancer and accounts for only 1-5 % of all breast cancer types.[1–3] It is classified as T4d stage by TNM classification,[4] the most aggressive form of breast cancer with a 20%–30% incidence of distant metastasis at the time of diagnosis[5] and poorer prognosis than the non-IBC locally advanced
Papalouka, Vasiliki, Gilbert, Fiona J
openaire +3 more sources
Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer
Molecular Oncology, EarlyView.Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
wiley +1 more source
Saudi Pharmaceutical Journal, 2023 Store-operated calcium entry (SOCE) is an important pathway for calcium signaling that regulates calcium influx across the plasma membrane upon the depletion of calcium stores in the endoplasmic reticulum.
Abdullah S. Alhamed +11 more
doaj +1 more source
Molecular Oncology, EarlyView.This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska +13 more
wiley +1 more source
Challenging a Misnomer? The Role of Inflammatory Pathways in Inflammatory Breast Cancer
Mediators of Inflammation, 2017 Inflammatory breast cancer is a rare, yet highly aggressive form of breast cancer, which accounts for less than 5% of all locally advanced presentations.
Riley J. Morrow +3 more
doaj +1 more source
An update on inflammatory breast cancer
Oncology Reviews, 2011 Inflammatory breast cancer is one of the most aggressive forms of breast cancer. Once considered to be a uniformly fatal disease, treatment of this entity has evolved significantly over the last two decades.
P. Thapaliya, N. J. Karlin
doaj +1 more source