Results 21 to 30 of about 50,202 (247)

In silico modification of oseltamivir as neuraminidase inhibitor of influenza A virus subtype H1N1 [PDF]

The Journal of Biomedical Research, 2015
This research focused on the modification of the functional groups of oseltamivir as neuraminidase inhibitor against influenza A virus subtype H1N1. Interactions of three of the best ligands were evaluated in the hydrated state using molecular dynamics simulation at two different temperatures. The docking result showed that AD3BF2D ligand (N-[(1S,6R)-5-
Tambunan, Usman Sumo Friend, Rachmania, Rizky Archintya, Parikesit, Arli Aditya   +2 more
openaire   +2 more sources

Epidemiological and Virological Characterization of 2009 Pandemic Influenza A Virus Subtype H1N1 in Madagascar [PDF]

The Journal of Infectious Diseases, 2012
Madagascar was one of the first African countries to be affected by the 2009 pandemic of influenza A virus subtype H1N1 [A(H1N1)pdm2009] infection. The outbreak started in the capital city, Antananarivo, and then spread throughout the country from October 2009 through February 2010.Specimens from patients presenting with influenza-like illness were ...
Arnaud, Orelle, Norosoa Harline, Razanajatovo, Soatiana, Rajatonirina, Jonathan, Hoffmann, Laurence, Randrianasolo, Girard Marcellin, Razafitrimo, Dhamari, Naidoo, Vincent, Richard, Jean-Michel, Heraud   +8 more
openaire   +2 more sources

Detection in 2009 of the Swine Origin Influenza A (H1N1) Virus by a Subtyping Microarray [PDF]

Journal of Clinical Microbiology, 2009
A novel H1N1 swine origin influenza A (IAV) virus (S-OIV) was discovered in specimens from two unrelated children in the San Diego area in mid-April 2009 (1, 2). Those samples were positive for IAV but negative for both human H1 and H3 subtypes. The outbreak evolved rapidly, and the World Health Organization (WHO) declared the highest phase 6 worldwide
Qing, Lu, Xing-Quan, Zhang, Sergei L Kosakovsky, Pond, Sharon, Reed, Robert T, Schooley, Yu-Tsueng, Liu   +5 more
openaire   +2 more sources

Moderate Vaccine Effectiveness against Severe Acute Respiratory Infection Caused by A(H1N1)pdm09 Influenza Virus and No Effectiveness against A(H3N2) Influenza Virus in the 2018/2019 Season in Italy

Vaccines, 2020
Every season, circulating influenza viruses change; therefore, vaccines must be reformulated each year. We aimed to estimate vaccine effectiveness (VE) against severe influenza infection for the 2018/19 season in Italy.
Caterina Rizzo, Francesco Gesualdo, Daniela Loconsole, Elisabetta Pandolfi, Antonino Bella, Andrea Orsi, Giulia Guarona, Donatella Panatto, Giancarlo Icardi, Christian Napoli, Giovanni Battista Orsi, Ilaria Manini, Emanuele Montomoli, Ilaria Campagna, Luisa Russo, Valeria Alfonsi, Simona Puzelli, Antonino Reale, Umberto Raucci, Livia Piccioni, Carlo Concato, Marta Luisa Ciofi Degli Atti, Alberto Villani, Maria Chironna, Alberto Eugenio Tozzi   +24 more
doaj   +1 more source

Rapid Semiautomated Subtyping of Influenza Virus Species during the 2009 Swine Origin Influenza A H1N1 Virus Epidemic in Milwaukee, Wisconsin [PDF]

Journal of Clinical Microbiology, 2009
ABSTRACT In the spring of 2009, a novel influenza A (H1N1) virus (swine origin influenza virus [S-OIV]) emerged and began causing a large outbreak of illness in Milwaukee, WI. Our group at the Midwest Respiratory Virus Program laboratory developed a semiautomated real-time multiplex reverse transcription-PCR assay (Seasonal), employing the ...
Michael E, Bose, Eric T, Beck, Nate, Ledeboer, Sue C, Kehl, Lisa A, Jurgens, Teresa, Patitucci, Lorraine, Witt, Elizabeth, LaGue, Patrick, Darga, Jie, He, Jiang, Fan, Swati, Kumar, Kelly J, Henrickson   +12 more
openaire   +2 more sources

