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Novel Genotype of HA Clade 2.3.4.4b H5N8 Subtype High Pathogenicity Avian Influenza Virus Emerged at a Wintering Site of Migratory Birds in Japan, 2021/22 Winter

open access: yesPathogens
Surveillance of avian influenza virus (AIV) was conducted in the 2021–2022 winter season at a wintering site of migratory Anatidae in Japan. An H5N8 subtype high pathogenicity AIV (HPAIV) with a unique gene constellation and four low pathogenicity AIVs ...
Berihun Dires Mihiretu   +4 more
doaj   +3 more sources

Multivalent Inactivated Vaccine Protects Chickens from Distinct Clades of Highly Pathogenic Avian Influenza Subtypes H5N1 and H5N8 [PDF]

open access: yesVaccines
Background/Objective: Highly pathogenic avian influenza (HPAI) H5 subtype remains a significant menace to both the poultry industry and human public health.
Walid H. Kilany   +6 more
doaj   +2 more sources

A Monoclonal Antibody ELISA-Based Assay for Measuring the Potency of Candidate H5 Clade 2.3.4.4b Pandemic Influenza Vaccines. [PDF]

open access: yesInfluenza Other Respir Viruses
ABSTRACT Background The single radial immunodiffusion (SRID) assay is used to determine the potency of inactivated influenza vaccines. Nevertheless, development of alternative influenza vaccine potency assays with greater sensitivity and less reliance on large quantities of reference reagents is needed.
Odin M, Schmeisser F, Soto J, Weir JP.
europepmc   +2 more sources

The C-terminus of non-structural protein 1 (NS1) in H5N8 clade 2.3.4.4 avian influenza virus affects virus fitness in human cells and virulence in mice

open access: yesEmerging Microbes and Infections, 2021
Avian influenza viruses (AIV) H5N8 clade 2.3.4.4 pose a public health threat but the viral factors relevant for its potential adaptation to mammals are largely unknown.
Claudia Blaurock   +8 more
doaj   +1 more source

Genetic characterization of highly pathogenic avian influenza A (H5N8) virus isolated from domestic geese in Iraq, 2018

open access: yesBMC Veterinary Research, 2021
Background Influenza viruses are a continuous threat to avian and mammalian species, causing epidemics and pandemics. After the circulation of H5N1 in 2006, 2015, and 2016 in Iraq, an H5N8 influenza virus emerged in domestic geese in Sulaymaniyah ...
Nahla Muhammad Saeed   +2 more
doaj   +1 more source

Molecular Epidemiology and Evolutionary Analysis of Avian Influenza A(H5) Viruses Circulating in Egypt, 2019–2021

open access: yesViruses, 2022
The highly pathogenic avian influenza (HPAI) H5N8 virus was first detected in Egypt in late 2016. Since then, the virus has spread rapidly among different poultry sectors, becoming the dominant HPAI H5 subtype reported in Egypt.
Naglaa M. Hagag   +13 more
doaj   +1 more source

Sub-Saharan Africa and Eurasia Ancestry of Reassortant Highly Pathogenic Avian Influenza A(H5N8) Virus, Europe, December 2019

open access: yesEmerging Infectious Diseases, 2020
We report detection of a highly pathogenic avian influenza A(H5N8) clade 2.3.4.4b virus in Europe. This virus was generated by reassortment between H5N8 subtype virus from sub-Saharan Africa and low pathogenicity avian influenza viruses from Eurasia.
Edyta Świętoń   +8 more
doaj   +1 more source

Novel incursion of a highly pathogenic avian influenza subtype H5N8 virus in the Netherlands, October 2020 [PDF]

open access: yes, 2020
Abstract The HPAI H5N8 virus detected in mute swans in the Netherlands in October 2020 shares a common ancestor with clade 2.3.4.4b viruses last detected in Egypt in 2018-2019 and has a similar genetic composition. The virus is not directly related to European H5N8 viruses detected in first half of 2020.
Nancy Beerens   +6 more
openaire   +1 more source

Spatio-temporal patterns of highly pathogenic avian influenza virus subtype H5N8 spread, France, 2016 to 2017 [PDF]

open access: yesEurosurveillance, 2018
Introduction France is one of Europe’s foremost poultry producers and the world’s fifth largest producer of poultry meat. In November 2016, highly pathogenic avian influenza (HPAI) virus subtype H5N8 emerged in poultry in the country.
Guinat, Claire   +8 more
openaire   +8 more sources

First detection of highly pathogenic avian influenza virus in Norway

open access: yesBMC Veterinary Research, 2021
Background Several outbreaks of highly pathogenic avian influenza (HPAI) caused by influenza A virus of subtype H5N8 have been reported in wild birds and poultry in Europe during autumn 2020.
Knut Madslien   +11 more
doaj   +1 more source

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