Results 51 to 60 of about 8,955,500 (341)

Alarming situation of emerging H5 and H7 avian influenza and effective control strategies

Emerging Microbes and Infections, 2022
Avian influenza viruses continue to present challenges to animal and human health. Viruses bearing the hemagglutinin (HA) gene of the H5 subtype and H7 subtype have caused 2634 human cases around the world, including more than 1000 deaths.
Jianzhong Shi, Xianying Zeng, Pengfei Cui, Cheng Yan, Hualan Chen   +4 more
semanticscholar   +1 more source

Robust antiviral activity of commonly prescribed antidepressants against emerging coronaviruses: in vitro and in silico drug repurposing studies

Scientific Reports, 2022
During the current coronavirus disease 2019 (COVID-19) pandemic, symptoms of depression are commonly documented among both symptomatic and asymptomatic quarantined COVID-19 patients.
Omnia Kutkat, Yassmin Moatasim, Ahmed A. Al‐Karmalawy, Hamada S. Abulkhair, Mokhtar R. Gomaa, Ahmed N. El-Taweel, Noura M. Abo Shama, Mohamed GabAllah, Dina B. Mahmoud, Ghazi Kayali, Mohamed A. Ali, Ahmed Kandeil, Ahmed Mostafa   +12 more
doaj   +1 more source

Design and Immunological Properties of the Novel Subunit Virus-like Vaccine against SARS-CoV-2

Vaccines, 2022
The COVID-19 pandemic is ongoing, and the need for safe and effective vaccines to prevent infection and to control spread of the virus remains urgent. Here, we report the development of a SARS-CoV-2 subunit vaccine candidate (Betuvax-CoV-2) based on RBD ...
Igor V. Krasilnikov, Aleksandr V. Kudriavtsev, Anna V. Vakhrusheva, Maria E. Frolova, Aleksandr V. Ivanov, Marina A. Stukova, Ekaterina A. Romanovskaya-Romanko, Kirill A. Vasilyev, Nataliya V. Mushenkova, Artur A. Isaev   +9 more
doaj   +1 more source

Nanomolecular detection of human influenza virus type A using reverse transcription loop-mediated isothermal amplification assisted with rod-shaped gold nanoparticles [PDF]

, 2014
Reverse transcription loop-mediated isothermal amplification (RT-LAMP) and rod-shaped gold nanoparticles (gold nanorods; GNRs) were employed for nanomolecular detection of human influenza virus type A RNA.
Gill, P., Niazi, A., Nikbakht, H., Tabarraei, A.   +3 more
core   +1 more source

TMPRSS2 Is the Major Activating Protease of Influenza A Virus in Primary Human Airway Cells and Influenza B Virus in Human Type II Pneumocytes

Journal of Virology, 2019
Influenza A viruses (IAV) and influenza B viruses (IBV) cause significant morbidity and mortality during seasonal outbreaks. Cleavage of the viral surface glycoprotein hemagglutinin (HA) by host proteases is a prerequisite for membrane fusion and ...
H. Limburg, Anne Harbig, Dorothea Bestle, D. A. Stein, H. Moulton, J. Jaeger, Harshavardhan Janga, Kornelia Hardes, J. Koepke, Leon N. Schulte, A. Koczulla, B. Schmeck, H. Klenk, E. Böttcher-Friebertshäuser   +13 more
semanticscholar   +1 more source

Avian Influenza A (H5N1) Infection in Humans [PDF]

New England Journal of Medicine, 2005
published_or_final_version
Beigel, JH, Yuen, KY, Touch, S, Nicoll, A, Hien, TT, Hien, NT, Tien, NTK, Lochindarat, S, De Jong, MD, Hyer, R, Hayden, FG, Han, AM, Farrar, J   +12 more
openaire   +6 more sources

Avian Influenza Virus Infections in Humans [PDF]

Chest, 2006
Seroepidemiologic and virologic studies since 1889 suggested that human influenza pandemics were caused by H1, H2, and H3 subtypes of influenza A viruses. If not for the 1997 avian A/H5N1 outbreak in Hong Kong of China, subtype H2 is the likely candidate for the next pandemic.
Wong, SSY, Yuen, KY
openaire   +5 more sources

Global Distribution and Molecular Evolution of Bat Coronaviruses

Zoonotic Diseases
Bat coronaviruses cause a wide range of illnesses in humans and animals. Bats are known to harbor a wide diversity of Alphacoronaviruses and Betacoronaviruses.
Mohamed El Sayes, Rebecca Badra, Mohamed A. Ali, Rabeh El-Shesheny, Ghazi Kayali   +4 more
doaj   +1 more source

Viruses associated with pneumonia in adults. [PDF]

, 2012
Viral pneumonia, which is typically associated with disease in childhood, is increasingly recognized as causing problems in adults. Certain viruses, such as influenza virus, can attack fully immunocompetent adults, but many viruses take advantage of more-
Cesario, Thomas C
core   +1 more source

Deep mutational scanning of hemagglutinin helps predict evolutionary fates of human H3N2 influenza variants

Proceedings of the National Academy of Sciences of the United States of America, 2018
Significance A key goal in the study of influenza virus evolution is to forecast which viral strains will persist and which ones will die out. Here we experimentally measure the effects of all amino acid mutations to the hemagglutinin protein from a ...
Juhye M. Lee, J. Huddleston, Michael B. Doud, K. Hooper, N. Wu, T. Bedford, J. Bloom   +6 more
semanticscholar   +1 more source