Development of DNA-Biochip for Identification of Influenza A Virus Subtypes

Проблемы особо опасных инфекций, 2012
Developed was the DNA-biochip to identify subtypes of influenza A virus, pathogenic for humans. Microchip was capable of detecting H1, H3, H5-subtypes of hemagglutinin (including H1-subtype of pandemic A/H1N1(2009) influenza virus ) and neuraminidase ...
A. N. Shikov, E. I. Sergeeva, O. K. Demina, V. A. Ternovoy, V. V. Ryabinin, E. V. Kostina, E. M. Malkova, A. N. Sinyakov, A. P. Agaphonov   +8 more
doaj   +1 more source

Illness Severity in Hospitalized Influenza Patients by Virus Type and Subtype, Spain, 2010–2017

Emerging Infectious Diseases, 2020
We conducted a retrospective cohort study to assess the effect of influenza virus type and subtype on disease severity among hospitalized influenza patients in Spain.
Concepción Delgado-Sanz, Clara Mazagatos-Ateca, Jesús Oliva, Alin Gherasim, Amparo Larrauri   +4 more
doaj   +1 more source

Cross-protection against European swine influenza viruses in the context of infection immunity against the 2009 pandemic H1N1 virus : studies in the pig model of influenza [PDF]

, 2015
Pigs are natural hosts for the same influenza virus subtypes as humans and are a valuable model for cross-protection studies with influenza. In this study, we have used the pig model to examine the extent of virological protection between a) the 2009 ...
A Krumbholz, A Lavenu, AC Lowen, AI Karasin, AR Vleeschauwer De, AS Monto, B Brandenburg, B Manicassamy, B Srivastava, CD O’Donnell, CD O’Donnell, CS Kyriakis, CS Kyriakis, DM Skowronski, ED Kilbourne, G Simon, GA Landolt, GG Brownlee, I Skountzou, IH Brown, JC Kash, JH Kreijtz, JL Schulman, K Hoschler, K Reeth Van, K Reeth Van, K Reeth Van, K Reeth Van, K Tamura, Karl De hert, KL Laurie, Kristien Van Reeth, L Campitelli, M Khatri, M Pensaert, M Retamal, M Strengell, MA Marco De, MI Nelson, MJ Sylte, ML Hillaire, MR Castrucci, MR Castrucci, MR Sandbulte, N Busquets, NM Bouvier, PM Colman, PP Heinen, RA Perera, RA Yetter, RJ Garten, S Liang, SL Epstein, SM Brookes, T Sonoguchi, TM Straight, Y Qiu, Y Qiu, Yu Qiu   +58 more
core   +6 more sources

VIRUS-SPECIFIC HUMORAL IMMUNE RESPONSE ISOTYPIC STRUCTURE IN ADULT PATIENTS HOSPITALIZED WITH INFLUENZA A

Инфекция и иммунитет, 2016
The aim of this investigation was a comparative analysis of isotypic structure of specific antiviral systemic humoral immune response in hospitalized patients with influenza caused by virus A(H3N2) or A(H1N1), including the A(H1N1)pdm09. Paired acute and
V. Z. Krivitskaya, A. A. Vasilieva, E. M. Voytsekhovskaya, E. R. Petrova, M. M. Pisareva, Zh. V. Buzitskaya, E. A. Elpaeva, A. A. Go, L. V. Voloshchuk, N. I. Lvov, T. D. Smirnova, A. A. Sominina   +11 more
doaj   +1 more source

Substitutions near the hemagglutinin receptor-binding site determine the antigenic evolution of influenza A H3N2 viruses in U.S. swine [PDF]

, 2014
Swine influenza A virus is an endemic and economically important pathogen in pigs, with the potential to infect other host species. The hemagglutinin (HA) protein is the primary target of protective immune responses and the major component in swine ...
A. L. Vincent, Anderson, Bao, Bowman, Brown, Centers for Disease Control and Prevention, Core Team R, D. F. Burke, Darriba, De Jong, E. Skepner, Edgar, Feng, Fouchier, Garten, Gauger, Harmon, Hinshaw, Houser, Karasin, Kawaoka, Khurana, Kitikoon, Koel, Lewis, Lindstrom, Lorusso, Loving, Maddison, Miller, Montalvao, Myers, N. S. Lewis, Nelson, Nelson, Nfon, Olsen, P. Kitikoon, Paradis, Pena, Polewicz, PyMOL, Röhm, Salmon, Shinde, Skowronski, Smith, Smith, Stamatakis, T. K. Anderson, Tong, Tong, Vincent, Vincent, Vincent, Vincent, Webby, Webby, Ye   +58 more
core   +2 more sources