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Advances in Development and Application of Influenza Vaccines
Influenza A virus is one of the most important zoonotic pathogens that can cause severe symptoms and has the potential to cause high number of deaths and great economic loss.
Jidang Chen +3 more
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Influenza is a vaccine preventable disease and vaccination remains the most effective method of controlling the morbidity and mortality of seasonal influenza, especially with respect to risk groups.
Claudia Maria Trombetta +4 more
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Development and Regulation of Novel Influenza Virus Vaccines: A United States Young Scientist Perspective [PDF]
Vaccination against influenza is the most effective approach for reducing influenza morbidity and mortality. However, influenza vaccines are unique among all licensed vaccines as they are updated and administered annually to antigenically match the ...
Surender Khurana
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Adjuvantation of Influenza Vaccines to Induce Cross-Protective Immunity
Influenza poses a huge threat to global public health. Influenza vaccines are the most effective and cost-effective means to control influenza. Current influenza vaccines mainly induce neutralizing antibodies against highly variable globular head of ...
Zhuofan Li +3 more
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Influenza and Memory T Cells: How to Awake the Force [PDF]
Annual influenza vaccination is an effective way to prevent human influenza. Current vaccines are mainly focused on eliciting a strain-matched humoral immune response, requiring yearly updates, and do not provide protection for all vaccinated individuals ...
Jan Spitaels +2 more
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Advances in Adjuvanted Influenza Vaccines
The numerous influenza infections that occur every year present a major public health problem. Influenza vaccines are important for the prevention of the disease; however, their effectiveness against infection can be suboptimal.
Shintaro Shichinohe, Tokiko Watanabe
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The influenza vaccine is not included in China’s national immunization program. Here, we assessed influenza vaccine coverage among Shanghai residents and estimated the impacts of the coronavirus disease 2019 (COVID-19) epidemic and a hypothetical free ...
Yehong Zhou +3 more
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Adenoviral Vector-Based Vaccine Platforms for Developing the Next Generation of Influenza Vaccines
Ever since the discovery of vaccines, many deadly diseases have been contained worldwide, ultimately culminating in the eradication of smallpox and polio, which represented significant medical achievements in human health.
Ekramy E. Sayedahmed +4 more
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In spite of current influenza vaccines being immunogenic, evolution of the influenza virus can reduce efficacy and so influenza remains a major threat to public health.
John S. Tregoning +2 more
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Prospects and Challenges in the Development of Universal Influenza Vaccines
Current influenza vaccines offer suboptimal protection and depend on annual reformulation and yearly administration. Vaccine technology has rapidly advanced during the last decade, facilitating development of next-generation influenza vaccines that can ...
Anders Madsen, Rebecca Jane Cox
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