Results 121 to 130 of about 967,275 (342)

Novel Approaches for The Development of Live Attenuated Influenza Vaccines

Viruses, 2019
Influenza virus still represents a considerable threat to global public health, despite the advances in the development and wide use of influenza vaccines.
P. Blanco-Lobo, A. Nogales, Laura Rodríguez, L. Martínez-Sobrido   +3 more
semanticscholar   +1 more source

ZNF33B Promotes Japanese Encephalitis Virus Infection by Regulating the Stability of M6A‐Modified Trim25 to Control the Autophagy Process

Advanced Science, EarlyView.
Upon JEV infection, ZNF33B recruits METTL14 to stabilize the METTL3‐METTL14 m6A methyltransferase complex, leading to increased m6A modification of host transcripts, including Trim25 mRNA. ZNF33B selectively binds m6A‐modified sites on Trim25 mRNA and accelerates its decay, resulting in reduced TRIM25 protein abundance.
Jian Du, Chunwei Li, Jiyuan Luo, Huizhi Zhang, Jinyan Zhang, Suya Wang, Huanchun Chen, Hongli Xu, Xiangmin Li, Ping Qian   +9 more
wiley   +1 more source

Influenza and Memory T Cells: How to Awake the Force

Vaccines, 2016
Annual influenza vaccination is an effective way to prevent human influenza. Current vaccines are mainly focused on eliciting a strain-matched humoral immune response, requiring yearly updates, and do not provide protection for all vaccinated individuals ...
Jan Spitaels, Kenny Roose, Xavier Saelens   +2 more
doaj   +1 more source

Real‐Time and Non‐Invasive Detection of Respiratory Viral Infections Using an Intelligent Odor Monitoring System (IOMS)

Advanced Science, EarlyView.
An intelligent odor monitoring system integrates an IVC animal model, gas sensor array, real‐time resistance readout, and machine‐learning analysis to continuously monitor infection‐associated odor changes. The platform captures longitudinal sensor responses, distinguishes infected from healthy states, and supports early‐stage respiratory viral ...
Yajie Shen, Weifeng Yuan, Long Li, Yucheng Zheng, Kenan Liu, Hegeng Li, Hua‐Yao Li, Yongliang Zhao, Binzhou Ying, Lanpeng Guo, Wenjian Zhang, Shu‐Ming Kuo, Zirui Zhang, Yufan Deng, Bohan Yin, Zhaocheng Luo, Ke Xu, Huan Liu   +17 more
wiley   +1 more source

Quadrivalent Formulation of Intranasal Influenza Vaccine M2SR (M2-Deficient Single Replication) Protects against Drifted Influenza A and B Virus Challenge

, 2023
Current influenza vaccines demonstrate low vaccine efficacy, especially when the predominantly circulating strain and vaccine are mismatched. The novel influenza vaccine platform M2- or BM2-deficient single replication (M2SR and BM2SR) has been shown to ...
Gabriele Neumann, Pamuk Bilsel, Michael J. Moser, Yasuko Hatta, Sally Sarawar, Yoshihiro Kawaoka, Lindsay Hill-Batorski   +6 more
core   +1 more source

Causal analysis of trade loss from pathogens: A global study of foot and mouth disease impacts on meat exports

American Journal of Agricultural Economics, EarlyView.
Abstract Our general interest is in global trade loss from livestock pathogens, specifically exports. We adopt a causal inference approach that considers animal disease outbreaks over time as non‐staggered binary treatments with the potential for switching in (infection) and out of treatment (recovery) within the sample period. The outcome evolution of
Mohammad Maksudur Rahman, Thomas L. Marsh   +1 more
wiley   +1 more source

Development of an influenza virus vaccine using the baculovirus-insect cell expression system : implications for pandemic preparedness

, 2009
Key word Influenza, rHA, vaccine, baculovirus, insect cells, production, pandemic preparedness Influenza (or flu) is a highly contagious, acute viral respiratory disease that occurs seasonally in most parts of the world and is caused by influenza ...
Cox, M.M.J.
core  

Multiplex evaluation of influenza neutralizing antibodies with potential applicability to in-field serological studies [PDF]

, 2014
The increased number of outbreaks of H5 and H7 LPAI and HPAI viruses in poultry has major public and animal health implications. The continuous rapid evolution of these subtypes and the emergence of new variants influence the ability to undertake ...
Rafat Rahman (16267478), Calogero Terregino, Temperton, Nigel J., Giovanni Cattoli, Calogero Terregino (4163389), Cattoli, Giovanni, Nigel J. Temperton, Eleonora Molesti, Giovanni Cattoli (52822), Terregino, Calogero, Nigel J Temperton (16261166), Rahman, R., Rafat Rahman, Eleonora Molesti (686215), Temperton, N.J., Rahman, Rafat, Edward Wright, Wright, Edward, Molesti, E., Wright, E., Edward Wright (4468198), Molesti, Eleonora, Terregino, C., Cattoli, G.   +23 more
core   +1 more source

Equine models in translational medicine: A comparative approach to human health

Animal Models and Experimental Medicine, EarlyView.
This diagram summarizes and contrasts rodent and equine models, outlining their strengths, limitations, and applications. Horses offer naturally occurring diseases, genetic and physiological similarities to humans, and suitability for longitudinal and clinical‐scale studies.
Shayan Boozarjomehri Amnieh, Katarzyna Ropka‐Molik   +1 more
wiley   +1 more source

Novel Platforms for the Development of a Universal Influenza Vaccine

Frontiers in Immunology, 2018
Despite advancements in immunotherapeutic approaches, influenza continues to cause severe illness, particularly among immunocompromised individuals, young children, and elderly adults.
Arun Kumar, Arun Kumar, Trine Sundebo Meldgaard, Trine Sundebo Meldgaard, Sylvie Bertholet, Sylvie Bertholet   +5 more
doaj   +1 more source