Results 41 to 50 of about 27,895 (134)

Recurring Temporal Association Between Influenza A Epidemics and Subsequent Influenza B Dominance in Post‐Pandemic Korea, 2022−2026

Journal of Medical Virology, Volume 98, Issue 10, October 2026.
ABSTRACT Post‐pandemic influenza dynamics have shown unusual patterns globally. We investigated the re‐emergence and recurrent seasonal dominance of influenza B in Korea across three post‐pandemic seasons (2022−2026). We analyzed 157 consecutive weeks of national sentinel surveillance data (K‐SenS, Korea Disease Control and Prevention Agency), covering
Yoon Lee, Yoonsun Yoon, Ji Eun Park, Won Keun Kim, Youn Young Choi, Yun‐Kyung Kim, Changmin Kang, Young Yoo, Young June Choe   +8 more
wiley   +1 more source

Interim estimates of divergence date and vaccine strain match of human influenza A(H3N2) virus from systematic influenza surveillance (2010–2015) in Hangzhou, southeast of China

International Journal of Infectious Diseases, 2015
Objectives: In the post-pandemic period 2010–2015, seasonal influenza A(H3N2) virus predominated in Hangzhou, southeast of China, with an increased activity and semi-annual seasons.
Jun Li, Yin-yan Zhou, Yu Kou, Xin-fen Yu, Zhi-bei Zheng, Xu-hui Yang, Hao-qiu Wang   +6 more
doaj   +1 more source

Anti‐idiotypic antibodies as molecular mimics of conserved influenza hemagglutinin epitopes

Protein Science, Volume 35, Issue 10, October 2026.
Abstract Broadly neutralizing antibodies (bNAbs) provide insights for developing universal influenza vaccines through their ability to neutralize diverse viral strains. However, designing antigens that reliably elicit bNAb responses remains challenging due to the difficulty in targeting conserved epitopes with a single antigen.
Hiroshi Itou, Kaori Sano, Akira Ainai, Kazushige Otsuki, Toshikazu Inoue, Takuya Hemmi, Hideki Hasegawa, Tadaki Suzuki   +7 more
wiley   +1 more source

Membrane‐Permeable Nucleoside T‐1106 Diphosphate and Triphosphate Analogues as Antiviral Pronucleotides

Chemistry – A European Journal, Volume 32, Issue 34, 11 September 2026.
Favipiravir (T‐705) and the non‐fluorinated counterpart (T‐1106) are antiviral agents that inhibit the RNA‐dependent RNA polymerase (RdRp) of various RNA viruses. The antiviral efficacy of nucleoside analogues is strongly dependent on their intracellular activation by cellular kinases to produce their corresponding triphosphate metabolites (T‐705‐RTP ...
Chris Meier, Duan Li, Leentje Persoons, Graciela Andrei, Robert Snoeck, Dominique Schols, Lieve Naesens, Xiao Jia   +7 more
wiley   +1 more source

H3N2 avian influenza viruses detected in live poultry markets in China bind to human-type receptors and transmit in guinea pigs and ferrets

Emerging Microbes and Infections, 2019
The H3N2 influenza viruses became widespread in humans during the 1968 H3N2 pandemic and have been a major cause of influenza epidemics ever since. Different lineages of H3N2 influenza viruses are also commonly found in animals. If a different lineage of
Lizheng Guan, Jianzhong Shi, Xingtian Kong, Shujie Ma, Yaping Zhang, Xin Yin, Xijun He, Liling Liu, Yasuo Suzuki, Chengjun Li, Guohua Deng, Hualan Chen   +11 more
doaj   +1 more source

Engineering Antibodies into Targeted Chimeras: From Recognition Modules to Programmable Degraders

Advanced Science, Volume 13, Issue 50, 7 September 2026.
Antibody can be engineered into diverse lysosome‐targeting chimeras that convert target recognition into active degradation. By coupling antibody binding with recruited receptors, encoded domains, conjugated ligands, or nanoparticle scaffolds, these antibody‐associated targeted chimeras (AbTACs) platforms direct extracellular and membrane proteins ...
Kaige Chen, Quanyin Hu
wiley   +1 more source

Genetic characterization of an H3N2 canine influenza virus strain in China in 2023—acquisition of novel human-like amino acid substitutions

Frontiers in Veterinary Science
Around 2005, influenza A virus (IAV) once again crossed species barriers and established a stable lineage within canine populations. Currently, avian-origin H3N2 canine influenza virus (CIV) is the only strain of influenza that is stably circulating in ...
Sihan Li, Liangyu Chu, Yancheng Zhang, Yaxuan Yu, Guoqing Wang   +4 more
doaj   +1 more source

Genetic and antigenic divergence in the influenza A(H3N2) virus circulating between 2016 and 2017 in Thailand.

PLoS ONE, 2017
Influenza virus evolves rapidly due to the accumulated genetic variations on the viral sequence. Unlike in North America and Europe, influenza season in the tropical Southeast Asia spans both the rainy and cool seasons.
Nungruthai Suntronwong, Sirapa Klinfueng, Preeyaporn Vichiwattana, Sumeth Korkong, Thanunrat Thongmee, Sompong Vongpunsawad, Yong Poovorawan   +6 more
doaj   +1 more source

Severity of heterosubtypic influenza virus infection in ferrets is reduced by live attenuated influenza vaccine

npj Vaccines, 2021
Live attenuated influenza vaccine (LAIV) is widely used to protect humans from seasonal influenza infection, particularly in children. In contrast to inactivated vaccines, the LAIV can induce both mucosal and cellular immune responses.
Anthony C. Marriott, Karen E. Gooch, Phillip J. Brown, Kathryn A. Ryan, Nicola J. Jones, Natasha Merredew, Nathan Wiblin, Oliver Dibben, Helen Bright, Bassam Hallis, Catherine J. Whittaker, Miles W. Carroll   +11 more
doaj   +1 more source

Some Exposure for Influenza Hemagglutinin Interface Antibodies

Immunological Reviews, Volume 342, Issue 1, September 2026.
ABSTRACT Influenza viruses are a constant threat to human health. Current vaccines often confer low to moderate protection against infection with seasonal viruses and little‐to‐no protection against pandemic viruses. Improved vaccines are needed. These vaccines will need to reliably elicit antibodies to conserved sites that are broadly protective.
Kevin R. McCarthy
wiley   +1 more source