Results 101 to 110 of about 207,197 (306)
Novel Platforms for the Development of a Universal Influenza Vaccine
Frontiers in Immunology, 2018 Despite advancements in immunotherapeutic approaches, influenza continues to cause severe illness, particularly among immunocompromised individuals, young children, and elderly adults.
Arun Kumar +5 more
doaj +1 more source
Pandemic Influenza: Ethics, Law, and the Public\u27s Health [PDF]
, 2007 Highly pathogenic Influenza (HPAI) has captured the close attention of policy makers who regard pandemic influenza as a national security threat. Although the prevalence is currently very low, recent evidence that the 1918 pandemic was caused by an avian
Berkman, Benjamin E. +1 more
core +1 more source
Advanced Science, EarlyView.Dual priming with minocycline and photodynamic priming reprograms the pancreatic tumor microenvironment to overcome chemoresistance. By suppressing DNA repair enzyme Tdp1, inducing photooxidative damage, and enhancing irinotecan delivery via light‐activated nanoencapsulation, this strategy remodels the tumor microenvironment and drives immune ...
Fernanda V. Cabral +7 more
wiley +1 more source
Prevention of infectious diseases in athletes. [PDF]
, 2007 The sports medicine physician may face challenging issues regarding infectious diseases when dealing with teams or highly competitive athletes who have difficulties taking time off to recover.
d'Hemecourt, Pierre, Luke, Anthony
core
Advanced Science, EarlyView.By leveraging this homodimerization mechanism, molecular glues were rationally designed to induce dysfunctional 3A dimerization, thereby restoring antiviral RNAi. The optimal molecular glue, VTP‐32, demonstrated potent and pan‐enterovirus (groups A, B, D) antiviral effects.
Yuan Fang +13 more
wiley +1 more source
Setting priorities for development of emerging interventions against childhood pneumonia, meningitis and influenza [PDF]
, 2012 WAcute lower respiratory infections, which broadly include pneumonia and bronchiolitis, are still the leading cause of childhood mortality. ALRI contributed to 18% of all deaths in children younger than five years of age in 2008, and the main pathogens ...
Black +21 more
core +3 more sources
A Catalytic Osmium Redox Couple Collapses Cancer Redox Balance
Advanced Science, EarlyView.A stable Os(III)/Os(IV) redox couple is developed to disrupt the tumor cell redox balance by concurrently catalyzing ROS generation and GSH depletion. Osmium‐treated cells exhibit multiple cell death pathways, including apoptosis, ferroptosis, and immunogenic cell death.
Wan‐Qiong Huang +9 more
wiley +1 more source
Pandemic Influenza: Warning, Children At-Risk [PDF]
, 2007 Identifies gaps in U.S. preparedness for treating and caring for children during a potential pandemic flu outbreak. Makes recommendations for appropriate doses of vaccine and medications and the management and treatment of children who become ...
core
Characterization of potential biomarkers of reactogenicity of licensed antiviral vaccines: randomized controlled clinical trials conducted by the BIOVACSAFE consortium [PDF]
, 2019 Funding text The authors are grateful for the vital contributions of the participating study volunteers, clinicians, nurses, and laboratory technicians at the Surrey study site.
Bodinham, C. +16 more
core +1 more source
Influenza Vaccine Progress [PDF]
Hospital Pharmacy, 2013 I have devoted several Hospital Pharmacy editorials1-4 to the safety and ethical concerns of vaccine use. I reported on a rigorous analysis5 that raised questions regarding the evidence for effectiveness of the present generation of influenza vaccines in the elderly and those at risk for medical complications.
openaire +2 more sources