A Neural Circuit from the Pedunculopontine Tegmental Nucleus to the Central Medial Thalamic Nucleus for the Regulation of Nociceptive and Anxiety-like Behaviors in Male Mice with Chronic Inflammatory Pain. [PDF]
Gao SJ +12 more
europepmc +1 more source
Targeting prostaglandin E<sub>2</sub> receptor 2 in Schwann cells inhibits inflammatory pain but not inflammation. [PDF]
Nassini R +23 more
europepmc +1 more source
Characterization of acupuncture on central amino acid metabolism based on targeted neurotransmitter analysis in mice with inflammatory pain. [PDF]
Yue W +8 more
europepmc +1 more source
Inflammatory pain in mice induces light cycle-dependent effects on sleep architecture. [PDF]
Burek DJ +7 more
europepmc +1 more source
Structural modification of 5-alkyl-4-phenyl-thiazole-based fatty acid amide hydrolase and soluble epoxide hydrolase inhibitors to alleviate orofacial inflammatory pain in the rat. [PDF]
Gorostiza G +11 more
europepmc +1 more source
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Prostanoids and inflammatory pain
Prostaglandins and Other Lipid Mediators, 2013Prostanoids play pivotal roles in inflammation and pain. Cyclooxygenase (COX) inhibitors, the nonsteroidal anti-inflammatory drugs (NSAIDs), depress prostanoid formation and are widely used to treat inflammatory pain. However, their therapeutic benefit is offset by serious side-effects, primarily gastrointestinal and cardiovascular complications ...
Lihong Chen, Tilo Grosser, Guangrui Yang
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Bradykinin and inflammatory pain
Trends in Neurosciences, 1993There is compelling evidence linking bradykinin (BK) with the pathophysiological processes that accompany tissue damage and inflammation, especially the production of pain and hyperalgesia. Several mechanisms have been proposed to account for hyperalgesia including the direct activation of nociceptors as well as sensitization of nociceptors through the
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Traditionally, non-steroidal anti-inflammatory drugs (NSAIDs) have been advocated for inflammatory pain. Studies in arthritic rats have shown that inflammatory pain is more sensitive to opioids than other types of nociceptive pain.
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Inflammatory pain: kinins and antagonists
Current Opinion in Anaesthesiology, 2001This short review focuses on the most recent findings in the rapidly expanding field of kinin research. Through a series of recent publications, the crucial relevance of this group of peptides as mediators of inflammatory pain is becoming increasingly evident.
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