Results 21 to 30 of about 118,844,745 (215)

Influenza virus A infection of human monocyte and macrophage subpopulations reveals increased susceptibility associated with cell differentiation [PDF]

, 2012
Influenza virus infection accounts for significant morbidity and mortality world-wide. Interactions of the virus with host cells, particularly those of the macrophage lineage, are thought to contribute to various pathological changes associated with poor
Jackson David, Richard E. Randall, Richard E. Randall (190211), Nash, A.A., Anthony A Nash, Hoeve, M.A., Marieke A Hoeve, Anthony A. Nash, Hoeve Marieke A., Nash, Anthony A., Dransfield, I., Marieke A. Hoeve (190207), David Jackson (84936), Richard E Randall, Randall Richard E., Jackson, David, Randall, R.E., Nash Anthony A., David Jackson, Jackson, D., Ian Dransfield (190213), Dransfield, Ian, Marieke A. Hoeve, Anthony A. Nash (190209), Randall, Richard E., Ian Dransfield, Hoeve, Marieke A., Dransfield Ian, Randall, Richard E.; id_orcid   +28 more
core   +1 more source

Highly Cross-Reactive and Protective Influenza A Virus H3N2 Hemagglutinin- and Neuraminidase-Specific Human Monoclonal Antibodies

Microbiology Spectrum, 2023
Due to antigenic drift and shift of influenza A viruses (IAV) and the tendency to elicit predominantly strain-specific antibodies, humanity remains susceptible to new strains of seasonal IAV and is at risk from viruses with pandemic potential for which ...
Michael Piepenbrink, Fatai Oladunni, Aitor Nogales, Ahmed M. Khalil, Theresa Fitzgerald, Madhubanti Basu, Christopher Fucile, David J. Topham, Alexander F. Rosenberg, Luis Martinez-Sobrido, James J. Kobie   +10 more
doaj   +1 more source

Origins and Evolutionary Dynamics of H3N2 Canine Influenza Virus [PDF]

Journal of Virology, 2015
ABSTRACT Influenza A viruses (IAVs) are maintained mainly in wild birds, and despite frequent spillover infections of avian IAVs into mammals, only a small number of viruses have become established in mammalian hosts. A new H3N2 canine influenza virus (CIV) of avian origin emerged in Asia in the mid-2000s and is now circulating in dog ...
Henan, Zhu, Joseph, Hughes, Pablo R, Murcia   +2 more
openaire   +2 more sources

Estimating reassortment rates in co-circulating Eurasian swine influenza viruses [PDF]

, 2012
Swine have often been considered as a mixing vessel for different influenza strains. In order to assess their role in more detail, we undertook a retrospective sequencing study to detect and characterize the reassortants present in European swine and to ...
Pybus, OG, McCauley, J. W., Brown, I. H., Kellam, P., Lycett, S., Baillie, G., Baillie, G, Coulter, E, Brown, IH, Lycett, S. J., Lycett, SJ, Coulter, E., McCauley, JW, Leigh Brown, A., Wood, J. L. N., Pybus, Oliver G., Bhatt, S., Kellam, P, N Wood, J., ?, ?, Wood, JLN, Bhatt, S, Brown, AJ Leigh, Brown, A. J. Leigh, Pybus, O. G., Brown, I., McCauley, J.   +26 more
core   +1 more source

Emergence and Evolution of Novel Canine-Avian Reassortant H3N2 Influenza A Viruses in Duck in Leizhou Peninsula, China

Frontiers in Microbiology, 2022
Avian-to-mammal transmission and mammalian adaptation of avian influenza virus (AIV) are threats to public health and of great concern. The H3 subtype of influenza virus has low pathogenicity and is widely distributed in humans, canines, equines and ...
Qiucheng Yao, Wenhong Mai, Yuexiao Lian, Mengdi Zhang, Qiang Yao, Caiyun Huang, Ye Ge, Zhihui Zhao   +7 more
doaj   +1 more source

