Results 121 to 130 of about 58,972 (283)

INFLIXIMAB FOR REFRACTORY ULCERATIVE PROCTITIS

, 2010
International audienceBackground: Efficacy of infliximab in treating ulcerative proctitis is unknown. Aim: To evaluate clinical, biological and endoscopic efficacy of infliximab therapy in refractory proctitis. Methods: The charts of 420 patients treated
Bouguen, Guillaume, Siproudhis, Laurent, Flourie, Bernard, Roblin, Xavier, Hebuterne, Xavier, Feier, Laura, Nancey, Stéphane, Bretagne, Jean-François, Bourreille, Arnaud, Filippi, Jérôme, Peyrin-Biroulet, Laurent, Bigard, Marc-André   +11 more
core   +1 more source

Impact of 5‐ASA discontinuation in children with ulcerative colitis on biologic therapy: A propensity score‐matched study

Journal of Pediatric Gastroenterology and Nutrition, EarlyView.
Abstract Objectives 5‐Aminosalicylic acid (5‐ASA) is recommended as a first‐line medication in mild to moderate ulcerative colitis (UC), but indications regarding its use in children with moderate to severe disease treated with biologics are lacking.
Giulia D'Arcangelo, Luca Scarallo, Giulia Mancuso, Mara Corpino, Claudio Romano, Lorenzo Norsa, Serena Arrigo, Matteo Bramuzzo, Maria Teresa Fioretti, Giovanna Zuin, Maria Teresa Illiceto, Paolo Lionetti, Marina Aloi   +12 more
wiley   +1 more source

Clinical experience with infliximab administration in patients with rheumatoid arthritis by Russian register data

Терапевтический архив, 2009
Aim. To analyse the data on infliximab administration (efficacy, tolerance, toxicity) in patients with rheumatoid arthritis (RA) in Russia by clinical evidence provided by the multicenter observation trial. Material and methods. The register included 297
Galina Viktorovna Lukina, Yakov Aleksandrovich Sigidin, Evgeniy L'vovich Nasonov, G V Lukina, Ya A Sigidin, E L Nasonov   +5 more
doaj  

Infliximab dose adjustment can improve the clinical and radiographic outcomes of rheumatoid arthritis patients: REVIVE study results

, 2018
Yuji Nozaki, Yasuaki Nagare, Chisato Ashida, Daisuke Tomita, Akinori Okada, Asuka Inoue, Koji Kinoshita, Masanori Funauchi, Itaru Matsumura Department of Hematology and Rheumatology, Kindai University School of Medicine, Osaka, Japan Purpose: We ...
Kinoshita K, Ashida C, Matsumura I, Inoue A, Nozaki Y, Funauchi M, Okada A, Tomita D, Nagare Y   +8 more
core  

Long‐term outcomes of children with ulcerative colitis after acute severe colitis: A GETAID pédiatrique multicenter study

Journal of Pediatric Gastroenterology and Nutrition, EarlyView.
Abstract Objectives Acute severe colitis (ASC) is a frequent and severe complication of ulcerative colitis (UC) with a high risk of colectomy. Effects of immunosuppressants and anti–tumor necrosis factor (anti‐TNF) agents on the risk of colectomy remain debated. We wished to study the evolution of French pediatric‐onset UC patients after ASC.
Manon Cochet, Agathe Beauvais, Frank Ruemmele, Raphael Enaud, Thierry Lamireau, Rémi Duclaux‐Loras, Claire Dupont, Stéphanie Willot, Laure Bridoux‐Henno, Georges Dimitrov, Julie Lemale, Vincent Guinard‐Samuel, Valérie Bertrand, Anne Breton, Christine Martinez Vinson, Stéphanie Coopman, Delphine Ley, Bénédicte Pigneur, and the Groupe d'Etudes Thérapeutiques des Affections Inflammatoires du tube Digestif (GETAID) pédiatrique   +18 more
wiley   +1 more source

Bowel ultrasound scan in the management of pediatric moderate ulcerative colitis: The applicability of international bowel ultrasound segmental activity score

Journal of Pediatric Gastroenterology and Nutrition, EarlyView.
Abstract Objectives To evaluate bowel ultrasound (BUS) findings and the diagnostic and prognostic performance of international bowel ultrasound segmental activity score (IBUS‐SAS) in children with moderate ulcerative colitis (UC), including its accuracy for assessing endoscopic activity and predicting clinical remission and colectomy within 12 months ...
Martina Di Benedetto, Luca Scarallo, Camilla Pannacci, Sara Renzo, Monica Paci, Sara Naldini, Jacopo Barp, Laura Tasciotti, Paolo Lionetti   +8 more
wiley   +1 more source

A case report of Peutz–Jeghers syndrome in a child with Crohn's disease

JPGN Reports, EarlyView.
Abstract Peutz–Jeghers syndrome (PJS) is a rare genetic disorder characterized by hamartomatous polyps and mucocutaneous hyperpigmented freckles, whereas Crohn's disease (CD) is a condition characterized by chronic intestinal inflammation. Here, we present a rare case report of an 11‐year‐old male who presented with both CD and PJS.
Hasala Rannulu, Eve May, Bethany Cunningham, Eric Cochran, Rachel Zdenek, Stefany H. Garrity   +5 more
wiley   +1 more source

The safe and effective use of tofacitinib and ustekinumab combination therapy in infantile onset inflammatory bowel disease

JPGN Reports, EarlyView.
Abstract Infantile‐onset inflammatory bowel disease (IOIBD) is a rare and severe subset of very‐early‐onset IBD, often associated with immune dysregulation and poor response to conventional therapies. Data regarding the use of Janus kinase inhibitors (JAKI) in this population is limited.
Smridhi Mahajan, Christian Wysocki, Bhaskar Gurram   +2 more
wiley   +1 more source

Effect of a continuous measure of adherence with infliximab maintenance treatment on inpatient outcomes in Crohn's disease

, 2012
Chureen T Carter,1 Heidi C Waters,1 Daniel B Smith21Health Economics and Outcomes Research, Janssen Scientific Affairs, LLC, Horsham, PA, USA; 2Statistics, IMS Health, Watertown, MA, USABackground: To assess the impact of a continuous measure of ...
Carter CT, Smith DB, Waters HC
core  

Pyoderma Gangrenosum: A Retrospective Cohort Study of Comorbidities and Therapies in Over 65,000 Patients in the TriNetX Database

JEADV Clinical Practice, EarlyView.
ABSTRACT Background Pyoderma gangrenosum (PG) is a rare neutrophilic dermatosis associated with systemic inflammatory diseases and malignancy. Although biologic therapies demonstrate efficacy in PG, the extent of their real‐world use remains incompletely characterized.
Rhiannon Grange, Tara Sholji, Marra Aghajani, Cindy Kok, John Frew   +4 more
wiley   +1 more source