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Adjuvanted influenza vaccines [PDF]

Human Vaccines & Immunotherapeutics, 2018
In spite of current influenza vaccines being immunogenic, evolution of the influenza virus can reduce efficacy and so influenza remains a major threat to public health.
John S. Tregoning, Ryan F. Russell, Ekaterina Kinnear   +2 more
doaj   +7 more sources

Influenza and Memory T Cells: How to Awake the Force [PDF]

Vaccines, 2016
Annual influenza vaccination is an effective way to prevent human influenza. Current vaccines are mainly focused on eliciting a strain-matched humoral immune response, requiring yearly updates, and do not provide protection for all vaccinated individuals ...
Jan Spitaels, Kenny Roose, Xavier Saelens   +2 more
doaj   +4 more sources

Advances in Nucleic Acid Universal Influenza Vaccines [PDF]

Vaccines
Currently, vaccination with influenza vaccines is still an effective strategy to prevent infection by seasonal influenza virus in spite of some drawbacks with them.
Liang Xu, Weigang Ren, Qin Wang, Junwei Li   +3 more
doaj   +2 more sources

The need for novel influenza vaccines in low- and middle-income countries: A narrative review [PDF]

Brazilian Journal of Infectious Diseases
Influenza viruses cause 3–5 million severe cases and 300,000–600,000 deaths worldwide. Most of the disease burden is in Low- and Middle-Income Countries (LMICs) owing to factors such as high population density, infrastructure challenges, poor quality ...
Julia R. Spinardi, Karan B. Thakkar, Verna L. Welch, Oladayo Jagun, Moe H. Kyaw   +4 more
doaj   +2 more sources

Vaccines for Influenza [PDF]

Vaccines, 2021
Two reviews by Harding and Heaton [...]
Apostolos P. Georgopoulos, Apostolos P. Georgopoulos, Spyros Charonis, Spyros Charonis, Effie Photini C. Tsilibary   +4 more
openaire   +3 more sources

Influenza Vaccines

Nature Reviews Drug Discovery, 2006
Mark J, Belsey, Brigitte, de Lima, Alex K, Pavlou, John W, Savopoulos   +3 more
europepmc   +3 more sources

Influenza Virus and Vaccination [PDF]

Pathogens, 2020
Influenza virus infections represent a serious public health problem causing contagious respiratory disease and substantial morbidity and mortality in humans, resulting in a considerable economic burden worldwide. Notably, the number of deaths due to influenza exceeds that of any other known pathogen.
Aitor Nogales, Marta L. DeDiego
openaire   +6 more sources

Intranasal powder live attenuated influenza vaccine is thermostable, immunogenic, and protective against homologous challenge in ferrets

npj Vaccines, 2021
Influenza viruses cause annual seasonal epidemics and sporadic pandemics; vaccination is the most effective countermeasure. Intranasal live attenuated influenza vaccines (LAIVs) are needle-free, mimic the natural route of infection, and elicit robust ...
Jasmina M. Luczo, Tatiana Bousse, Scott K. Johnson, Cheryl A. Jones, Nicholas Pearce, Carlie A. Neiswanger, Min-Xuan Wang, Erin A. Miller, Nikolai Petrovsky, David E. Wentworth, Victor Bronshtein, Mark Papania, Stephen M. Tompkins   +12 more
doaj   +1 more source

Influenza and the influenza vaccine [PDF]

Canadian Medical Association Journal, 2007
Influenza, or the “flu,” is an infection caused by the influenza virus. The virus infects the nose and throat, and it can sometimes spread to the lungs. Influenza commonly causes acute fever, cough, chills, tiredness, body aches and, in young children, ear aches.
Joanne M. Langley, Erica Weir, Noni E. MacDonald   +2 more
openaire   +3 more sources

Targeting Xcr1 on Dendritic Cells Rapidly Induce Th1-Associated Immune Responses That Contribute to Protection Against Influenza Infection

Frontiers in Immunology, 2022
Targeting antigen to conventional dendritic cells (cDCs) can improve antigen-specific immune responses and additionally be used to influence the polarization of the immune responses. However, the mechanisms by which this is achieved are less clear.
Demo Yemane Tesfaye, Demo Yemane Tesfaye, Sonja Bobic, Sonja Bobic, Anna Lysén, Anna Lysén, Peter Csaba Huszthy, Peter Csaba Huszthy, Arnar Gudjonsson, Arnar Gudjonsson, Ranveig Braathen, Ranveig Braathen, Bjarne Bogen, Bjarne Bogen, Bjarne Bogen, Even Fossum, Even Fossum   +16 more
doaj   +1 more source