Results 131 to 140 of about 201,288 (355)
Advanced Science, EarlyView.This study develops lipid nanoparticles (LNPs) combining cationic and ionizable lipids for efficient cytosolic protein delivery. Optimized LNPs deliver functional proteins, including antibodies, enzymes, and Cas9, with high serum stability and albumin‐mediated endocytosis.
Lanfang Ren +6 more
wiley +1 more source
Computer-assisted vaccine design [PDF]
arXiv, 2009 We define a new parameter to quantify the antigenic distance between two H3N2 influenza strains: we use this parameter to measure antigenic distance between circulating H3N2 strains and the closest vaccine component of the influenza vaccine. For the data between 1971 and 2004, the measure of antigenic distance correlates better with efficacy in humans ...
arxiv
Development of efficacious replicon particle vaccines for swine influenza virus [PDF]
, 2011 Swine influenza virus is endemic in the United States swine population. Vaccination of swine against influenza is the most reliable method for decreasing influenza infection in swine.
Vander Veen, Ryan Lee
core +3 more sources
Relapse of polymyalgia rheumatica following adjuvanted influenza vaccine: A case-based review [PDF]
, 2020 Polymyalgia rheumatica (PMR) is the most common inflammatory rheumatological condition affecting individuals aged >50 years. There have been rare reports of PMR and other vasculitides developing within 3 months of influenza vaccination.
Bassendine, Margaret F., Bridge, Simon
core +1 more source
The impact of HPAI trade restrictions on U.S. poultry exports in 2022–23
Applied Economic Perspectives and Policy, EarlyView.Abstract In early 2022, APHIS confirmed a case of highly pathogenic avian influenza (HPAI), signaling the beginning of an extensive HPAI outbreak. Since the start of the outbreak in 2022, more than 105 million birds across commercial and backyard operations in 48 states have been affected. Many countries, including top importers of U.S.
Samantha L. Padilla +2 more
wiley +1 more source
Novel Platforms for the Development of a Universal Influenza Vaccine
Frontiers in Immunology, 2018 Despite advancements in immunotherapeutic approaches, influenza continues to cause severe illness, particularly among immunocompromised individuals, young children, and elderly adults.
Arun Kumar +5 more
doaj +1 more source
Quantifying Influenza Vaccine Efficacy and Antigenic Distance [PDF]
arXiv, 2005 We introduce a new measure of antigenic distance between influenza A vaccine and circulating strains. The measure correlates well with efficacies of the H3N2 influenza A component of the annual vaccine between 1971 and 2004, as do results of a theory of the immune response to influenza following vaccination.
arxiv
Construction and characterization of H5N1-recombinant fowlpox viruses co-expressing host cytokines [PDF]
, 2011 Possessing a large double stranded DNA genome up to 300 kb, fowlpox virus (FWPV) has been developed to express avian influenza virus (AIV) antigens since the late 1980s. A more advanced approach would be to coexpress host cytokines from such recombinants.
Abdul Razak, Mariatulqabtiah +1 more
core +1 more source
Annals of Gastroenterological Surgery, EarlyView.Mortality and anastomotic leakage, two very important complications assessed in SMR, did not worsen during the pandemic compared to prepandemic levels. In Japan, laparoscopic surgery was safe and unaffected by the COVID‐19 pandemic even in 2022, when the epidemic spread.
Masafumi Inomata +14 more
wiley +1 more source