Results 111 to 120 of about 58,972 (283)

Decreased clinical response to infliximab in ankylosing spondylitis is correlated with anti-infliximab formation

, 2007
OBJECTIVES: Correlation of serum trough infliximab levels and antibodies to infliximab (anti-infliximab) with clinical response in ankylosing spondylitis. METHODS: In accordance with the international ASsessment in Ankylosing Spondylitis (ASAS) consensus
de Vries, Mirjam K., Aarden, Lucien A., van Denderen, J. Christiaan, Dijkmans, Ben A. C., van der Horst-Bruinsma, Irene E., de Vrieze, Henk, Stapel, Steven O., Wolbink, Gerrit Jan   +7 more
core   +1 more source

Multi‐omics biomarkers for intestinal infection and inflammation in inflammatory bowel disease: Current evidence, translational challenges, and diagnostic opportunities

Interdisciplinary Medicine, EarlyView.
Prospective multi‐site cohorts, multi‐omics profiling, and computational analysis may help identify biomarker patterns across clinical settings in IBD and superimposed infections. With further mechanistic and clinical validation, these signals could support the development of practical multi‐analyte tools for more precise diagnosis and management ...
Ziyu Yang, Jiayi Yao, Xinxian Zhao, Yan Xu, Yifan Chen, Tianchi Chen, Ying Jian, Min Li   +7 more
wiley   +1 more source

Mucosal healing did not predict sustained clinical remission in patients with IBD after discontinuation of one-year infliximab therapy.

PLoS ONE, 2014
AimTo assess the endoscopic activity and Clinical activity after a one-year period of infliximab therapy and to evaluate the association between mucosal healing and need for retreatment after stopping infliximab in patients with Inflammatory bowel ...
Cong Dai, Wei-Xin Liu, Min Jiang, Ming-Jun Sun   +3 more
doaj   +1 more source

Treatment of severe psoriasis with infliximab

, 2008
JA Leman, AD BurdenAlan Lyell Centre for Dermatology, Western Infirmary, Glasgow, UKAbstract: Psoriasis is a chronic, immune mediated inflammatory disease characterized by increased cell signalling via cytokines and chemokines on a background of up ...
AD Burden, JA Leman
core  

Deep learning‐assisted design of nanozyme for immune regulation

Journal of Intelligent Medicine, EarlyView.
Overview of nanozyme‐based strategies for inflammatory bowel disease therapy, featuring metal‐based and non‐metallic nanozymes classified by structure, alongside multifunctional and engineered probiotic‐based nanozymes classified by function. Abstract Inflammatory bowel disease (IBD), with rising global incidence and disease burden, is a multifactorial
Ke Chen, Si Sun, Shaofang Zhang, Huanhuan Qiao   +3 more
wiley   +1 more source

Subcutaneous administration of infliximab-attenuated silica-induced lung fibrosis

, 2017
Objectives To investigate the influence of the anti-tumor necrosis factor-α infliximab (IFX) in the case of rats with silicosis. Material and Methods Forty-eight Wistar rats were randomly divided into 3 groups.
Gao, Lei, Guo, Jian, Jian Guo, Hua Zhang, Sui, Jun-Na, Zhang, Hua, Jun-Na Sui, Lei Gao   +7 more
core   +1 more source

Evaluating the impact of therapeutic drug monitoring strategies on clinical outcomes in paediatric inflammatory bowel disease

Journal of Pediatric Gastroenterology and Nutrition, EarlyView.
Abstract Objectives The increasing incidence of inflammatory bowel disease (IBD) in paediatric populations underscores the importance of effective management strategies. Anti–tumor necrosis factor (anti‐TNF) agents, such as infliximab (IFX) and adalimumab (ADL), are key treatments for inducing and maintaining remission in IBD, but many patients ...
Karlotta Pauline Hubert, Sebastian Stricker, Jan De Laffolie   +2 more
wiley   +1 more source

Profile of infliximab in the treatment of pediatric Crohn’s disease

, 2015
Jaroslaw Kierkus,1 Edyta Szymanska,2 Grzegorz Oracz,1 Anna Wiernicka,1 Maciej Dadalski1 1Department of Gastroenterology, Hepatology, Feeding Disorders and Pediatrics, 2Department of Pediatrics, Nutrition and Metabolic Disorders, The Children’s ...
Szymanska E, Oracz G, Dadalski M, Wiernicka A, Kierus J   +4 more
core  

Upper and small bowel Crohn's disease in Brazilian children: Phenotypic characteristic and surgical risk

Journal of Pediatric Gastroenterology and Nutrition, EarlyView.
Abstract Objectives Upper and small bowel Crohn's disease (U‐SBCD) represents a clinically aggressive phenotype with high complication rates yet remains diagnostically challenging. In low‐ and middle‐income countries (LMICs), limited inflammatory bowel disease (IBD) awareness contributes to diagnostic delays, but their impact on U‐SBCD outcomes remains
Jane Oba, Carlos Walter Sobrado, Elizete Aparecida Lomazi, Mariana Deboni, Michela Cynthia da Rocha Marmo, Vanessa Adriana Scheeffer, Silvio da Rocha Carvalho, Adérson Omar Mourão Cintra Damião, Matheus Freitas Cardoso de Azevedo, Carlos Frederico Sparapan Marques, Eytan Wine, Artur Figueiredo Delgado, Clovis Artur Almeida da Silva Full   +12 more
wiley   +1 more source

Topical infliximab for the suppression of wound healing following experimental glaucoma filtration surgery

, 2014
Burak Turgut,1 Kenan Eren,1 Mehmet Mustafa Akin,2 Tamer Demir,1 Sabiha Kobat1 1Department of Ophthalmology, School of Medicine, Firat University, Elaziğ, Turkey; 2Department of Pathology, School of Medicine, Firat University, Elaziğ, Turkey Background ...
Turgut B, Akın MM, Kobat S, Eren K, Demir T   +4 more
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