Recurring Temporal Association Between Influenza A Epidemics and Subsequent Influenza B Dominance in Post-Pandemic Korea, 2022-2026. [PDF]

J Med Virol
ABSTRACT Post‐pandemic influenza dynamics have shown unusual patterns globally. We investigated the re‐emergence and recurrent seasonal dominance of influenza B in Korea across three post‐pandemic seasons (2022−2026). We analyzed 157 consecutive weeks of national sentinel surveillance data (K‐SenS, Korea Disease Control and Prevention Agency), covering
Lee Y, Yoon Y, Park JE, Kim WK, Choi YY, Kim YK, Kang C, Yoo Y, Choe YJ.   +8 more
europepmc   +2 more sources

An epitope-optimized human H3N2 influenza vaccine induces broadly protective immunity in mice and ferrets

npj Vaccines, 2022
There is a crucial need for an improved H3N2 influenza virus vaccine due to low vaccine efficacy rates and increased morbidity and mortality associated with H3N2-dominated influenza seasons.
Brianna L. Bullard, Jennifer DeBeauchamp, Matthew J. Pekarek, Erika Petro-Turnquist, Peter Vogel, Richard J. Webby, Eric A. Weaver   +6 more
doaj   +1 more source

Pre-existing heterosubtypic immunity provides a barrier to airborne transmission of influenza viruses.

PLoS Pathogens, 2021
Human-to-human transmission of influenza viruses is a serious public health threat, yet the precise role of immunity from previous infections on the susceptibility to airborne infection is still unknown.
Valerie Le Sage, Jennifer E Jones, Karen A Kormuth, William J Fitzsimmons, Eric Nturibi, Gabriella H Padovani, Claudia P Arevalo, Andrea J French, Annika J Avery, Richard Manivanh, Elizabeth E McGrady, Amar R Bhagwat, Adam S Lauring, Scott E Hensley, Seema S Lakdawala   +14 more
doaj   +1 more source

Cloned defective interfering influenza virus protects ferrets from pandemic 2009 influenza A virus and allows protective immunity to be established [PDF]

, 2012
Influenza A viruses are a major cause of morbidity and mortality in the human population, causing epidemics in the winter, and occasional worldwide pandemics.
Cheung, Linda, Dimmock Nigel J., Dove, Brian K., Scott, P. D. (Paul D.), Carroll, Miles W., Linda Cheung, Miles W Carroll, Brian K Dove, Dove Brian K., Taylor Irene, Bassam Hallis, Meng, Bo, Easton, A. J. (Andrew J.), Marriott, Anthony C., Hallis, Bassam, Miles W. Carroll (111071), Dimmock, N. J., Linda Cheung (71020), Andrew J. Easton (111072), Irene Taylor (111066), Scott Paul D., Bo Meng (111065), Hallis Bassam, Taylor, Irene, Andrew J Easton, Paul D Scott, Bo Meng, Brian K. Dove (111063), Meng Bo, Paul D. Scott (111064), Nigel J Dimmock, Marriott Anthony C., Irene Taylor, Anthony C Marriott, Nigel J. Dimmock (111061), Carroll Miles W., Cheung Linda, Bassam Hallis (111069), Easton Andrew J., Anthony C. Marriott (111070)   +39 more
core   +2 more sources

Host-Adaptive Signatures of H3N2 Influenza Virus in Canine

Frontiers in Veterinary Science, 2021
Wild aquatic birds are the primary natural reservoir of influenza A viruses (IAVs), although a small number of viruses can spill over to mammals and circulate. The focus of IAV infection in mammals was largely limited to humans and swine variants, until the emergence of H3N2 canine influenza viruses (CIVs), which provides new perspective for ...
Tongwen Xu, Jia Liu, Zengzhao Qiu, Qijun Liao, Yuan Peng, Yongkun Chen, Yuelong Shu   +6 more
openaire   +3 more sources