Results 181 to 190 of about 10,711 (202)

Rare variant MX1 alleles increase human susceptibility to zoonotic H7N9 influenza virus

Science, 2021
Poultry passport to pandemic What conditions are required to nurture the seeds of a pandemic? The avian influenza virus H7N9 rarely spills over into humans, but when it does, mortality exceeds 30%, far in excess of that of severe acute respiratory ...
Yongkun Chen, Laura Graf, Tao Chen, Q. Liao, T. Bai, Philipp P. Petric, Wenfei Zhu, Lei Yang, Jie Dong, Jian Lu, Ying Chen, Juan Shen, O. Haller, P. Staeheli, G. Kochs, Dayan Wang, M. Schwemmle, Y. Shu   +17 more
semanticscholar   +1 more source

Rapid hemagglutinin subtyping of novel avian-origin influenza A(H7N9) virus using a diagnostic microarray

BioChip Journal, 2014
An epidemic of human H7N9 influenza virus infection has recently emerged in China, caused by the novel reassortant avian-origin influenza A virus subtype H7N9. The ability to readily identify novel strains will allow a more rapid response, in order to reduce the spread of the disease and minimize the chance of a worldwide flu pandemic.
Dong-Hun Lee, Ji-Hoon Kim, Seong-Su Yuk, Jung-Hoon Kwon, Hyunseok Cho, Seung Yong Hwang, Hyun-Mi Kang, Youn-Jeong Lee, Sang-Won Lee, In-Soo Choi, Chang-Seon Song   +10 more
openaire   +1 more source

Hemagglutinin affects replication, stability and airborne transmission of the H9N2 subtype avian influenza virus.

Virology, 2023
H9N2 subtype avian influenza virus (AIV) can transmit by direct as well as airborne contacts. It has been widespread in poultry and continued to contribute to zoonotic spillover events by providing its six internal genes for the reassortment of novel ...
Naiqing Xu, Xinen Tang, Xin Wang, Miao Cai, Xiaowen Liu, Xiaolong Lu, Shunlin Hu, Min Gu, Jiao Hu, Ruyi Gao, Kaituo Liu, Yu Chen, Xiufan Liu, Xiaoquan Wang   +13 more
semanticscholar   +1 more source

Quadruple signal amplification strategy based on hybridization chain reaction and an immunoelectrode modified with graphene sheets, a hemin/G-quadruplex DNAzyme concatamer, and alcohol dehydrogenase: ultrasensitive determination of influenza virus subtype H7N9

Microchimica Acta, 2015
We report on a new amplification strategy for use in an immunoassay for influenza virus subtype H7N9. Graphene sheets were first placed on a glassy carbon electrode (GCE), and gold nanoparticles were then electrodeposited as a support for a layer of alcohol dehydrogenase (ADH) in a sol–gel containing thiol groups.
Juan Yang, Yu Xiang, Chao Song, Lingzhi Liu, Xiaoying Jing, Guoming Xie, Hua Xiang   +6 more
openaire   +1 more source

Construction of a monoclonal molecular imprinted sensor with high affinity for specific recognition of influenza a virus subtype.

Talanta: The International Journal of Pure and Applied Analytical Chemistry
Although molecular imprinting technology has been widely used in the construction of virus sensors, it is still a great challenge to identify subtypes viruses specifically because of their high similarity in morphology, size and structure.
H. Gong, Ganping Cai, Chunyan Chen, Feng Chen, Changqun Cai   +4 more
semanticscholar   +1 more source

Establishment of sandwich ELISA for detecting the H7 subtype influenza A virus

Journal of Medical Virology, 2019
Avian H7N9 subtype influenza virus infects human with high case‐fatality rate since it emerged in 2013. Although the vaccination has been rapidly used in poultry due to the emergence of highly pathogenic strain, this virus remains prevalent in this ...
Lingling Chen, Feier Ruan, Ying Sun, Haiying Chen, Mingbin Liu, Jian-fang Zhou, K. Qin   +6 more
semanticscholar   +1 more source

Neu5Gc binding loss of subtype H7 influenza A virus facilitates adaptation to gallinaceous poultry following transmission from waterbirds

Journal of Virology
Between 2013 and 2018, the novel A/Anhui/1/2013 (AH/13)-lineage H7N9 virus caused at least five waves of outbreaks in humans, totaling 1,567 confirmed human cases in China.
Minhui Guan, T. Deliberto, Aijing Feng, Jieze Zhang, Tao Li, Shuaishuai Wang, Lei Li, M. Killian, Beatriz Praena, Emily Giri, S. T. DeLiberto, J. Hang, Alicia Olivier, M. Torchetti, Yizhi Jane Tao, Colin R. Parrish, Xiu-Feng Wan   +16 more
semanticscholar   +1 more source

Dual N-linked glycosylation at residues 133 and 158 in the hemagglutinin are essential for the efficacy of H7N9 avian influenza virus like particle vaccine in chickens and mice.

Veterinary Microbiology
H7N9 subtype avian influenza virus (AIV) poses a great challenge to poultry industry. Virus-like particle (VLP) is a prospective alternative for the traditional egg-based influenza vaccines.
Yufei Wang, Qun Li, Peipei Peng, Qi Zhang, Yalan Huang, Jiao Hu, Zenglei Hu, Xiufan Liu   +7 more
semanticscholar   +1 more source

[Rapid detection of novel avian influenza virus subtype H7N9 by multiplex real-time RT-PCR].

Bing du xue bao = Chinese journal of virology, 2014
In order to develop a rapid detection kit for novel avian influenza virus (AIV) subtype H7N9, two sets of specific primers and probes were designed based on the nucleotide sequences of hemagglutinin antigen (HA) and neuraminidase antigen (NA) of novel H7N9 virus (2013) available in GenBank to establish the method of TaqMan probe-based multiplex real ...
Bao-Zheng, Luo, Qiu-Hua, Mo, Ru-Shu, Li, Qing-Ru, Bo, Hai-Nie, Xu, Cai-Hua, Sha, Xiu-Yun, Liao   +6 more
openaire   +1 more source

Generation and characterization of a nanobody against the avian influenza virus H7 subtype.

International Journal of Biological Macromolecules
Avian influenza virus (AIV) H7N9 diseases have been recently reported, raising concerns about a potential pandemic. Thus, there is an urgent need for effective therapeutics for AIV H7N9 infections.
Xiuqin Huang, Weiye Li, Xuewei Cao, Qi Zhang, Yizhen Lin, Siqi Xu, Xinying Dong, Peiqi Liu, Yutong Liu, Ge He, Kaijian Luo, Saixiang Feng   +11 more
semanticscholar   +1 more source