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Advances in Nucleic Acid Universal Influenza Vaccines [PDF]

Vaccines
Currently, vaccination with influenza vaccines is still an effective strategy to prevent infection by seasonal influenza virus in spite of some drawbacks with them.
Liang Xu, Weigang Ren, Qin Wang, Junwei Li   +3 more
doaj   +2 more sources

Adjuvanted influenza vaccines [PDF]

Human Vaccines & Immunotherapeutics, 2018
In spite of current influenza vaccines being immunogenic, evolution of the influenza virus can reduce efficacy and so influenza remains a major threat to public health.
John S. Tregoning, Ryan F. Russell, Ekaterina Kinnear   +2 more
doaj   +6 more sources

The need for novel influenza vaccines in low- and middle-income countries: A narrative review [PDF]

Brazilian Journal of Infectious Diseases
Influenza viruses cause 3–5 million severe cases and 300,000–600,000 deaths worldwide. Most of the disease burden is in Low- and Middle-Income Countries (LMICs) owing to factors such as high population density, infrastructure challenges, poor quality ...
Julia R. Spinardi, Karan B. Thakkar, Verna L. Welch, Oladayo Jagun, Moe H. Kyaw   +4 more
doaj   +2 more sources

Vaccines for Influenza [PDF]

Vaccines, 2021
Two reviews by Harding and Heaton [...]
Apostolos P. Georgopoulos, Apostolos P. Georgopoulos, Spyros Charonis, Spyros Charonis, Effie Photini C. Tsilibary   +4 more
openaire   +3 more sources

Influenza Vaccines

Nature Reviews Drug Discovery, 2006
Mark J, Belsey, Brigitte, de Lima, Alex K, Pavlou, John W, Savopoulos   +3 more
europepmc   +3 more sources

Influenza Virus and Vaccination [PDF]

Pathogens, 2020
Influenza virus infections represent a serious public health problem causing contagious respiratory disease and substantial morbidity and mortality in humans, resulting in a considerable economic burden worldwide. Notably, the number of deaths due to influenza exceeds that of any other known pathogen.
Aitor Nogales, Marta L. DeDiego
openaire   +6 more sources

Intranasal powder live attenuated influenza vaccine is thermostable, immunogenic, and protective against homologous challenge in ferrets

npj Vaccines, 2021
Influenza viruses cause annual seasonal epidemics and sporadic pandemics; vaccination is the most effective countermeasure. Intranasal live attenuated influenza vaccines (LAIVs) are needle-free, mimic the natural route of infection, and elicit robust ...
Jasmina M. Luczo, Tatiana Bousse, Scott K. Johnson, Cheryl A. Jones, Nicholas Pearce, Carlie A. Neiswanger, Min-Xuan Wang, Erin A. Miller, Nikolai Petrovsky, David E. Wentworth, Victor Bronshtein, Mark Papania, Stephen M. Tompkins   +12 more
doaj   +1 more source

Influenza and the influenza vaccine [PDF]

Canadian Medical Association Journal, 2007
Influenza, or the “flu,” is an infection caused by the influenza virus. The virus infects the nose and throat, and it can sometimes spread to the lungs. Influenza commonly causes acute fever, cough, chills, tiredness, body aches and, in young children, ear aches.
Joanne M. Langley, Erica Weir, Noni E. MacDonald   +2 more
openaire   +3 more sources

Advances in Development and Application of Influenza Vaccines

Frontiers in Immunology, 2021
Influenza A virus is one of the most important zoonotic pathogens that can cause severe symptoms and has the potential to cause high number of deaths and great economic loss.
Jidang Chen, Jiehuang Wang, Jipei Zhang, Hinh Ly   +3 more
doaj   +1 more source

Solid bioneedle-delivered influenza vaccines are highly thermostable and induce both humoral and cellular immune responses. [PDF]

PLoS ONE, 2014
The potential of bioneedles to deliver influenza vaccines was investigated. Four influenza vaccine formulations were screened to determine the optimal formulation for use with bioneedles.
Peter C Soema, Geert-Jan Willems, Klaas van Twillert, Gijsbert van de Wijdeven, Claire J Boog, Gideon F A Kersten, Jean-Pierre Amorij   +6 more
doaj   +1 more source