Results 101 to 110 of about 114,195,449 (202)

The Next Disease X‐ H5N6 Avian Influenza's Evolving Threat to Human Health and Chances of Future Global Outbreak: A Narrative Review

Health Science Reports, Volume 8, Issue 11, November 2025.
ABSTRACT Background and Aims H5N6 avian influenza has been a concern that can initiate the next global pandemic (called Disease X). Most infections have been among those in Asia, especially China, since the 2014 first human case. With a fatality rate of 61%, the virus is very deadly, even though the total number of human cases is relatively low.
Shoubeho Sadique Shandhi, Mosiur Rahman, Mohammad Shahriar, Ramisa Anjum   +3 more
wiley   +1 more source

Cross-reactive mouse monoclonal antibodies raised against the hemagglutinin of A/Shanghai/1/2013 (H7N9) protect against novel H7 virus isolates in the mouse model

Emerging Microbes and Infections, 2018
Influenza viruses remain a major global public health risk. In addition to seasonal influenza viruses, epizootic influenza A H7 subtype viruses of both the Asian and North American lineage are of concern due to their pandemic potential.
Daniel Stadlbauer, Fatima Amanat, Shirin Strohmeier, Raffael Nachbagauer, Florian Krammer   +4 more
doaj   +1 more source

A novel broad-spectrum treatment for respiratory virus infections : influenza-based defective interfering virus provides protection against pneumovirus infection in vivo [PDF]

, 2011
Respiratory viruses represent a major clinical burden. Few vaccines and antivirals are available, and the rapid appearance of resistant viruses is a cause for concern.
Edworthy, Nicole Lynn, Nicole L. Edworthy, Andrew J. Easton, Meng, Bo, Easton, A. J. (Andrew J.), Bo Meng, Scott, P. D. (Paul D.), Marriott, Anthony C., Anthony C. Marriott, Nigel J. Dimmock, Dimmock, N. J., Paul D. Scott   +11 more
core   +1 more source

Bacillus Calmette–Guérin-Induced Trained Immunity Is Not Protective for Experimental Influenza A/Anhui/1/2013 (H7N9) Infection in Mice

Frontiers in Immunology, 2018
Avian influenza A of the subtype H7N9 has been responsible for almost 1,600 confirmed human infections and more than 600 deaths since its first outbreak in 2013.
L. Charlotte J. de Bree, L. Charlotte J. de Bree, L. Charlotte J. de Bree, L. Charlotte J. de Bree, Renoud J. Marijnissen, Junda M. Kel, Sietske K. Rosendahl Huber, Peter Aaby, Christine Stabell Benn, Christine Stabell Benn, Marcel V. W. Wijnands, Dimitri A. Diavatopoulos, Dimitri A. Diavatopoulos, Reinout van Crevel, Reinout van Crevel, Leo A. B. Joosten, Leo A. B. Joosten, Mihai G. Netea, Mihai G. Netea, Mihai G. Netea, John Dulos   +20 more
doaj   +1 more source

Genetic evolution of H7N9 virus in China, 2013 [PDF]

The eight genes of the H7N9 virus are closely related to avian influenza viruses found in domestic ducks, wild birds and domestic poultry in Asia. The virus likely emerged from \ue2\u20ac\u153reassortment,\ue2\u20ac?

core  

Retrospective study of risk factors for mortality in human avian influenza A(H7N9) cases in Zhejiang Province, China, March 2013 to June 2014

International Journal of Infectious Diseases, 2015
Background: The influenza A(H7N9) virus causes a serious disease that threatens human health. Fatalities associated with human infections caused by this virus are of great public health concern; however, the possible risk factors are not yet fully known.
Qing-Lin Cheng, Hua Ding, Zhou Sun, Qing-Jun Kao, Xu-Hui Yang, Ren-Jie Huang, Yuan-Yuan Wen, Jing Wang, Li Xie   +8 more
doaj   +1 more source

Influenza A(H7N9) Pandemic Preparedness: Assessment of the Breadth of Heterologous Antibody Responses to Emerging Viruses from Multiple Pre-Pandemic Vaccines and Population Immunity

, 2022
Influenza A(H7N9) viruses remain as a high pandemic threat. The continued evolution of the A(H7N9) viruses poses major challenges in pandemic preparedness strategies through vaccination.
Yaohui Bai, Ian A. York, Mallett, Corey P., Stevens, James, Davis, C. Todd, York, Ian A., Smith, Gale, Louis Fries, Boutet, Philippe, Weimin Zhong, Jefferson, Stacie, Jacqueline M. Katz, Corey P. Mallett, Wen-pin Tzeng, Levine, Min Z., Katz, Jacqueline M., Friel, Damien, Liu, Feng, Fries, Louis, Wentworth, David E., Min Z. Levine, Crystal Holiday, Tzeng, Wen-pin, Holiday, Crystal, Feng Liu, Zhong, Weimin, F. Liaini Gross, C. Todd Davis, Philippe Boutet, Innis, Bruce L., Tumpey, Terrence, Terrence Tumpey, David E. Wentworth, Bai, Yaohui, Gross, F. Liaini, Bruce L. Innis, Stacie Jefferson, Gale Smith, James Stevens, Damien Friel   +39 more
core   +1 more source

Pathogenesis and transmissibility of highly (H7N1) and low (H7N9) pathogenic avian influenza virus infection in red-legged partridge (Alectoris rufa)

Veterinary Research, 2011
An experimental infection with highly pathogenic avian influenza virus (HPAIV) and low pathogenic avian influenza virus (LPAIV) was carried out in red-legged partridges (Alectoris rufa) in order to study clinical signs, gross and microscopic lesions, and
Bertran Kateri, Pérez-Ramírez Elisa, Busquets Núria, Dolz Roser, Ramis Antonio, Darji Ayub, Abad Francesc, Valle Rosa, Chaves Aida, Vergara-Alert Júlia, Barral Marta, Höfle Ursula, Majó Natàlia   +12 more
doaj   +1 more source

Respiratory and systematic humoral and cellular immune response of pigs to a heterosubtypic influenza A virus infection [PDF]

, 2001
The level of heterosubtypic immunity (Het-I) and the immune mechanisms stimulated by a heterosubtypic influenza virus infection were investigated in pigs. Pigs are natural hosts for influenza virus and, like humans, they host both subtypes H1N1 and H3N2.
Heinen, P.P., de Boer Luijtze, E.A., Boer Luijtze, E.A., de, Bianchi, A.T.J.   +3 more
core  

A Single Immunization with Soluble Recombinant Trimeric Hemagglutinin Protects Chickens against Highly Pathogenic Avian Influenza Virus H5N1 [PDF]

, 2010
Background: The highly pathogenic avian influenza (HPAI) virus H5N1 causes multi-organ disease and death in poultry, resulting in significant economic losses in the poultry industry.
Dep Infectieziekten Immunologie, Robert P de Vries, Vries, R.P., de, Rigter, A., Rottier, P.J.M., Cornelissen, A.H.M., de Vries, R.P., Cornelissen, L.A.H.M., Alan Rigter, Cornelis A M de Haan, Strategic Infection Biology, de Haan, C.A.M., Haan, C.A.M., de, de Boer-Luijtze, E.A., Boer-Luijtze, E.A., de, Lisette A H M Cornelissen, Els A de Boer-Luijtze, Peter J M Rottier   +17 more
core   +3 more sources