Immunopotentiation of Different Adjuvants on Humoral and Cellular Immune Responses Induced by HA1-2 Subunit Vaccines of H7N9 Influenza in Mice. [PDF]
In spring 2013, human infections with a novel avian influenza A (H7N9) virus were reported in China. The number of cases has increased with over 200 mortalities reported to date.
Li Song +5 more
doaj +1 more source
Sex Differences in Lung Immunity
ABSTRACT Biological sex has a significant impact on how the immune system develops and responds to foreign and self‐antigens. Sex differences exist in innate and adaptive immune cells, both at homeostasis and in the context of infection and inflammatory diseases such as asthma, cancer, and autoimmune disorders.
Franz Puttur, Clare M. Lloyd
wiley +1 more source
Influenza virus A infection of human monocyte and macrophage subpopulations reveals increased susceptibility associated with cell differentiation [PDF]
Influenza virus infection accounts for significant morbidity and mortality world-wide. Interactions of the virus with host cells, particularly those of the macrophage lineage, are thought to contribute to various pathological changes associated with poor
Jackson David +27 more
core +1 more source
The conserved region of HA2 peptide of Influenza A virus was expressed on the surface of Protein VIII from M13 phage. Immunization of broiler chickens by this hybrid phage showed high levels of antibody responses, highlighting its potential as a promising tool for universal vaccine development against Influenza A virus.
Zinat Lotfi +2 more
wiley +1 more source
Influenza A H5N1 and H7N9 in China: A spatial risk analysis.
BackgroundZoonotic avian influenza poses a major risk to China, and other parts of the world. H5N1 has remained endemic in China and globally for nearly two decades, and in 2013, a novel zoonotic influenza A subtype H7N9 emerged in China.
Chau Minh Bui +3 more
doaj +1 more source
Advances in Microbial Diagnostics: Machine Learning and Nanotechnology for Zoonotic Disease Control
This review highlights how integrating machine learning with nanotechnology enables enhanced diagnostics, personalized treatments, and the prediction of outbreaks for zoonotic diseases, offering a unified framework to advance global health. ABSTRACT Zoonotic diseases pose significant global health threats, with microbial pathogens, including bacteria ...
Narges Lotfalizadeh +8 more
wiley +1 more source
H5N1 Clade 2.2 Polymorphism Tracing Identifies Influenza Recombination and Potential Vaccine Targets [PDF]
Highly pathogenic Influenza A H5N1 was first identified in Guangdong Province in 1996, followed by human cases in Hong Kong in 1997 1. The number of confirmed human cases now exceeds 300 and the associated Case Fatality Rate exceeds 60% 2.
Nasr M. ElSayed +26 more
core +1 more source
Development and evaluation of a SYBR green-based real time RT-PCR assay for detection of the emerging avian influenza A (H7N9) virus. [PDF]
Most recently a novel avian-origin influenza A (H7N9) virus emerged in China and has been associated with lots of human infection and fatal cases. Genetic analysis of the viral genome revealed that this reassortant virus might be better adapted to humans
Zheng Zhu +7 more
doaj +1 more source
From Hive to Health: Anti‐Influenza Properties of Bee Products
Bee products have been long adapted as a natural remedy since centuries ago and studied for their bioactive properties including antimicrobial, anti‐inflammatory, antioxidant, and anticancer effects. Viral infections, including influenza, remain a significant global public health complication signifying the urgency for the development of alternative ...
Wei Wei Loo +3 more
wiley +1 more source
Low dose influenza virus challenge in the ferret leads to increased virus shedding and greater sensitivity to oseltamivir [PDF]
Ferrets are widely used to study human influenza virus infection. Their airway physiology and cell receptor distribution makes them ideal for the analysis of pathogenesis and virus transmission, and for testing the efficacy of anti-influenza ...
Dove, Brian K. +35 more
core +1 more source

