Results 111 to 120 of about 261,869 (302)

Clinical Trials With Pragmatic Elements: A Review of Use Cases and Real‐World Data Utilization

open access: yesClinical Pharmacology &Therapeutics, EarlyView.
Clinical trials with pragmatic elements can capture diverse patient populations, enable efficient follow‐up, and reflect routine clinical practices; yet there is limited understanding of their design features, characteristics, and use of real‐world data (RWD). Based on a targeted search of PubMed/EMBASE (Jan‐2016 to Jul‐2024), a review was conducted to
Le Su   +6 more
wiley   +1 more source

Anti-influenza antibody level after vaccination in north of Iran [PDF]

open access: yes, 2009
Objective:Influenza is a highly transmitted disease and about 10% of the world's population is affected by this disease annually. The aim of this research was to study the variation of serum antibody levels among subjects who had already been vaccinated ...
Abbasi, A.   +3 more
core  

Clinical endpoints in pragmatic heart failure trials: From data collection to clinical endpoint classification

open access: yesESC Heart Failure, EarlyView.
Abstract Clinical endpoint classification (CEC)—that is, evaluation of clinical events using pre‐defined criteria—is commonly conducted in clinical trial operations to ensure systematic and consistent assessment of endpoints needed to assess the intervention's safety and efficacy.
Veraprapas Kittipibul   +13 more
wiley   +1 more source

Neuraminidase and resistance to vaccination with live influenza A2 Hong Kong vaccines [PDF]

open access: bronze, 1971
A. N. Slepushkin   +4 more
openalex   +1 more source

Socioeconomic determinants of vaccination against pneumococcus in 763 945 patients with heart failure

open access: yesESC Heart Failure, EarlyView.
Respiratory infections heighten risks for heart failure (HF) patients, yet 2020 data from France show low vaccination rates: 12.6% for pneumococcus and 63.1% for influenza. Using logistic regression on 763,945 HF patients, older age, female sex, and social deprivation were associated with lower pneumococcus vaccination, despite frequent healthcare ...
F. Roubille   +6 more
wiley   +1 more source

A Practical Approach to Implementing ICH Q14: Tools for Analytical Quality by Design in Capillary Electrophoresis Method Development

open access: yesELECTROPHORESIS, EarlyView.
ABSTRACT The ICH Q14 guideline introduces a structured framework for analytical method development based on Analytical Quality by Design (AQbD) principles, aiming to ensure robust, reliable, and fit‐for‐purpose methods throughout the product lifecycle.
Ewoud van Tricht   +1 more
wiley   +1 more source

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