Results 61 to 70 of about 2,794,554 (162)

Mild hypothermia alone or in combination with anesthetic post-conditioning reduces expression of inflammatory cytokines in the cerebral cortex of pigs after cardiopulmonary resuscitation [PDF]

, 2010
Introduction: Hypothermia improves survival and neurological recovery after cardiac arrest. Pro-inflammatory cytokines have been implicated in focal cerebral ischemia/reperfusion in-jury.
Meybohm, Patrick, Zitta, Karina, Grünewald, Matthias Lars, Albrecht, Martin, Zacharowski, Kai, Lucius, Ralph, Hensler, Johannes, Bein, Berthold, Fösel, Nikola, Matthias Gruenewald, Martin Albrecht, Johannes Hensler, Karina Zitta, Kai D Zacharowski, Patrick Meybohm, Nikola Fösel, Berthold Bein, Ralph Lucius   +17 more
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Ferulic Acid Interferes with Radioactive Intestinal Injury Through the DJ-1-Nrf2 and Sirt1-NF-κB-NLRP3 Pathways

Molecules
Radiation-induced intestinal injury is a common complication of radiotherapy for abdominal and pelvic malignancies. Due to its rapid proliferation, the small intestine is particularly sensitive to radiation, making it a critical factor limiting treatment.
Xuemei Zhang, Haoyu Zhang, Mingyue Huang, Yu Mei, Changkun Hu, Congshu Huang, Huiting Zhang, Xue Wei, Yue Gao, Zengchun Ma   +9 more
doaj   +1 more source

Severity of lung injury in cyclooxygenase-2-deficient mice is dependent on reduced prostaglandin E-2 production [PDF]

, 2004
Levels of prostaglandin E-2 (PGE(2)), a potent inhibitor of fibroblast function, are decreased in the lungs of patients with pulmonary fibrosis, which has been shown to be because of limited expression of cyclooxygenase-2 (COX-2).
Martyn L. Foster, Rebecca J. Hodges, R. Gisli Jenkins, Geoffrey J. Bellingan, Bellingan, GJ, Laurent, GJ, Jenkins, RG, Bottoms, SE, Copeman, DM, Geoffrey J. Laurent, Foster, ML, Stephen L. Hart, Hodges, RJ, Wheeler-Jones, CPD, Robin J. McAnulty, McAnulty, RJ, Nanthakumar, CB, Stephen E. Bottoms, Caroline P.D. Wheeler-Jones, Carmel B. Nanthakumar, Hart, SL, Danielle M. Copeman   +21 more
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Controlled cortical impact and craniotomy induce strikingly similar profiles of inflammatory gene expression, but with distinct kinetics

Frontiers in Neurology, 2012
An immediate consequence of traumatic brain injury (TBI) is the induction of an inflammatory response. Mounting data suggest that inflammation is a major contributor to TBI-induced brain damage.
Mouna eLagraoui, Joseph R. Latoche, Natalia G. Cartwright, Gauthaman eSukumar, Clifton L. Dalgard, Brian C. Schaefer   +5 more
doaj   +1 more source

Antigen - presentation by vascular endothelium : its role for CTL - mediated vascular injury [PDF]

, 2008
Background: EC express and present MHC class I restricted peptide antigens and due to the exposed position may be targeted by antigen-specific CTL. We wished to explore the type of vascular injury that is mediated by peptidespecific CTL in vivo when EC ...
Wang, Xueya
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Inflammation and Inflammatory Cells in Myocardial Infarction and Reperfusion Injury: A Double-Edged Sword

, 2016
Myocardial infarction (MI) is the most common cause of cardiac injury, and subsequent reperfusion further enhances the activation of innate and adaptive immune responses and cell death programs.
Haijuan Wang, Jun Li, Jiaqi Liu
core   +1 more source

Effect of Intravenous Lidocaine on Inflammatory and Apoptotic Response of Ischemia-Reperfusion Injury in Pigs Undergoing Lung Resection Surgery

, 2021
Background: Ischemia-reperfusion injury is one of the most critical phenomena in lung transplantation and causes primary graft failure. Its pathophysiology remains incompletely understood, although the inflammatory response and apoptosis play key roles ...
Romero Gómez, Bárbara, Cebollero, Sara, Zapatero, Sara, Simón Adiego, Carlos María, Simón, Carlos, Romera, Andrea, García-Aldao, Uxío, Carricondo, Francisco, Garutti, Ignacio, Romero-Gómez, Bárbara, Vara Ameigeiras, Elena María, Ortega, Javier, Vara, Elena, Carricondo Orejana, Francisco Javier, Martín-Albo, Lorena, Cebollero, María, Lorena Martín-Albo, Javier Ortega, Ignacio Garutti, Andrea Romera, Francisco Carricondo, Sara Zapatero, Carlos Simón, Elena Vara, Bárbara Romero-Gómez, Uxío García-Aldao, María Cebollero   +26 more
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Dopamine promotes Klebsiella quasivariicola proliferation and inflammatory response in the presence of macrophages

Frontiers in Cellular and Infection Microbiology
BackgroundDopamine, a frequently used therapeutic agent for critically ill patients, has been shown to be implicated in clinical infections recently, however, the precise mechanisms underlying this association remain elusive. Klebsiella quasivariicola, a
Xiang Li, Xiang Li, Lin Cheng, Xueyang Liu, Xueyang Liu, Xiaoli Wang, Rui Li, Shao Fan, Qiulong Yan, Tonghui Ma, Yufang Ma, Jian Kang   +11 more
doaj   +1 more source

Inflammation and blood-brain barrier breach remote from the primary injury following neurotrauma

Journal of Neuroinflammation, 2018
Background Following injury to the central nervous system, increased microglia, secretion of pro- and anti-inflammatory cytokines, and altered blood-brain barrier permeability, a hallmark of degeneration, are observed at and immediately adjacent to the ...
Nicole M. Smith, Marcus K. Giacci, Alexander Gough, Charlotte Bailey, Terence McGonigle, Anna M. B. Black, Thomas O. Clarke, Carole A. Bartlett, K. Swaminathan Iyer, Sarah A. Dunlop, Melinda Fitzgerald   +10 more
doaj   +1 more source

Intestinal inflammatory and oxidative injury mediators in each group.

, 2016
Intestinal inflammatory and oxidative injury mediators in each group.
Lianyang Zhang (3079899), Yang Li (7082), Mingtao Chang (3079902), Hao Tang (44155), Dong Liu (115204)   +4 more
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