Results 61 to 70 of about 282,997 (350)
Roadblocks to translational challenges on viral pathogenesis. [PDF]
, 2013 Distinct roadblocks prevent translating basic findings in viral pathogenesis into therapies and implementing potential solutions in the clinic. An ongoing partnership between the Volkswagen Foundation and Nature Medicine resulted in an interactive ...
Deeks, Steven +4 more
core +1 more source
A Live Probiotic Vaccine Prototype Based on Conserved Influenza a Virus Antigens Protect Mice against Lethal Influenza Virus Infection [PDF]
, 2021 Daria Mezhenskaya +8 more
openalex +1 more source
Advanced Healthcare Materials, EarlyView.This study explores nanoparticle delivery of the protein kinase C inhibitor bisindolylmaleimide‐I (BIM‐I) to combat influenza A virus infections. Encapsulation in biodegradable PLGA nanoparticles improved safety while maintaining the compound's strong antiviral activity.
Laura Klement +12 more
wiley +1 more source
Frontiers in Public HealthBackgroundSeasonal Influenza is a major cause of morbidity and mortality worldwide. Despite the well-established preventive role of the influenza vaccine particularly for patients at high risk, influenza vaccine uptake remains suboptimal. In Jordan, data
Munir Abu-Helalah +10 more
doaj +1 more source
Effectiveness of A(H1N1)pdm09 influenza vaccine in adults recommended for annual influenza vaccination. [PDF]
PLoS ONE, 2013 INTRODUCTION: Because of variability in published A(H1N1)pdm09 influenza vaccine effectiveness estimates, we conducted a study in the adults belonging to the risk groups to assess the A(H1N1)pdm09 MF59-adjuvanted influenza vaccine effectiveness. METHODS:
Giedre Gefenaite +11 more
doaj +1 more source
Saudi Pharmaceutical Journal, 2022 The global coronavirus disease (COVID-19) epidemic can be partially managed by vaccines; however, the public must be informed about the safety of COVID-19 vaccines to avoid hesitancy.
Abdullah K. Al-Ahmari +7 more
doaj +1 more source
Chemical-free inactivated whole influenza virus vaccine prepared by ultrashort pulsed laser treatment [PDF]
, 2014 There is an urgent need for rapid methods to develop vaccines in response to emerging viral pathogens. Whole inactivated virus (WIV) vaccines represent an ideal strategy for this purpose; however, a universal method for producing safe and immunogenic ...
Achilefu, Samuel +10 more
core +2 more sources
Influenza vaccine efficacy [PDF]
Canadian Medical Association Journal, 2015 I am writing in response to a recent news article[1][1] published in CMAJ . The lack of efficacy of this year’s vaccine preparation is often used as an argument against vaccination. Although the match between the vaccine H3N2 strain and the circulating H3N2 wild-type may not be optimum, we ...
openaire +2 more sources
Advanced Healthcare Materials, EarlyView.This study presents guanidinium‐ and indole‐functionalized polyphosphoesters as degradable, non‐viral gene delivery vectors. Through precise tuning of charge density and hydrophobicity, these polymers form stable polyplexes with low toxicity. Remarkably, minor structural changes yield up to 200‐fold differences in transfection efficiency, highlighting ...
Markus Kötzsche +8 more
wiley +1 more source