Influenza Vaccine Effectiveness Against Mild and Severe Outcomes: A Comparison Study in Portugal. [PDF]
Influenza Other Respir VirusesABSTRACT Background Influenza vaccination is an effective public health intervention to lessen influenza effect on healthcare and has been recommended to prevent severe outcomes. Previous studies present higher influenza vaccine effectiveness (IVE) estimates against primary care medically attended (outpatients) compared to hospitalised cases ...
Mourao F +5 more
europepmc +2 more sources
Clinical Course, Viral Load, and (Sub)Type of Influenza in Hospitalized Children in Southern Germany. [PDF]
J Med VirolABSTRACT This study aimed to assess the relationship between clinical course and influenza virus characteristics by quantifying viral load and performing phylogenetic analyses in hospitalized children. Children aged 0–3 years presenting with an acute respiratory tract infection (RTI) at the Childrens' Hospital Heidelberg/Germany were included and ...
Klemm S +9 more
europepmc +2 more sources
Epidemiological, Clinical and Viral Genomic Features of Influenza Virus Infections Among Pilgrims During the Grand Magal of Touba Over 7 Years (2018-2024). [PDF]
J Med VirolABSTRACT Large international gatherings such as the Grand Magal of Touba in Senegal may favor influenza A/B virus (IABV) transmission. We analyzed IABV genomes from human samples collected during the event in 2018–2024. Next‐generation sequencing was performed for 190 qPCR‐positive nasopharyngeal samples.
Diouf C +13 more
europepmc +2 more sources
Pulmonary Function and Clinical Manifestations of Patients Infected with Mild Influenza A Virus Subtype H1N1: A One-Year Follow-Up [PDF]
PLoS ONE, 2015 To investigate the long-term effects of mild H1N1 influenza infection on the pulmonary function of a cohort of patients.Forty-eight patients, all diagnosed with influenza A virus subtype H1N1 in 2009, were retrospectively included in this study.
Liping Peng, Shucheng Hua
exaly +2 more sources
Influenza Vaccination Effectiveness in Preventing Hospitalization of Adults With Underlying Medical Conditions: A Multicentre Case-Control Study. [PDF]
Influenza Other Respir VirusesABSTRACT Background Seasonal influenza, especially in persons with underlying medical conditions, is a substantial global burden. Influenza vaccination effectiveness (VE) varies annually, requiring continuous evaluation due to evolving viruses and vaccination coverages. Our aim was to investigate influenza VE in preventing hospitalization for confirmed
Toledo D +12 more
europepmc +2 more sources
Antiviral Resistance Associated With Multiple Mutations Occurring in Seasonal Influenza A(H3N2) Virus in a Patient Treated With Oseltamivir. [PDF]
Clin Case RepABSTRACT Our case highlights the importance of early diagnosis in respiratory illness and timely detection of drug resistance so that antiviral treatment can be initiated and modified, particularly for high‐risk groups. Vaccination and early, carefully dosed antiviral treatment are key to mitigating severe influenza cases, especially in ...
Hussain S +9 more
europepmc +2 more sources
Multiple reassortment events in the evolutionary history of H1N1 influenza A virus since 1918. [PDF]
PLoS Pathogens, 2008 The H1N1 subtype of influenza A virus has caused substantial morbidity and mortality in humans, first documented in the global pandemic of 1918 and continuing to the present day.
Martha I Nelson +11 more
doaj +1 more source
Catastrophic antiphospholipid syndrome (CAPS) induced by influenza A virus subtype H1N1 [PDF]
BMJ Case Reports, 2013 Catastrophic antiphospholipid syndrome (CAPS) has been associated with several bacterial and viral infections. We presented a case report of a woman who presented to the emergency room, with influenza A virus subtype H1N1 which progressed to CAPS in the course of 17 days. We believe this is the first case that links CAPS with H1N1.
Melonie L, Durkin +3 more
openaire +2 more sources
Detection in 2009 of the Swine Origin Influenza A (H1N1) Virus by a Subtyping Microarray [PDF]
Journal of Clinical Microbiology, 2009 A novel H1N1 swine origin influenza A (IAV) virus (S-OIV) was discovered in specimens from two unrelated children in the San Diego area in mid-April 2009 (1, 2). Those samples were positive for IAV but negative for both human H1 and H3 subtypes. The outbreak evolved rapidly, and the World Health Organization (WHO) declared the highest phase 6 worldwide
Qing, Lu +5 more
openaire +2 more sources
Epidemiological and Virological Characterization of 2009 Pandemic Influenza A Virus Subtype H1N1 in Madagascar [PDF]
The Journal of Infectious Diseases, 2012 Madagascar was one of the first African countries to be affected by the 2009 pandemic of influenza A virus subtype H1N1 [A(H1N1)pdm2009] infection. The outbreak started in the capital city, Antananarivo, and then spread throughout the country from October 2009 through February 2010.Specimens from patients presenting with influenza-like illness were ...
Arnaud, Orelle +8 more
openaire +2 more sources