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Influenza and Memory T Cells: How to Awake the Force [PDF]
Vaccines, 2016 Annual influenza vaccination is an effective way to prevent human influenza. Current vaccines are mainly focused on eliciting a strain-matched humoral immune response, requiring yearly updates, and do not provide protection for all vaccinated individuals ...
Jan Spitaels +2 more
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Adjuvanted influenza vaccines [PDF]
Human Vaccines & Immunotherapeutics, 2018 In spite of current influenza vaccines being immunogenic, evolution of the influenza virus can reduce efficacy and so influenza remains a major threat to public health.
John S. Tregoning +2 more
doaj +5 more sources
npj Vaccines, 2021 Influenza viruses cause annual seasonal epidemics and sporadic pandemics; vaccination is the most effective countermeasure. Intranasal live attenuated influenza vaccines (LAIVs) are needle-free, mimic the natural route of infection, and elicit robust ...
Jasmina M. Luczo +12 more
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Vaccine, 2009 Influenza A viruses pose a substantial threat to the human population whether by purposeful manipulation and release or by the natural process of interspecies transmissions from animal reservoirs. The challenge with preparing for these events with vaccination strategies is that the best forms of protective immunity target the most variable of the viral
A H, Ellebedy, R J, Webby
openaire +2 more sources
Molecular Therapy: Methods & Clinical Development, 2020 Immunogenicity of DNA vaccines can be increased by constructing the DNA in such a way that it encodes secreted homodimeric fusion proteins that target antigen-presenting cells (APCs). In this study, we have developed novel APC-targeting vaccine molecules
Ranveig Braathen +6 more
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Frontiers in Immunology, 2022 Targeting antigen to conventional dendritic cells (cDCs) can improve antigen-specific immune responses and additionally be used to influence the polarization of the immune responses. However, the mechanisms by which this is achieved are less clear.
Demo Yemane Tesfaye +16 more
doaj +1 more source
Advances in Development and Application of Influenza Vaccines
Frontiers in Immunology, 2021 Influenza A virus is one of the most important zoonotic pathogens that can cause severe symptoms and has the potential to cause high number of deaths and great economic loss.
Jidang Chen +3 more
doaj +1 more source
DNA Vaccines Encoding Antigen Targeted to MHC Class II Induce Influenza-Specific CD8+ T Cell Responses, Enabling Faster Resolution of Influenza Disease [PDF]
, 2016 Current influenza vaccines are effective but imperfect, failing to cover against emerging strains of virus and requiring seasonal administration to protect against new strains. A key step to improving influenza vaccines is to improve our understanding of
Bogen, B +8 more
core +7 more sources
Annals of Saudi Medicine, 1999 Nurses have an important part to play in dispelling myths about influenza vaccination and in actively encouraging older people to attend for vaccination. Irene Schofield discusses the issues.
A, Uma, P, Thirumalaikolundusubramanian
openaire +5 more sources
Solid bioneedle-delivered influenza vaccines are highly thermostable and induce both humoral and cellular immune responses. [PDF]
PLoS ONE, 2014 The potential of bioneedles to deliver influenza vaccines was investigated. Four influenza vaccine formulations were screened to determine the optimal formulation for use with bioneedles.
Peter C Soema +6 more
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