Results 11 to 20 of about 27,895 (134)

Predominance of a Drifted Influenza A (H3N2) Clade and its Association with Age-specific Influenza Vaccine Effectiveness Variations, Influenza Season 2018–2019

Vaccines, 2020
Background: Influenza A (H3N2) clade 3C.3a was the predominant influenza virus in Israel throughout the 2018-2019 season, constituting a drift from the influenza A (H3N2) vaccine.
Aharona Glatman-Freedman, Rakefet Pando, Hanna Sefty, Itay Omer, Alina Rosenberg, Yaron Drori, Ital Nemet, Ella Mendelson, Lital Keinan-Boker, Michal Mandelboim, for the Israeli Influenza Surveillance Network (IISN)   +10 more
doaj   +1 more source

Diversity in the Circulation of Influenza A(H3N2) Viruses in the Northern Hemisphere in the 2018–19 Season

Vaccines, 2021
While vaccination is considered the most effective means to prevent influenza infection, its seasonal effectiveness varies, depending on the circulating influenza strains.
Rakefet Pando, Shahar Stern, Ital Nemet, Aharona Glatman-Freedman, Hanna Sefty, Neta S. Zuckerman, Yaron Drori, Nehemya Friedman, John W. McCauley, Lital Keinan-Boker, Ella Mendelson, Rodney S. Daniels, Michal Mandelboim   +12 more
doaj   +1 more source

Transmission of Avian Influenza Virus (H3N2) to Dogs

Emerging Infectious Diseases, 2008
In South Korea, where avian influenza virus subtypes H3N2, H5N1, H6N1, and H9N2 circulate or have been detected, 3 genetically similar canine influenza virus (H3N2) strains of avian origin (A/canine/Korea/01/2007, A/canine/Korea/02/2007, and A/canine ...
Daesub Song, Bokyu Kang, Chulseung Lee, Linda J. Saif, Gunwoo Ha, Dongseok Kang, Seongjun Park, Bongkyun Park, Jinsik Oh   +8 more
doaj   +1 more source

Highly Cross-Reactive and Protective Influenza A Virus H3N2 Hemagglutinin- and Neuraminidase-Specific Human Monoclonal Antibodies

Microbiology Spectrum, 2023
Due to antigenic drift and shift of influenza A viruses (IAV) and the tendency to elicit predominantly strain-specific antibodies, humanity remains susceptible to new strains of seasonal IAV and is at risk from viruses with pandemic potential for which ...
Michael Piepenbrink, Fatai Oladunni, Aitor Nogales, Ahmed M. Khalil, Theresa Fitzgerald, Madhubanti Basu, Christopher Fucile, David J. Topham, Alexander F. Rosenberg, Luis Martinez-Sobrido, James J. Kobie   +10 more
doaj   +1 more source

Emergence and Evolution of Novel Canine-Avian Reassortant H3N2 Influenza A Viruses in Duck in Leizhou Peninsula, China

Frontiers in Microbiology, 2022
Avian-to-mammal transmission and mammalian adaptation of avian influenza virus (AIV) are threats to public health and of great concern. The H3 subtype of influenza virus has low pathogenicity and is widely distributed in humans, canines, equines and ...
Qiucheng Yao, Wenhong Mai, Yuexiao Lian, Mengdi Zhang, Qiang Yao, Caiyun Huang, Ye Ge, Zhihui Zhao   +7 more
doaj   +1 more source

Human Infections with Novel Reassortant Influenza A(H3N2)v Viruses, United States, 2011

Emerging Infectious Diseases, 2012
During July–December 2011, a variant virus, influenza A(H3N2)v, caused 12 human cases of influenza. The virus contained genes originating from swine, avian, and human viruses, including the M gene from influenza A(H1N1)pdm09 virus.
Stephen Lindstrom, Rebecca Garten, Amanda Balish, Bo Shu, Shannon Emery, LaShondra Berman, Nathelia Barnes, Katrina Sleeman, Larisa Gubareva, Julie Villanueva, Alexander Klimov   +10 more
doaj   +1 more source

An epitope-optimized human H3N2 influenza vaccine induces broadly protective immunity in mice and ferrets

npj Vaccines, 2022
There is a crucial need for an improved H3N2 influenza virus vaccine due to low vaccine efficacy rates and increased morbidity and mortality associated with H3N2-dominated influenza seasons.
Brianna L. Bullard, Jennifer DeBeauchamp, Matthew J. Pekarek, Erika Petro-Turnquist, Peter Vogel, Richard J. Webby, Eric A. Weaver   +6 more
doaj   +1 more source

Pre-existing heterosubtypic immunity provides a barrier to airborne transmission of influenza viruses.

PLoS Pathogens, 2021
Human-to-human transmission of influenza viruses is a serious public health threat, yet the precise role of immunity from previous infections on the susceptibility to airborne infection is still unknown.
Valerie Le Sage, Jennifer E Jones, Karen A Kormuth, William J Fitzsimmons, Eric Nturibi, Gabriella H Padovani, Claudia P Arevalo, Andrea J French, Annika J Avery, Richard Manivanh, Elizabeth E McGrady, Amar R Bhagwat, Adam S Lauring, Scott E Hensley, Seema S Lakdawala   +14 more
doaj   +1 more source

ANTIVIRAL EFFECT OF «KAGOCEL» SUBSTANCE IN VITRO ON INFLUENZA VIRUSES H1N1, H1N1PDM09 AND H3N2

Вопросы вирусологии, 2019
Introduction. Active circulation of pandemic influenza and new variants of influenza H3N2 strains requires monitoring of antiviral efficacy of drugs permitted for influenza therapy in the Russian Federation. Purpose.
I. T. Fediakina, M. V. Konopleva, E. S. Proshina, E. V. Linnik, N. I. Nikitina   +4 more
doaj   +1 more source

Avian Influenza Virus PB1 Gene in H3N2 Viruses Evolved in Humans To Reduce Interferon Inhibition by Skewing Codon Usage toward Interferon-Altered tRNA Pools

mBio, 2018
Influenza A viruses cause an annual contagious respiratory disease in humans and are responsible for periodic high-mortality human pandemics. Pandemic influenza A viruses usually result from the reassortment of gene segments between human and avian ...
Bartram L. Smith, Guifang Chen, Claus O. Wilke, Robert M. Krug   +3 more
doaj   +1 more source