Results 51 to 60 of about 1,347,839 (304)

Enteropathogenic E. coli shows delayed attachment and host response in human jejunum organoid‐derived monolayers compared to HeLa cells

FEBS Letters, EarlyView.
Enteropathogenic E. coli (EPEC) infects the human intestinal epithelium, resulting in severe illness and diarrhoea. In this study, we compared the infection of cancer‐derived cell lines with human organoid‐derived models of the small intestine. We observed a delayed in attachment, inflammation and cell death on primary cells, indicating that host ...
Mastura Neyazi, Pilar Samperio Ventayol, Natalie Burkard, Nicolas Schlegel, Carmen Aguilar, Sina Bartfeld   +5 more
wiley   +1 more source

Are cytokines (IL-6, CRP and adiponectin) associated with bone mineral density in a young adult birth cohort?

BMC Musculoskeletal Disorders, 2018
Background Studies have shown that cytokines play a role in bone remodeling. Methods In 1993, all hospital births occurred in Pelotas (Brazil) were identified and a total of 5249 newborns were included in the present cohort.
Ana Maria Baptista Menezes, Paula Duarte Oliveira, Helen Gonçalves, Isabel O. Oliveira, Maria Cecilia F. Assunção, Luciana Tovo-Rodrigues, Gustavo Dias Ferreira, Fernando César Wehrmeister   +7 more
doaj   +1 more source

Backbone switch to abacavir/lamivudine fixed-dose combination: implications for antiretroviral therapy optimization [PDF]

, 2015
Current guidelines recommend treatment optimization in virologically suppressed patients through switching/ simplification strategies to minimize long-term toxicities and improve adherence. The assessment of inflammation/ coagulation profiles may support
FALASCA, FRANCESCA, FANTAUZZI, Alessandra, Floridia, Marco, MEZZAROMA, Ivano, SPANEDDA, Pierpaolo, TURRIZIANI, Ombretta, VULLO, Vincenzo   +6 more
core  

Microbial risk factors of cardiovascular and cerebrovascular diseases: potential therapeutic options [PDF]

, 2008
Infection and inflammation may have a crucial role in the pathogenesis of atherosclerosis. This hypothesis is supported by an increasing number of reports on the interaction between chronic infection, inflammation, and atherogenesis.
Abbas, M.A., Comi, G, Corea, F, Fawi, G, Galantucci, S, Guenther, A, Kwan, Joseph W.   +6 more
core   +1 more source

Reciprocal control of viral infection and phosphoinositide dynamics

FEBS Letters, EarlyView.
Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley   +1 more source

Post-ride inflammatory markers in endurance horses

Ciência Rural, 2016
: The acute phase reaction occurs in response to diseases, surgical trauma and can happen after strenuous exercise, like long distance events. This study aimed to evaluate the Serum Amyloid A (SAA), pro-inflammatory interleukins (IL-1β and TNFα) and ...
Renata Farinelli de Siqueira, Wilson Roberto Fernandes   +1 more
doaj   +1 more source

By dawn or dusk—how circadian timing rewrites bacterial infection outcomes

FEBS Letters, EarlyView.
The circadian clock shapes immune function, yet its influence on infection outcomes is only beginning to be understood. This review highlights how circadian timing alters host responses to the bacterial pathogens Salmonella enterica, Listeria monocytogenes, and Streptococcus pneumoniae revealing that the effectiveness of immune defense depends not only
Devons Mo, Catherine S. Palmer, Jacqueline M. Kimmey   +2 more
wiley   +1 more source

Clinic, Anthropometric And Metabolic Changes In Adults With Class III Obesity Classified As Metabolically Healthy And Metabolically Unhealthy

Diabetes, Metabolic Syndrome and Obesity, 2019
Ligiane M Loureiro,1–3 Adryana Cordeiro,3,4 Rodrigo Mendes,5 Mariana Luna,3 Sílvia Pereira,3,6 Carlos J Saboya,3,6 Andrea Ramalho3,7 1Postgraduate Program, Doctorate in Nutritional Sciences, Federal University of Rio de Janeiro (UFRJ), Rio ...
Loureiro LM, Cordeiro A, Mendes R, Luna M, Pereira S, Saboya CJ, Ramalho A   +6 more
doaj  

Interplay between circadian and other transcription factors—Implications for cycling transcriptome reprogramming

FEBS Letters, EarlyView.
This perspective highlights emerging insights into how the circadian transcription factor CLOCK:BMAL1 regulates chromatin architecture, cooperates with other transcription factors, and coordinates enhancer dynamics. We propose an updated framework for how circadian transcription factors operate within dynamic and multifactorial chromatin landscapes ...
Xinyu Y. Nie, Jerome S. Menet
wiley   +1 more source

Evaluation of Plasma Selenium Level and its Association with Malnutrition in Hemodialysis Patients in Golestan Province, Iran

Journal of Clinical and Basic Research, 2017
Introduction: Selenium (Se) is a rare element with well-demonstrated anti-oxidative effects that acts as an enzyme co-factor in physiological interactions.
Saeed Amirkhanlou, Hassan Emadi, Anna rashedi, Samira Eshghinia   +3 more
doaj   +2 more sources