Results 81 to 90 of about 31,937 (255)

Strategic Preparedness of Broad‐Spectrum Antivirals for Rapid Response Towards Next Pandemics

Small Science, Volume 6, Issue 1, January 2026.
Nanoengineered broad‐spectrum antivirals (BSAs) represent a transformative approach to pandemic preparedness. Unlike virus‐specific drugs requiring separate development, BSAs act across multiple viral families through nanoengineering strategies that enhance solubility, bioavailability, and host‐targeted activity.
Sanoj Rejinold N, Geun‐woo Jin, Jin‐Ho Choy   +2 more
wiley   +1 more source

Timing of Influenza A(H5N1) in Poultry and Humans and Seasonal Influenza Activity Worldwide, 2004–2013

Emerging Infectious Diseases, 2015
Co-circulation of influenza A(H5N1) and seasonal influenza viruses among humans and animals could lead to co-infections, reassortment, and emergence of novel viruses with pandemic potential. We assessed the timing of subtype H5N1 outbreaks among poultry,
Lizette O. Durand, Patrick Glew, Diane Gross, Matthew R. Kasper, Susan C. Trock, Inkyu K. Kim, Joseph S. Bresee, Ruben O. Donis, Timothy M. Uyeki, Marc-Alain Widdowson, Eduardo Azziz-Baumgartner   +10 more
doaj   +1 more source

Highly pathogenic avian influenza virus H5N1 clade 2.3.4.4b from Peru forms a monophyletic group with Chilean isolates in South America

Scientific Reports
Highly pathogenic avian Influenza virus (HPAIV) has spread in an unprecedented extent globally in recent years. Despite the large reports of cases in Asia, Europe, and North America, little is known about its circulation in South America.
Gina R. Castro-Sanguinetti, Rosa Gonzalez-Veliz, Alonso Callupe-Leyva, A. Apaza-Chiara, Javier Jara, Walter Silva, Eliana Icochea, J. More-Bayona   +7 more
semanticscholar   +1 more source

Pathogenicity of Highly Pathogenic Avian Influenza Virus (H5N1) in Adult Mute Swans

Emerging Infectious Diseases, 2008
Adult, healthy mute swans were experimentally infected with highly pathogenic avian influenza virus A/Cygnus cygnus/Germany/R65/2006 subtype H5N1. Immunologically naive birds died, whereas animals with preexisting, naturally acquired avian influenza ...
Donata Kalthoff, Angele Breithaupt, Jens P. Teifke, Anja Globig, Timm Harder, Thomas C. Mettenleiter, Martin Beer   +6 more
doaj   +1 more source

Phylodynamics of H5N1 Highly Pathogenic Avian Influenza in Europe, 2005-2010: Potential for Molecular Surveillance of New Outbreaks. [PDF]

, 2015
Previous Bayesian phylogeographic studies of H5N1 highly pathogenic avian influenza viruses (HPAIVs) explored the origin and spread of the epidemic from China into Russia, indicating that HPAIV circulated in Russia prior to its detection there in 2005 ...
Alkhamis, Mohammad A, Moore, Brian R, Perez, Andres M   +2 more
core   +2 more sources

Phage‐Mediated Presentation of a Conserved HA2 Epitope From Influenza A Virus Elicits Significant IgY Antibody Responses in Broiler Chickens

Veterinary Medicine and Science, Volume 12, Issue 1, January 2026.
The conserved region of HA2 peptide of Influenza A virus was expressed on the surface of Protein VIII from M13 phage. Immunization of broiler chickens by this hybrid phage showed high levels of antibody responses, highlighting its potential as a promising tool for universal vaccine development against Influenza A virus.
Zinat Lotfi, Mehdi Golchin, Mohammad Ali Shamshirgaran   +2 more
wiley   +1 more source

A replication-deficient H9N2 influenza virus carrying H5 hemagglutinin conferred protection against H9N2 and H5N1 influenza viruses in mice

Frontiers in Microbiology, 2022
H5N1 and H9N2 influenza viruses have been reported to cause human infections and are believed to have pandemic potential. The vaccine is an effective tool to prevent influenza virus infection.
Weigang Ren, Shuli Pei, Wenming Jiang, Meixia Zhao, Le Jiang, Honggang Liu, Yongxiang Yi, Yongxiang Yi, Mizhou Hui, Junwei Li, Junwei Li   +10 more
doaj   +1 more source

Development of ssDNA Aptamers for Diagnosis and Inhibition of the Highly Pathogenic Avian Influenza Virus Subtype H5N1

Biomolecules, 2020
Avian influenza (AI) has severely affected the poultry industry worldwide and has caused the deaths of millions of birds. Highly pathogenic avian influenza virus is characterized by high mortality and the ability to transmit from birds to humans.
Sang-Heon Kim, Jae-Woo Choi, A-Ru Kim, Sang-Choon Lee, M. Yoon   +4 more
semanticscholar   +1 more source

Advances in Microbial Diagnostics: Machine Learning and Nanotechnology for Zoonotic Disease Control

WIREs Nanomedicine and Nanobiotechnology, Volume 18, Issue 1, January/February 2026.
This review highlights how integrating machine learning with nanotechnology enables enhanced diagnostics, personalized treatments, and the prediction of outbreaks for zoonotic diseases, offering a unified framework to advance global health. ABSTRACT Zoonotic diseases pose significant global health threats, with microbial pathogens, including bacteria ...
Narges Lotfalizadeh, Cinzia Santucciu, Valentina Chisu, Helia Sepahvand, Abbas Rahdar, Razieh Behzadmehr, Octavio Luiz Franco, Guettari Moez, Luiz Fernando Romanholo Ferreira   +8 more
wiley   +1 more source

Statins for the prevention of cardiovascular events associated with avian influenza: the COVID-19 pandemic as a reference

Annals of Medicine
There is growing concern that the severe respiratory disease in birds (avian influenza or ‘bird flu’) caused by the H5N1 influenza virus, might potentially spread more widely to humans and cause a pandemic.
Alpo Vuorio, Bruce Budowle, Frederick Raal, Petri T. Kovanen   +3 more
doaj   +1 more source