Results 211 to 220 of about 945,008 (390)

A NEW GENUS OF INFLUENZA VIRUS — Influenza D virus (review) [PDF]

Sel'skokhozyaistvennaya Biologiya, 2021
openaire   +1 more source

Constraints, Drivers, and Implications of Influenza A Virus Reassortment.

Annual Review of Virology, 2017
Anice C. Lowen
semanticscholar   +1 more source

Astrocytic PERK Deficiency Drives Prefrontal Circuit Dysfunction and Depressive‐Like Behaviors

Advanced Science, EarlyView.
Chen et al. show that the endoplasmic reticulum (ER) stress sensor PERK is downregulated in prefrontal cortex (PFC) astrocytes in major depressive disorder and in chronic‐stress mouse models. In young mice, astrocyte‐specific PERK loss reduces the synaptogenic cue thrombospondin‐1 (TSP1), leading to synaptic and circuit deficits and depressive‐like ...
Kai Chen, Riya Gupta, Yosuke M. Morizawa, Yu Qin, Xingyu Du, Cynthia Pang, Osama Al‐Dalahmah, Maura B. Dupont, Guang Yang   +8 more
wiley   +1 more source

Influenza A Virus [PDF]

, 2020
openaire   +1 more source

Subicular Astrocytes Govern Seizure‐Impaired Fear Memory

Advanced Science, EarlyView.
Astrocytes in dorsal subiculum act as a critical modulator of seizure‐associated cognitive dysfunction, operating through a Ca2+‐dependent adenosine‐linked astrocyte‐neuron signaling pathway that disrupts neuronal circuit homeostasis. This research highlights the potential of astrocyte‐targeted interventions as a therapeutic strategy, moving beyond the
Yuying Shao, Jing Xi, Yuhao Sun, Yulan Li, Zhisheng Li, Wangjialu Lu, Jialu Chen, Lin Yang, Fan Fei, Heming Cheng, Li Cheng, Cenglin Xu, Zhuo Huang, Vladimir Parpura, Yi Wang, Zhong Chen   +15 more
wiley   +1 more source

Influenza D Virus in Black Donkeys, Northern China. [PDF]

Emerg Infect Dis
Shen M, Yu J, Fu B, Yu C, Cui C, Chen S, Liu C, Wang K, Wang Z.   +8 more
europepmc   +1 more source

Microbiota regulates immune defense against respiratory tract influenza A virus infection

Proceedings of the National Academy of Sciences of the United States of America, 2011
T. Ichinohe, I. K. Pang, Yosuke Kumamoto, D. Peaper, J. Ho, T. Murray, A. Iwasaki   +6 more
semanticscholar   +1 more source

Potent and Long‐Lasting Immunogenicity Generated by LNP‐mRNA gE Antigen Against Varicella Zoster Virus via an AI‐Assisted Pipeline

Advanced Science, EarlyView.
This study designs a novel mRNA‐LNP vaccine targeting VZV glycoprotein E (gE) for herpes zoster via an AI‐assisted pipeline. Validated in mice and rhesus macaques, the mRNA‐LNP vaccine shows strong humoral and cellular immune responses, with CD4+ T‐cell responses more effective and durable than Shingrix, offering a promising prophylactic option ...
Kai Dong, Fang Liu, Dawei Wang, Yanfen Li, Man Zhang, Yuting Zhou, Gengshen Song   +6 more
wiley   +1 more source

Disruption of influenza A virus transmission in gene-edited pigs. [PDF]

Emerg Microbes Infect
Kwon T, Morozov I, McDowell CD, Lyoo EL, Artiaga BL, Li Y, Assato P, White SN, Beaton BP, Delhon G, Gaudreault NN, Richt JA.   +11 more
europepmc   +1 more source

The Disordered Region of ASXL1 Acts as an Auto‐Regulator Through Condensation

Advanced Science, EarlyView.
ASXL1's long IDR encodes an electrostatic “basic platform + acidic brake” that autoregulates condensation. Truncation at a clinical hotspot lifts this brake, forming condensates that retarget BRD2, remodel local chromatin accessibility, and impair neutrophil maturation.
Xiao Fang, Qiwei Li, Wenqing Zhang
wiley   +1 more source