Results 1 to 10 of about 121,065 (163)

Advances in Development and Application of Influenza Vaccines

Frontiers in Immunology, 2021
Influenza A virus is one of the most important zoonotic pathogens that can cause severe symptoms and has the potential to cause high number of deaths and great economic loss.
Hinh Ly, Jidang Chen, Ly Hinh
exaly   +3 more sources

Cross-protection against highly pathogenic avian influenza H5N1 virus from seasonal influenza vaccines: a systematic review and meta-analysis of ferret studies [PDF]

Emerging Microbes and Infections
The recent surge in spillover events of highly pathogenic avian influenza A(H5N1) clade 2.3.4.4b to humans and mammals in North America has raised urgent pandemic concerns. Human H5N1 vaccines are unavailable in most countries.
IShin Tseng, Ying-Chi Huang, Wei-Liang Shih, Chung-Hsi Chou, Sten H. Vermund, Chi-Tai Fang   +5 more
doaj   +2 more sources

M2e-Based Universal Influenza A Vaccines

Vaccines, 2015
The successful isolation of a human influenza virus in 1933 was soon followed by the first attempts to develop an influenza vaccine. Nowadays, vaccination is still the most effective method to prevent human influenza disease.
, Xavier Saelens, Saelens Xavier
exaly   +3 more sources

Vaccines for Influenza [PDF]

Vaccines, 2021
Two reviews by Harding and Heaton [...]
Effie-Photini Tsilibary, Spyros A. Charonis, Apostolos P. Georgopoulos   +2 more
openaire   +3 more sources

Influenza Vaccines

Nature Reviews Drug Discovery, 2006
Mark J, Belsey, Brigitte, de Lima, Alex K, Pavlou, John W, Savopoulos   +3 more
europepmc   +3 more sources

Influenza vaccines [PDF]

Vaccine, 2009
Influenza A viruses pose a substantial threat to the human population whether by purposeful manipulation and release or by the natural process of interspecies transmissions from animal reservoirs. The challenge with preparing for these events with vaccination strategies is that the best forms of protective immunity target the most variable of the viral
A H, Ellebedy, R J, Webby
openaire   +4 more sources

Influenza and the influenza vaccine [PDF]

Canadian Medical Association Journal, 2007
Influenza, or the “flu,” is an infection caused by the influenza virus. The virus infects the nose and throat, and it can sometimes spread to the lungs. Influenza commonly causes acute fever, cough, chills, tiredness, body aches and, in young children, ear aches.
Noni, MacDonald, Erica, Weir, Joanne M, Langley   +2 more
openaire   +2 more sources

Intranasal powder live attenuated influenza vaccine is thermostable, immunogenic, and protective against homologous challenge in ferrets

npj Vaccines, 2021
Influenza viruses cause annual seasonal epidemics and sporadic pandemics; vaccination is the most effective countermeasure. Intranasal live attenuated influenza vaccines (LAIVs) are needle-free, mimic the natural route of infection, and elicit robust ...
Jasmina M. Luczo, Tatiana Bousse, Scott K. Johnson, Cheryl A. Jones, Nicholas Pearce, Carlie A. Neiswanger, Min-Xuan Wang, Erin A. Miller, Nikolai Petrovsky, David E. Wentworth, Victor Bronshtein, Mark Papania, Stephen M. Tompkins   +12 more
doaj   +1 more source

A DNA Vaccine That Encodes an Antigen-Presenting Cell-Specific Heterodimeric Protein Protects against Cancer and Influenza

Molecular Therapy: Methods & Clinical Development, 2020
Immunogenicity of DNA vaccines can be increased by constructing the DNA in such a way that it encodes secreted homodimeric fusion proteins that target antigen-presenting cells (APCs). In this study, we have developed novel APC-targeting vaccine molecules
Ranveig Braathen, Heidi Cecilie Larsen Spång, Daniëla Maria Hinke, Jana Blazevski, Sonja Bobic, Even Fossum, Bjarne Bogen   +6 more
doaj   +1 more source

Targeting Xcr1 on Dendritic Cells Rapidly Induce Th1-Associated Immune Responses That Contribute to Protection Against Influenza Infection

Frontiers in Immunology, 2022
Targeting antigen to conventional dendritic cells (cDCs) can improve antigen-specific immune responses and additionally be used to influence the polarization of the immune responses. However, the mechanisms by which this is achieved are less clear.
Demo Yemane Tesfaye, Demo Yemane Tesfaye, Sonja Bobic, Sonja Bobic, Anna Lysén, Anna Lysén, Peter Csaba Huszthy, Peter Csaba Huszthy, Arnar Gudjonsson, Arnar Gudjonsson, Ranveig Braathen, Ranveig Braathen, Bjarne Bogen, Bjarne Bogen, Bjarne Bogen, Even Fossum, Even Fossum   +16 more
doaj   +1 more source