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Engineered Nanoparticulate Vaccines to Combat Recurring and Pandemic Influenza Threats
Recurring seasonal flu epidemics and occasional pandemics are among the most severe threats to public health. Current seasonal influenza vaccines provide limited protection against drifted circulating strains and no protection against influenza pandemics.
Chunhong Dong, Bao-Zhong Wang
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Influenza and Influenza Vaccine: A Review [PDF]
AbstractInfluenza is a highly contagious, deadly virus, killing nearly half a million people yearly worldwide. The classic symptoms of influenza are fever, fatigue, cough, and body aches. In the outpatient setting, diagnosis can be made by clinical presentation with optional confirmatory diagnostic testing.
Cynthia Nypaver+2 more
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Animal Models Utilized for the Development of Influenza Virus Vaccines
Animal models have been an important tool for the development of influenza virus vaccines since the 1940s. Over the past 80 years, influenza virus vaccines have evolved into more complex formulations, including trivalent and quadrivalent inactivated ...
Ericka Kirkpatrick Roubidoux+1 more
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Influenza A viruses pose a substantial threat to the human population whether by purposeful manipulation and release or by the natural process of interspecies transmissions from animal reservoirs. The challenge with preparing for these events with vaccination strategies is that the best forms of protective immunity target the most variable of the viral
A H, Ellebedy, R J, Webby
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Influenza and memory T cells : how to awake the force [PDF]
Annual influenza vaccination is an effective way to prevent human influenza. Current vaccines are mainly focused on eliciting a strain-matched humoral immune response, requiring yearly updates, and do not provide protection for all vaccinated individuals.
Glezen+12 more
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Strategies towards improved influenza vaccines [PDF]
Influenza viruses cause seasonal epidemics and, periodically, unpredictable pandemics, both leading to substantial morbidity and mortality worldwide. Vaccination represents the cornerstone of influenza protection.
Herrera-Rodriquez, José
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Nurses have an important part to play in dispelling myths about influenza vaccination and in actively encouraging older people to attend for vaccination. Irene Schofield discusses the issues.
A, Uma, P, Thirumalaikolundusubramanian
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IntroductionThe haemagglutination inhibition assay (HAI) and the virus microneutralisation assay (MN) are long-established methods for quantifying antibodies against influenza viruses. Despite their widespread use, both assays require standardisation to
Joanna Waldock+22 more
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Evaluation of the preventive effectiveness of influenza vaccines in St. Petersburg
Background. The influenza vaccination coverage has steadily increased in the Russian Federation. The introduction of new domestic influenza vaccines into practice and the study of their effectiveness are of great importance for public health.
M. K. Erofeeva+8 more
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A bivalent live-attenuated influenza vaccine for the control and prevention of H3N8 and H3N2 canine influenza viruses [PDF]
Canine influenza viruses (CIVs) cause a contagious respiratory disease in dogs. CIV subtypes include H3N8, which originated from the transfer of H3N8 equine influenza virus (EIV) to dogs; and the H3N2, which is an avian-origin virus adapted to infect ...
Martínez-Sobrido, Luis+4 more
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