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Solid bioneedle-delivered influenza vaccines are highly thermostable and induce both humoral and cellular immune responses. [PDF]
The potential of bioneedles to deliver influenza vaccines was investigated. Four influenza vaccine formulations were screened to determine the optimal formulation for use with bioneedles.
Peter C Soema +6 more
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Advances in Development and Application of Influenza Vaccines
Influenza A virus is one of the most important zoonotic pathogens that can cause severe symptoms and has the potential to cause high number of deaths and great economic loss.
Jidang Chen +3 more
doaj +3 more sources
Two reviews by Harding and Heaton [...]
Effie-Photini Tsilibary +2 more
openaire +3 more sources
Influenza A viruses pose a substantial threat to the human population whether by purposeful manipulation and release or by the natural process of interspecies transmissions from animal reservoirs. The challenge with preparing for these events with vaccination strategies is that the best forms of protective immunity target the most variable of the viral
A H, Ellebedy, R J, Webby
openaire +4 more sources
Influenza and the influenza vaccine [PDF]
Influenza, or the “flu,” is an infection caused by the influenza virus. The virus infects the nose and throat, and it can sometimes spread to the lungs. Influenza commonly causes acute fever, cough, chills, tiredness, body aches and, in young children, ear aches.
Noni, MacDonald +2 more
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Influenza viruses cause annual seasonal epidemics and sporadic pandemics; vaccination is the most effective countermeasure. Intranasal live attenuated influenza vaccines (LAIVs) are needle-free, mimic the natural route of infection, and elicit robust ...
Jasmina M. Luczo +12 more
doaj +1 more source
Immunogenicity of DNA vaccines can be increased by constructing the DNA in such a way that it encodes secreted homodimeric fusion proteins that target antigen-presenting cells (APCs). In this study, we have developed novel APC-targeting vaccine molecules
Ranveig Braathen +6 more
doaj +1 more source
Targeting antigen to conventional dendritic cells (cDCs) can improve antigen-specific immune responses and additionally be used to influence the polarization of the immune responses. However, the mechanisms by which this is achieved are less clear.
Demo Yemane Tesfaye +16 more
doaj +1 more source
Influenza and Influenza Vaccine: A Review [PDF]
AbstractInfluenza is a highly contagious, deadly virus, killing nearly half a million people yearly worldwide. The classic symptoms of influenza are fever, fatigue, cough, and body aches. In the outpatient setting, diagnosis can be made by clinical presentation with optional confirmatory diagnostic testing.
Cynthia Nypaver +2 more
openaire +2 more sources
Agent-based model of the impact of higher influenza vaccine efficacy on seasonal influenza burden
Introduction: Current influenza vaccines have limited effectiveness. COVID-19 vaccines using mRNA technology have demonstrated very high efficacy, suggesting that mRNA vaccines could be more effective for influenza. Several such influenza vaccines are in
Mary G. Krauland +6 more
doaj +1 more source

