Results 91 to 100 of about 2,794,554 (162)

AAD-2004, a potent spin trapping molecule and microsomal prostaglandin E synthase-1 inhibitor, shows safety and efficacy in a mouse model of ALS [PDF]

, 2010
While free radicals and inflammation constitute major routes of neuronal injury occurring in neurodegenerative diseases, neither antioxidants nor nonsteroidal anti-inflammatory drugs (NSAIDs) have shown significant efficacy in human clinical trials.
Sun Park, Jae Lee, Bok Yun, Jin Lee, Jin Shin, Young Lee, Joe Springer, Sun Son, Yong Lee, Byoung Gwag, Doo Im, Soo Byun, Woong Cho   +12 more
core  

Ghrelin Reduces Infiltrating Inflammatory Cells After Traumatic Brain Injury

, 2014
1 Broadside. Designed using Microsoft PowerPoint. 48"W x 36"H• Traumatic Brain Injury (TBI) pathophysiology has two injury phases: primary mechanical assault and secondary indirect injury.
D'Mello, Ryan H.
core  

Acidosis, Iron Dyshomeostasis and Inflammatory Injury. [PDF]

Int J Mol Sci
Ingrassia R, Ghio AJ, Garrick M.
europepmc   +1 more source

Inositol Metabolism Modulates Inflammatory Injury in Acute Pancreatitis via the ISYNA1-NETs Axis. [PDF]

J Inflamm Res
Han F, Liu X, Fan Y, Chen L, Shi X, Wang Y, Xiao W, Lu G, Wu K, Xia T, Zhuang J, Sun R.   +11 more
europepmc   +1 more source

RasGRP4 aggravates ischemia-reperfusion injury in diabetic kidneys by mediating communication between macrophages and T cells

JCI Insight
Diabetes mellitus (DM) is acknowledged as an independent risk factor for acute kidney injury. Ras guanine nucleotide-releasing protein-4 (RasGRP4) exerts a notable role in modulating immune-inflammatory responses and kidney disease progression in ...
Li Zhang, Zhanglong Wang, Yunqi Wu, Binshan Zhang, Zhongli Wang, Sisi Chen, Xuying Meng, Pei Yu, Saijun Zhou   +8 more
doaj   +1 more source

SKP2 Regulates Pulmonary Inflammatory Injury Triggered by Bacterial Infection Through p27-Mediated Degradation of FOXN3. [PDF]

MedComm (2020)
Yu J, Hu X, Wang H, Yu J, Jin L, Li Y, Zhou J, Zhu X, Moses EJ, Zheng C, Zhang Y, Li W.   +11 more
europepmc   +1 more source

Activation of the cGAS-STING Pathway by NETs Promotes Inflammatory Injury in Myocardial Ischemia-Reperfusion. [PDF]

J Inflamm Res
Jiang J, Wu H, Zhou L, Wu S, Li Y, Tang D.   +5 more
europepmc   +1 more source

Molecular mechanism of hydromorphone preconditioning in cerebral ischemia/reperfusion‑induced inflammatory injury. [PDF]

Int J Mol Med
Yao J, Huang Z, Li S, Lun M, Fan J.
europepmc   +1 more source

Metabolic-epigenetic axis in cardiovascular inflammatory injury: regulatory mechanisms and intervention strategies. [PDF]

Front Cardiovasc Med
Yu X, Cui C, He J, Guan X, Zhang Z.
europepmc   +1 more source

A WEEV 6K viroporin activates MLKL-dependent necroptosis to drive inflammatory injury. [PDF]

Cell Death Discov
Zhou Z, Wu P, Gao Z, Xia B.
europepmc   +1 more source