Results 61 to 70 of about 301,386 (199)

A positive feedback loop driven by fibronectin and IL-1 beta sustains the inflammatory microenvironment in breast cancer

, 2023
Inflammatory alterations of the extracellular matrix shape the tumor microenvironment and promote all stages of carcinogenesis. This study aims to determine the impact of cellular fibronectin on inflammatory facets of tumor-associated macrophages (TAMs ...
Esendagli, Gunes,, Yilmaz, Kerim Bora,, Georgios Efthymiou, Ellen Van Obberghen-Schilling, Gunes Esendagli, Demirkol-Canli, Secil,, Efthymiou, Georgios, Tunali, Gürcan, Yanik, Hamdullah, Suleyman Can Ozturk, Kerim Bora Yilmaz, Demirkol-Canli, Secil, Hamdullah Yanik, Esendagli, Gunes, Tunali, Gürcan,, Ozturk, Suleyman Can,, Van Obberghen-Schilling, Ellen,, Van Obberghen-Schilling, Ellen, Efthymiou, Georgios,, DEMİRKOL CANLI, SEÇİL, Gurcan Tunali, Yilmaz, Kerim Bora, Ozturk, Suleyman Can, Yanik, Hamdullah,, Secil Demirkol-Canli   +24 more
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Altered ribosomal profile in acquired resistance and reversal associates with pathological response to chemotherapy in inflammatory breast cancer

npj Breast Cancer
Therapeutic resistance presents a significant hurdle in combating inflammatory breast cancer (IBC), adding to the complexity of its management. To investigate these mechanisms, we conducted a comprehensive analysis using transcriptomic and proteomic ...
Gayathri R. Devi, Pritha Pai, Seayoung Lee, Matthew W. Foster, Dorababu S. Sannareddy, Francois Bertucci, Naoto Ueno, Steven Van Laere   +7 more
doaj   +1 more source

Improving the quality of life of people with advanced breast cancer: a global expert review and call-to-action for 2025–2035 (goal 3)

Breast
Progress in the treatment landscape for advanced breast cancer (ABC) has significantly extended the survival of people with the disease. However, longevity alone is insufficient; maintaining and enhancing quality of life (QoL) is vital to ensure that ...
Karen Gelmon, Cynthia Villarreal-Garza, Dawn Aubel, Hope S. Rugo, Julia Maués, Luzia Travado, Matthijs Van Meerveld, Runcie C.W. Chidebe, Bianca Patel, Georgia Attfield, Alexandra Lewis, Fatima Cardoso   +11 more
doaj   +1 more source

A rim-enhanced mass with central cystic changes on MR imaging: how to distinguish breast cancer from inflammatory breast diseases?

PLoS ONE, 2014
ObjectiveTo evaluate the capacity of magnetic resonance imaging (MRI) to distinguish breast cancer from inflammatory breast diseases manifesting as a rim-enhanced mass with central cystic changes.Materials and methodsForty cases of breast cancer and 52 ...
Lijun Wang, Dengbin Wang, Xiaochun Fei, Mei Ruan, Weimin Chai, Lin Xu, Xiaoxiao Li   +6 more
doaj   +1 more source

Inflammatory breast cancer associated with amyopathic dermatomyositis: a case report

Surgical Case Reports, 2020
Background Dermatomyositis is associated with malignant tumors including breast cancer, and inflammatory breast cancer is considered to have a poorer prognosis than most breast cancers.
Gaku Inaguma, Akihiko Shimada, Junya Tsunoda, Tomohiko Matsuzaki, Tomohiko Nishi, Hiroaki Seki, Hidetoshi Matsumoto   +6 more
doaj   +1 more source

Mechanisms of resistance to lapatinib in HER2 positive breast cancer [PDF]

, 2012
Lapatinib is a tyrosine kinase inhibitor of HER2 which blocks downstream signaling pathways in HER2 positive breast cancer cell lines, tumor xenografts and HER2 positive breast cancer patients.
McDermott, Martina
core  

The role of genetic factors in breast cancer aetiology [PDF]

, 2010
Breast cancer is the most common cancer in women and is also the leading cause of cancermortality in women. There are several known risk factors for breast cancer including geneticfactors which account for at least 25% of the incidence of breast cancer ...
Hammond, Victoria Naomi
core  

Inflammatory breast cancer: Time to standardise diagnosis assessment and management, and for the joining of forces to facilitate effective research [PDF]

, 2015
We are grateful to the input of participants at both the first and second UK Inflammatory Breast Cancer Symposium, held in 2011 and 2013, respectively, and to Breast Cancer Campaign for sponsoring the second of these symposia.
E Rakha, Hanby, A M, Francis, A, V Speirs, Martin, S.G., Hanby, A.M., I O Ellis, L J Jones, Vinnicombe, S., Berditchevski, F., Rea, D, Jones, L.J., S G Martin, Martin, SG, Rea, D., Vinnicombe, S, Hanby, A. M., Jones, LJ, S Vinnicombe, Speirs, V., S Chan, Hanby, AM, Shaaban, A, Shaaban, A., D Rea, A Shaaban, Jones, L. J., Francis, A., F Berditchevski, A M Hanby, Berditchevski, F, Martin, S. G., Rakha, E, Ellis, I O, Ellis, I.O., Rakha, E., Chan, S, Ellis, IO, on behalf of the UK Inflammatory Breast Cancer Working group, Ellis, I. O., Speirs, V, Martin, S G, A Francis, Jones, L J, UK Inflammatory Breast Cancer Working group, Chan, S.   +45 more
core   +1 more source

XIAP overexpressing inflammatory breast cancer patients have high infiltration of immunosuppressive subsets and increased TNFR1 signaling targetable with Birinapant

Translational Oncology
Objective: To assess the expression pattern of X-linked inhibitor of apoptosis protein (XIAP), a cellular stress sensor, and delineate the associated changes in the tumor immune microenvironment (TiME) for prognostic value and new therapeutic targets in ...
Christophe Van Berckelaer, Steven Van Laere, Seayoung Lee, Michael A Morse, Joseph Geradts, Luc Dirix, Mark Kockx, François Bertucci, Peter Van Dam, Gayathri R Devi   +9 more
doaj   +1 more source

Correction to: Inflammatory breast cancer defined: proposed common diagnostic criteria to guide treatment and research

, 2022
Erratum for: Inflammatory breast cancer defined: proposed common diagnostic criteria to guide treatment and research. Jagsi R, Mason G, Overmoyer BA, Woodward WA, Badve S, Schneider RJ, Lang JE, Alpaugh M, Williams KP, Vaught D, Smith A, Smith K, Miller ...
Jagsi, R., Schneider, R.J., Smith, K., Miller, K.D., Badve, S., Williams, K. P., Lang, J. E., Miller, K. D., Overmoyer, B. A., Woodward, W.A., Vaught, D., Schneider, R. J., Alpaugh, M., Lang, J.E., Woodward, W. A., Mason, G., Smith, A., Williams, K.P., Overmoyer, B.A.   +18 more
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