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Adjuvanted influenza vaccines [PDF]
Human Vaccines & Immunotherapeutics, 2018 In spite of current influenza vaccines being immunogenic, evolution of the influenza virus can reduce efficacy and so influenza remains a major threat to public health.
John S. Tregoning +2 more
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Adjuvantation of Influenza Vaccines to Induce Cross-Protective Immunity [PDF]
Vaccines, 2021 Influenza poses a huge threat to global public health. Influenza vaccines are the most effective and cost-effective means to control influenza. Current influenza vaccines mainly induce neutralizing antibodies against highly variable globular head of ...
Zhuofan Li +3 more
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Prospects and Challenges in the Development of Universal Influenza Vaccines [PDF]
Vaccines, 2020 Current influenza vaccines offer suboptimal protection and depend on annual reformulation and yearly administration. Vaccine technology has rapidly advanced during the last decade, facilitating development of next-generation influenza vaccines that can ...
Anders Madsen, Rebecca Jane Cox
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Advances in Development and Application of Influenza Vaccines
Frontiers in Immunology, 2021 Influenza A virus is one of the most important zoonotic pathogens that can cause severe symptoms and has the potential to cause high number of deaths and great economic loss.
Jidang Chen +3 more
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Vaccines, 2022 Influenza is a vaccine preventable disease and vaccination remains the most effective method of controlling the morbidity and mortality of seasonal influenza, especially with respect to risk groups.
Claudia Maria Trombetta +4 more
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Cell culture-derived flu vaccine: Present and future [PDF]
Human Vaccines & Immunotherapeutics, 2018 The benefit of influenza vaccines is difficult to estimate due to the complexity of accurately assessing the burden of influenza. To improve the efficacy of influenza vaccines, vaccine manufacturers have developed quadrivalent influenza vaccine (QIV ...
Alberto Pérez Rubio, Jose María Eiros
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Advances in Nucleic Acid Universal Influenza Vaccines [PDF]
VaccinesCurrently, vaccination with influenza vaccines is still an effective strategy to prevent infection by seasonal influenza virus in spite of some drawbacks with them.
Liang Xu +3 more
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Universal or Specific? A Modeling-Based Comparison of Broad-Spectrum Influenza Vaccines against Conventional, Strain-Matched Vaccines. [PDF]
PLoS Computational Biology, 2016 Despite the availability of vaccines, influenza remains a major public health challenge. A key reason is the virus capacity for immune escape: ongoing evolution allows the continual circulation of seasonal influenza, while novel influenza viruses invade ...
Rahul Subramanian +3 more
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Adenoviral Vector-Based Vaccine Platforms for Developing the Next Generation of Influenza Vaccines
Vaccines, 2020 Ever since the discovery of vaccines, many deadly diseases have been contained worldwide, ultimately culminating in the eradication of smallpox and polio, which represented significant medical achievements in human health.
Ekramy E. Sayedahmed +4 more
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An Overview of Influenza Viruses and Vaccines
Vaccines, 2021 Influenza remains one of the major public health concerns because it causes annual epidemics and can potentially instigate a global pandemic. Numerous countermeasures, including vaccines and antiviral treatments, are in use against seasonal influenza ...
Rina Fajri Nuwarda +2 more
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