Results 51 to 60 of about 301,386 (199)

Inflammatory breast cancer-importance of breast imaging

European Journal of Surgical Oncology, 2018
Inflammatory breast cancer (IBC) is a rare form of primary cancer and accounts for only 1-5 % of all breast cancer types.[1–3] It is classified as T4d stage by TNM classification,[4] the most aggressive form of breast cancer with a 20%–30% incidence of distant metastasis at the time of diagnosis[5] and poorer prognosis than the non-IBC locally advanced
Papalouka, Vasiliki, Gilbert, Fiona J
openaire   +3 more sources

The chemopreventive polyphenol Curcumin prevents hematogenous breast cancer metastases in immunodeficient mice [PDF]

, 2007
Dissemination of metastatic cells probably occurs long before diagnosis of the primary tumor. Metastasis during early phases of carcinogenesis in high risk patients is therefore a potential prevention target.
Iancu, Cristina M., Albini, Adriana, Bachmeier, Beatrice E., Dell'Eva, Raffaella, Cilli, Michele, Vene, Roberta, Jochum, Marianne, Pfeffer, Ulrich, Schleicher, Erwin, Nerlich, Andreas G.   +9 more
core   +1 more source

Genomic and transcriptomic analyses identify distinctive features of triple-negative inflammatory breast cancer

npj Precision Oncology
Triple-negative inflammatory breast cancer (TN-IBC) is the most aggressive type of breast cancer, yet its defining genomic, molecular, and immunological features remain largely unknown.
Xiaoping Wang, Li Zhao, Xingzhi Song, Xiaogang Wu, Savitri Krishnamurthy, Takashi Semba, Shan Shao, Mark Knafl, Larry W. Coffer, Angela Alexander, Anita Vines, Swetha Bopparaju, Wendy A. Woodward, Randy Chu, Jianhua Zhang, Clinton Yam, Lenora W. M. Loo, Azadeh Nasrazadani, Le-Petross Huong, Scott E. Woodman, Andrew Futreal, Rare Tumor Initiative Team, Debu Tripathy, Naoto T. Ueno   +23 more
doaj   +1 more source

Association between local inflammation and breast tissue age-related lobular involution among premenopausal and postmenopausal breast cancer patients. [PDF]

PLoS ONE, 2017
Increased levels of pro-inflammatory markers and decreased levels of anti-inflammatory markers in the breast tissue can result in local inflammation. We aimed to investigate whether local inflammation in the breast tissue is associated with age-related ...
Mirette Hanna, Isabelle Dumas, Michèle Orain, Simon Jacob, Bernard Têtu, François Sanschagrin, Alexandre Bureau, Brigitte Poirier, Caroline Diorio   +8 more
doaj   +1 more source

Challenging a Misnomer? The Role of Inflammatory Pathways in Inflammatory Breast Cancer

Mediators of Inflammation, 2017
Inflammatory breast cancer is a rare, yet highly aggressive form of breast cancer, which accounts for less than 5% of all locally advanced presentations.
Riley J. Morrow, Nima Etemadi, Belinda Yeo, Matthias Ernst   +3 more
doaj   +1 more source

The role of Th-17 cells and IL-17 in the metastatic spread of breast cancer: As a means of prognosis and therapeutic target

Frontiers in Immunology, 2023
Metastatic breast cancer is one of the most common and well-known causes of death for women worldwide. The inflammatory tumor cell and other cancer hallmarks dictate the metastatic form and dissemination of breast cancer.
Tewodros Shibabaw, Banchamlak Teferi, Birhanu Ayelign, Birhanu Ayelign   +3 more
doaj   +1 more source

Inflammatory breast cancer: High incidence of GCC haplotypes (−1082A/G, −819T/C, and −592A/C) in the interleukin-10 gene promoter correlates with over-expression of interleukin-10 in patients’ carcinoma tissues

Tumor Biology, 2017
Interleukin-10 is involved in carcinogenesis by supporting tumor escape from the immune response. The aim of this study was to assess the single nucleotide polymorphisms, −1082A/G, −819T/C and −592A/C, in interleukin-10 gene promoter in inflammatory ...
Salwa Sabet, Shrouk Khalaf El-Sayed, Hossam Taha Mohamed, Mohamed El-Shinawi, Mona M Mohamed   +4 more
doaj   +1 more source

Diversity and heterogeneity in human breast cancer adipose tissue revealed at single-nucleus resolution

Frontiers in Immunology, 2023
IntroductionThere is increasing awareness of the role of adipose tissue in breast cancer occurrence and development, but no comparison of adipose adjacent to breast cancer tissues and adipose adjacent to normal breast tissues has been reported ...
Lina Tang, Tingting Li, Jing Xie, Yanping Huo, Jianping Ye, Jianping Ye, Jianping Ye   +6 more
doaj   +1 more source

Gene expression analysis in human breast cancer associated blood vessels

, 2012
Angiogenesis is essential for solid tumour growth, whilst the molecular profiles of tumour blood vessels have been reported to be different between cancer types.
John M J Herbert, Jones, DT, Richard Mitter, John M. J. Herbert (132335), Jones D. T., Bicknell, R, Francesca Buffa, Adrian L. Harris (132344), Li Ji-Liang, Li, J-L, Herbert, JMJ, Mitter Richard, Roy Bicknell (54952), Harris A. L., Buffa F., Buffa, Francesca, Mitter, R, Adrian L Harris, Kairbaan Hodivala-Dilke, J Louise Jones, Tanguy Lechertier, Lechertier Tanguy, Tanguy Lechertier (132331), Herbert, JM, Roy Bicknell, Kairbaan Hodivala-Dilke (132348), Herbert John M. J., Lechertier, T, Harris Adrian L., Lechertier T., Francesca Buffa (132341), Hodivala-Dilke Kairbaan, Mitter R., Hodivala-Dilke, K, Jones J. Louise, Ji-Liang Li (132339), Jones, JL, Harris, AL, Buffa, F, Richard Mitter (132333), Bicknell Roy, Li, JL, Dylan T. Jones (132329), Dylan T Jones, Jones Dylan T., Bicknell R., Ji-Liang Li, Herbert J. M. J., Li J. -L., J. Louise Jones (132337), Buffa Francesca, Jones J. L., Hodivala-Dilke K.   +52 more
core   +1 more source

13R,20-Dihydroxydocosahexaenoic Acid, a Novel Dihydroxy- DHA Derivative, Inhibits Breast Cancer Stemness through Regulation of the Stat3/IL-6 Signaling Pathway by Inducing ROS Production

Antioxidants, 2021
Breast cancer is a major health problem worldwide. Cancer stem cells (CSCs) are known to mediate breast cancer metastasis and recurrence and are therefore a promising therapeutic target.
Lifang Wang, Hack Sun Choi, Binna Lee, Jong Hyun Choi, Yong-Suk Jang, Jeong-Woo Seo   +5 more
doaj   +1 more source