Results 131 to 140 of about 91,870 (284)
Cause for controversy? Infliximab in the treatment of ulcerative colitis: an update
Clinical and Experimental Gastroenterology, 2009 Garrett Lawlor, Alan C MossBeth Israel Deaconess Medical Center and Harvard Medical School, Boston, MA, USAAbstract: Infliximab is a monoclonal antibody against tumor necrosis factor (TNF) which has become an established therapy for Crohn’s ...
Garrett Lawlor, Alan C Moss
doaj
Azathioprine-Induced Peripheral T Cell Apoptosis And Drug Response In Patients With Crohn’s Disease [PDF]
, 2011 Background and Aim: the long time interval for a trial of thioupurine therapy and the potential side effects in spite of the proven efficacy, do not encourage their use as early therapeutic option in Crohn’s Disease (CD).
Cossu, Andrea
core
Observational study of metastatic vulvar Crohn's disease in the pediatric population
JPGN Reports, EarlyView.Abstract Objective Metastatic vulvar Crohn's disease (MVCD) is a rare cutaneous manifestation of Crohn's disease (CD), especially in pediatric patients. The objective of this study is to assess presentation, diagnosis, and treatment for pediatric MVCD in the largest cohort reported. Methods This is a retrospective review of pediatric patients with MVCD
Deborah Winograd +6 more
wiley +1 more source
JPGN Reports, EarlyView.Abstract The annual healthcare spending on pediatric inflammatory bowel disease (IBD) has increased over time. The objectives of the study were to investigate the cost of routine laboratory surveillance in pediatric IBD patients during outpatient maintenance biologic infusions and determine their impact on clinical management.
Tanmai Shah +3 more
wiley +1 more source
Efficacy of upadacitinib induction for pediatric inflammatory bowel disease
JPGN Reports, EarlyView.Abstract Objectives Upadacitinib, a second‐generation Janus kinase (JAK) inhibitor, is approved for moderate to severe Crohn's disease (CD) and ulcerative colitis (UC) in adults. Its efficacy in pediatric patients remains unclear, though early reports suggest benefits in refractory inflammatory bowel disease (IBD).
Evan Greenhall +5 more
wiley +1 more source
JPGN Reports, EarlyView.Abstract Skin and lung findings, including the rare findings of leukocytoclastic vasculitis (LCV) and necrobiotic pulmonary nodules, are known extraintestinal manifestations (EIMs) of inflammatory bowel disease. However, these rare EIMs have typically been reported as being a sign of active intestinal disease.
Joshua D. Noe +3 more
wiley +1 more source
JPGN Reports, EarlyView.Abstract Crohn's disease (CD) and eosinophilic gastrointestinal diseases (EGIDs) are distinct inflammatory entities, but eosinophilic disease may emerge as a paradoxical immune complication of anti–tumor necrosis factor therapy. We report a 12‐year‐old boy with terminal ileal CD who developed severe eosinophilic gastritis and ileitis, peripheral ...
Jonathan Dudzik +3 more
wiley +1 more source
A case report of Peutz–Jeghers syndrome in a child with Crohn's disease
JPGN Reports, EarlyView.Abstract Peutz–Jeghers syndrome (PJS) is a rare genetic disorder characterized by hamartomatous polyps and mucocutaneous hyperpigmented freckles, whereas Crohn's disease (CD) is a condition characterized by chronic intestinal inflammation. Here, we present a rare case report of an 11‐year‐old male who presented with both CD and PJS.
Hasala Rannulu +5 more
wiley +1 more source
Surgical Reconstruction in Pyoderma Gangrenosum, a Retrospective Study of Five Patients
JEADV Clinical Practice, EarlyView.ABSTRACT Pyoderma Gangrenosum (PG) is a neutrophilic dermatosis characterized by chronic painful ulcerations most commonly on the lower extremities. Current treatment options for PG are largely nonsurgical and include the use of systemic and topical immunomodulators and wound care.
Max E. Oscherwitz +8 more
wiley +1 more source
Successful treatment of therapy-resistant metastatic Crohn's desiase with infliximab [PDF]
, 2004 CASTIGLIONE, FABIANA +5 more
core +1 more source