Results 51 to 60 of about 5,026,038 (351)

TRPV4-A Missing Link Between Mechanosensation and Immunity [PDF]

open access: yes, 2020
Transient receptor potential vanilloid-type 4 (TRPV4) cation channel is widely expressed in all tissues as well as in immune cells and its function as mechanosensitive Ca2+ channel seems to be conserved throughout all mammalian species. Of late, emerging
Kuebler, Wolfgang M., Michalick, Laura
core   +1 more source

The involvement of miR-6615-5p/Smad7 axis and immune imbalance in ammonia-caused inflammatory injury via NF-κB pathway in broiler kidneys

open access: yesPoultry Science, 2020
Ammonia (NH3), a toxic gas, has deleterious effects on chicken health in intensive poultry houses. MicroRNA can mediate inflammation. The complex molecular mechanisms underlying NH3 inhalation–caused inflammation in animal kidneys are still unknown.
Qi Han   +5 more
doaj   +1 more source

Lactobacillus salivarius WZ1 Inhibits the Inflammatory Injury of Mouse Jejunum Caused by Enterotoxigenic Escherichia coli K88 by Regulating the TLR4/NF-κB/MyD88 Inflammatory Pathway and Gut Microbiota

open access: yesMicroorganisms, 2023
Replacing antibiotics with probiotics has become an important way to safely and effectively prevent and treat some gastrointestinal diseases. This study was conducted to investigate whether Lactobacillus salivarius WZ1 (L.S) could reduce the inflammatory
Zhen Wei   +5 more
doaj   +1 more source

A Single Dose of Atorvastatin Applied Acutely after Spinal Cord Injury Suppresses Inflammation, Apoptosis, and Promotes Axon Outgrowth, Which Might Be Essential for Favorable Functional Outcome. [PDF]

open access: yes, 2018
The aim of our study was to limit the inflammatory response after a spinal cord injury (SCI) using Atorvastatin (ATR), a potent inhibitor of cholesterol biosynthesis.
Bacova, Maria   +11 more
core   +2 more sources

Palmitic Acid and β-Hydroxybutyrate Induce Inflammatory Responses in Bovine Endometrial Cells by Activating Oxidative Stress-Mediated NF-κB Signaling

open access: yesMolecules, 2019
Ketosis is a nutritional metabolic disease in dairy cows, and researches indicated that ketonic cows always accompany reproductive problems. When ketosis occurs, the levels of non-esterified fatty acids (NEFAs) and β-hydroxybutyrate (BHBA) in the ...
Peng Li   +8 more
doaj   +1 more source

Circ_0038467 regulates lipopolysaccharide‐induced inflammatory injury in human bronchial epithelial cells through sponging miR‐338‐3p

open access: yesThoracic Cancer, 2020
Background Pneumonia is a common acute lower respiratory infection in children and elders. Circular RNAs (circRNAs) have recently been uncovered to play important roles in pneumonia. However, the function and mechanism of circ_0038467 in pneumonia remain
Guangming Liu   +5 more
doaj   +1 more source

An Inflammation-Centric View of Neurological Disease: Beyond the Neuron [PDF]

open access: yes, 2018
Inflammation is a complex biological response fundamental to how the body deals with injury and infection to eliminate the initial cause of cell injury and effect repair.
Facci, Laura   +3 more
core   +2 more sources

Treating Macrophages with Anti-inflammatory Nanoparticles as a Strategy to Improve Muscle Repair [PDF]

open access: yes, 2019
The macrophage is an immune cell that is involved in host defense. More recent research, however, has revealed that they also play a central role in mediating the skeletal muscle regenerative process.
Yan, Derek
core   +1 more source

Involvement of leukotriene pathway in the pathogenesis of ischemia-reperfusion injury and septic and non-septic shock. [PDF]

open access: yes, 2009
The 5-lipoxygenase (5-LO) pathway is responsible for the production of leukotrienes (LTs), inflammatory lipid mediators which play a role in innate immunity. More recently, a pivotal role of LTs in ischemia-reperfusion and shock injury has been suggested.
CUZZOCREA S   +2 more
core   +1 more source

Electronic cigarette exposure on insulin sensitivity of ApoE gene knockout mice

open access: yesTobacco Induced Diseases, 2020
Introduction The current study aimed to investigate the effects of electronic cigarettes on insulin sensibility in ApoE gene knockout mice. Methods In total, 48 male ApoE gene knockout mice were randomly divided into four exposure groups: 1) electronic ...
Kai Lan+   +7 more
doaj   +1 more source

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