Results 41 to 50 of about 885,970 (344)

The potential cost-effectiveness of quadrivalent versus trivalent influenza vaccine in elderly people and clinical risk groups in the UK: a lifetime multi-cohort model. [PDF]

PLoS ONE, 2014
To estimate the potential cost-effectiveness of quadrivalent influenza vaccine compared with trivalent influenza vaccine in the UK.A lifetime, multi-cohort, static Markov model was constructed, with nine age groups each divided into healthy and at-risk ...
Laure-Anne Van Bellinghen, Genevieve Meier, Ilse Van Vlaenderen   +2 more
doaj   +1 more source

Adjuvanted influenza vaccines [PDF]

Human Vaccines & Immunotherapeutics, 2012
The search for adjuvants has been stimulated by the need to ensure greater protection against influenza among subjects who show a reduced immune response to conventional influenza vaccines. Aluminum salts have long been used but are not considered satisfactory.
N. Principi, Esposito, Susanna Maria Roberta   +1 more
openaire   +7 more sources

Recombinant Influenza Vaccines [PDF]

Acta Naturae, 2012
This review covers the problems encountered in the construction and production of new recombinant influenza vaccines. New approaches to the development of influenza vaccines are investigated; they include reverse genetics methods, production of virus-like particles, and DNA- and viral vector-based vaccines.
Sedova, E., Shcherbinin, D., Migunov, A., Smirnov, Iu, Logunov, D., Shmarov, M., Tsybalova, L., Naroditskiĭ, B., Kiselev, O., Gintsburg, A.   +9 more
openaire   +4 more sources

The Usage of Influenza Vaccine to Prevent Seasonal Influenza during Pandemic COVID-19

Magna Medika, 2021
Influenza is an acute respiratory disease caused by influenza virus. Influenza can affect million people in every year and causing morbidity. Some of cases can be severe and need hospitalized, especially in elderly people.
Yelvi Levani, Ayu Lidya Paramita
doaj   +1 more source

Broadly Protective Strategies Against Influenza Viruses: Universal Vaccines and Therapeutics

Frontiers in Microbiology, 2020
Influenza virus is a respiratory pathogen that can cause disease in humans, with symptoms ranging from mild to life-threatening. The vast majority of influenza virus infections in humans are observed during seasonal epidemics and occasional pandemics ...
Olivia A. Vogel, Balaji Manicassamy
doaj   +1 more source

Applying valency-based immuno-selection to generate broadly cross-reactive antibodies against influenza hemagglutinins

Nature Communications
Conserved epitopes shared between virus subtypes are often subdominant, making it difficult to induce broadly reactive antibodies by immunization. Here, we generate a plasmid DNA mix vaccine that encodes protein heterodimers with sixteen different ...
Daniëla Maria Hinke, Ane Marie Anderson, Kirankumar Katta, Marlene Fyrstenberg Laursen, Demo Yemane Tesfaye, Ina Charlotta Werninghaus, Davide Angeletti, Gunnveig Grødeland, Bjarne Bogen, Ranveig Braathen   +9 more
doaj   +1 more source

Consolidate Overview of Ribonucleic Acid Molecular Dynamics: From Molecular Movements to Material Innovations

Advanced Engineering Materials, EarlyView.
Molecular dynamics simulations are advancing the study of ribonucleic acid (RNA) and RNA‐conjugated molecules. These developments include improvements in force fields, long‐timescale dynamics, and coarse‐grained models, addressing limitations and refining methods.
Kanchan Yadav, Iksoo Jang, Jong Bum Lee
wiley   +1 more source

Adjuvanted influenza vaccines [PDF]

Human Vaccines & Immunotherapeutics, 2018
In spite of current influenza vaccines being immunogenic, evolution of the influenza virus can reduce efficacy and so influenza remains a major threat to public health. One approach to improve influenza vaccines is to include adjuvants; substances that boost the immune response.
John S. Tregoning, Ryan F. Russell, Ekaterina Kinnear   +2 more
openaire   +6 more sources

Interim Estimates of 2018–19 Seasonal Influenza Vaccine Effectiveness — United States, February 2019

MMWR. Morbidity and mortality weekly report, 2019
In the United States, annual vaccination against seasonal influenza is recommended for all persons aged ≥6 months (https://www.cdc.gov/flu/protect/whoshouldvax.htm). Effectiveness of seasonal influenza vaccine varies by season.
J. Doyle, J. Chung, Sara S. Kim, M. Gaglani, Chandni Raiyani, R. Zimmerman, M. Nowalk, M. Jackson, L. Jackson, A. Monto, E. Martin, E. Belongia, H. McLean, Angie Foust, W. Sessions, L. Berman, R. Garten, J. Barnes, D. Wentworth, A. Fry, Manish M Patel, B. Flannery   +21 more
semanticscholar   +1 more source

Time‐Controlled Dual Targeting to Program Systemic and Intercellular Transfer of Therapeutic Effects

Advanced Functional Materials, EarlyView.
Aspirin‐liposomes loaded onto monocytes enable inflammation‐triggered targeting and efficient hand‐over of aspirin to inflamed cells. Monocytes uptake a significant portion of aspirin‐liposomes, prolonging therapeutic action. This approach enhances anti‐inflammatory effects through intercellular transfer, demonstrating a translational strategy for ...
Seung Eun Yu, Jueun Kim, Dae‐Hyun Kim, Sewoom Baek, Suji Park, Seyong Chung, Hak‐Joon Sung   +6 more
wiley   +1 more source