Results 101 to 110 of about 145,258 (308)

An upstream open reading frame regulates expression of the mitochondrial protein Slm35 and mitophagy flux

FEBS Letters, EarlyView.
This study reveals how the mitochondrial protein Slm35 is regulated in Saccharomyces cerevisiae. The authors identify stress‐responsive DNA elements and two upstream open reading frames (uORFs) in the 5′ untranslated region of SLM35. One uORF restricts translation, and its mutation increases Slm35 protein levels and mitophagy.
Hernán Romo‐Casanueva, Ariann E. Mendoza‐Martínez, P. Abril Medina‐Flores, Carlos Campero‐Basaldua, Alexander DeLuna, Soledad Funes   +5 more
wiley   +1 more source

Influencers no humanos en Instagram: entre el posfeminismo y el transhumanismo [PDF]

Aposta
Desde 2016 viene creciendo la popularidad de influencers no humanos. Junto con la industria del marketing de influencers también proliferan investigaciones académicas que plantean diferentes preguntas sobre influencers humanos y no humanos y la relación ...
Romina Andrea Barboza
doaj  

Migrant Social Media Influencers as Vernacular CERC Agents: Mediating Government Communication During Covid-19

Media and Communication
Effective government communication is crucial for promoting inclusive governance, especially in increasingly diverse societies. However, a significant gap remains in engaging residents with migration backgrounds, often leaving these communities ...
Anna Smoliarova
doaj   +1 more source

Crisis Communications: How Businesses Respond in the Wake of Tragedy [PDF]

, 2019
Crisis communication is an ever-evolving form of communication that is integral to a business’s success. When tragedy strikes, businesses must have a thorough plan of response that manages the situation and protects their brand.
Blow, Sarah
core   +1 more source

Sequence determinants of RNA G‐quadruplex unfolding by Arg‐rich regions

FEBS Letters, EarlyView.
We show that Arg‐rich peptides selectively unfold RNA G‐quadruplexes, but not RNA stem‐loops or DNA/RNA duplexes. This length‐dependent activity is inhibited by acidic residues and is conserved among SR and SR‐related proteins (SRSF1, SRSF3, SRSF9, U1‐70K, and U2AF1).
Naiduwadura Ivon Upekala De Silva, Puspa Kunwar, Md Ibnul Rifat Rahman, Joanna Koryo Kwao, Nathan Lehman, Zihan Zhang, Trenton Paul, Claire Cheng, Nicholas Truex, Hui‐Ting Lee, Jun Zhang   +10 more
wiley   +1 more source

Structural instability impairs function of the UDP‐xylose synthase 1 Ile181Asn variant associated with short‐stature genetic syndrome in humans

FEBS Letters, EarlyView.
The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li, Pedro A. Sánchez‐Murcia, Bernd Nidetzky   +2 more
wiley   +1 more source

Perceptions, Trust and Action: The Role of Demographics in Shaping Influencer Impact

Management
Research Question: How do demographic characteristics shape audience perceptions, trust levels, and behaviour regarding influencers? Motivation: Although the role of influencers in shaping consumer behaviour has been widely studied, there has been ...
Bojana Pavlović, Jelena Krstić, Tamara Vlastelica   +2 more
doaj   +1 more source

PICALM::MLLT10 translocated leukemia

FEBS Letters, EarlyView.
This comprehensive review of PICALM::MLLT10 translocated acute leukemia provides an in‐depth review of the structure and function of CALM, AF10, and the fusion oncoprotein (1). The multifaceted molecular mechanisms of oncogenesis, including nucleocytoplasmic shuttling (2), epigenetic modifications (3), and disruption of endocytosis (4), are then ...
John M. Cullen, Antonia C. Nakatsugawa, Natalie Barton, Henry Haines, Gary S. Stein, Janet L. Stein, Daniel S. Wechsler, Jessica L. Heath   +7 more
wiley   +1 more source

Inhibiting stearoyl‐CoA desaturase suppresses bone metastatic prostate cancer by modulating cellular stress, mTOR signaling, and DNA damage response

FEBS Letters, EarlyView.
Bone metastasis in prostate cancer (PCa) patients is a clinical hurdle due to the poor understanding of the supportive bone microenvironment. Here, we identify stearoyl‐CoA desaturase (SCD) as a tumor‐promoting enzyme and potential therapeutic target in bone metastatic PCa.
Alexis Wilson, Mackenzie K Herroon, Shane Mecca, Laimar C Garmo, Jacob Lindquist, Shrila Rajendran, Steve M. Patrick, Izabela Podgorski   +7 more
wiley   +1 more source

Effects of Time Horizons on Influence Maximization in the Voter Dynamics

, 2018
In this paper we analyze influence maximization in the voter model with an active strategic and a passive influencing party in non-stationary settings. We thus explore the dependence of optimal influence allocation on the time horizons of the strategic ...
Brede, Markus, Restocchi, Valerio, Stein, Sebastian   +2 more
core   +1 more source