Results 81 to 90 of about 48,268 (246)

Moderate influenza vaccine effectiveness against A(H1N1)pdm09 virus, and low effectiveness against A(H3N2) subtype, 2018/19 season in Italy

Expert Review of Vaccines, 2019
Background: Influenza vaccines are updated every year to match the vaccine strains with currently circulating viruses; consequently influenza vaccine effectiveness (IVE) has to be assessed annually.
S. Bellino, A. Bella, S. Puzelli, A. Di Martino, M. Facchini, O. Punzo, P. Pezzotti, M. Castrucci, the InfluNet Study Group   +8 more
semanticscholar   +1 more source

Could Environment Affect the Mutation of H1N1 Influenza Virus?

International Journal of Environmental Research and Public Health, 2020
H1N1 subtype influenza A viruses are the most common type of influenza A virus to infect humans. The two major outbreaks of the virus in 1918 and 2009 had a great impact both on human health and social development.
D. Jiang, Qian Wang, Zhihua Bai, Heyuan Qi, Juncai Ma, Wenjun Liu, Fangyu Ding, Jing Li   +7 more
semanticscholar   +1 more source

Multi-Influenza HA Subtype Protection of Ferrets Vaccinated with an N1 COBRA-Based Neuraminidase

Viruses, 2023
The influenza neuraminidase (NA) is a promising target for next-generation vaccines. Protection induced by vaccination with the computationally optimized broadly reactive NA antigen (N1-I COBRA NA) was characterized in both influenza serologically naive ...
A. L. Skarlupka, Xiaojian Zhang, U. Blas-Machado, Spencer F. Sumner, T. Ross   +4 more
semanticscholar   +1 more source

Bee products as alternatives in the treatment of viral infections

Journal of the Science of Food and Agriculture, EarlyView.
Abstract Medicines used in the treatment of viral infections usually reduce symptoms. There is a need to develop drugs that inhibit the viruses and do not merely relieve the symptoms. Natural bee products possess many pharmacological properties and are widely used in folk medicine. There are many studies on the antibacterial effects of bee products but
Michał Otręba, Łukasz Marek, Jerzy Stojko, Anna Rzepecka‐Stojko   +3 more
wiley   +1 more source

In Vitro and In Vivo Antiviral Activity of Nylidrin by Targeting the Hemagglutinin 2-Mediated Membrane Fusion of Influenza A Virus

Viruses, 2020
Influenza A virus, one of the major human respiratory pathogens, is responsible for annual seasonal endemics and unpredictable periodic pandemics. Despite the clinical availability of vaccines and antivirals, the antigenic diversity and drug resistance ...
Yejin Jang, Jin Soo Shin, Joo-Youn Lee, Heegwon Shin, Sang Jick Kim, Meehyein Kim   +5 more
doaj   +1 more source

Influenza-induced thrombocytopenia is dependent on the subtype and sialoglycan receptor and increases with virus pathogenicity.

Blood Advances, 2020
Thrombocytopenia is a common complication of influenza virus infection, and its severity predicts the clinical outcome of critically ill patients. The underlying cause(s) remain incompletely understood. In this study, in patients with an influenza A/H1N1
A. G. Jansen, Thom Spaan, H. Low, D. D. Iorio, J. Brand, Malte Tieke, A. Barendrecht, K. Rohn, G. V. Amerongen, K. Stittelaar, W. Baumgärtner, A. Osterhaus, T. Kuiken, G. Boons, J. Huskens, M. Boes, C. Maas, E. V. D. Vries, E. V. D. Vries   +18 more
semanticscholar   +1 more source

Heterovariant cross-reactive B-cell responses induced by the 2009 pandemic influenza virus A subtype H1N1 vaccine. [PDF]

The Journal of Infectious Diseases, 2013
The generation of heterovariant immunity is a highly desirable feature of influenza vaccines. The goal of this study was to compare the heterovariant B-cell response induced by the monovalent inactivated 2009 pandemic influenza A virus subtype H1N1 (A[H1N1]pdm09) vaccine with that induced by the 2009 seasonal trivalent influenza vaccine (sTIV ...
Xiao‐Song He, S. Sasaki, J. Baer, S. Khurana, H. Golding, J. Treanor, D. Topham, M. Sangster, Hong Jin, C. Dekker, K. Subbarao, H. Greenberg   +11 more
semanticscholar   +4 more sources

Epidemiological and virological characterization of influenza A virus subtype H1N1 at tertiary-care hospital, Ahmedabad

International Journal of Medical Science and Public Health, 2016
Background: In April 2009, a new strain of influenza virus, A H1N1, started to spread in various parts of the world, and the first case was reported on May 16, 2009.[1] The associated morbidity and mortality have made it a major health burden. In this study, we have investigated samples of patients with suspected influenza-like illnesses (ILIs ...
Lavanya Devi, Vibhuti Patel, Nidhi Barot, Sumeeta Soni, M M Vegad   +4 more
openaire   +2 more sources

Improved Sensitivity of a Commercial Reverse Transcription-PCR Test for Subtyping of the 2009 H1N1 Influenza A Virus [PDF]

Journal of Clinical Microbiology, 2011
Rapid detection of influenza A virus and determination of its subtype are important globally for public health surveillance and locally for the selection of antiviral treatment (1). We have used the ProFlu+ assay to test respiratory samples from children for influenza A virus, influenza B virus, and respiratory syncytial virus (RSV) and the ProFlu ST ...
Sandra Smole, Nima Mosammaparast, Alexander J. McAdam, Richard F. Rossi   +3 more
openaire   +2 more sources

Organoid Models to Study Human Infectious Diseases

Cell Proliferation, EarlyView.
Our manuscript reviews the role of organoids as models for studying human infectious diseases, highlighting their irreplaceable contributions to drug testing and vaccine development for significant infectious diseases including HIV, ZIKV, SARS‐CoV‐2 and MPXV.
Sijing Zhu, Dan Chen, Xinzhi Yang, Liuliu Yang, Yuling Han   +4 more
wiley   +1 more source