Results 21 to 30 of about 133,411 (313)

INDUCTION OF SECONDARY BACTERIAL PNEUMONIA IN MICE INFECTED WITH PANDEMIC AND LABORATORY STRAINS OF THE H1N1 INFLUENZA VIRUS

Журнал микробиологии, эпидемиологии и иммунобиологии, 2019
Aim. In this study we developed and characterized a mouse model of secondary S. aureus and S. pneumoniae pneumonia following influenza virus infection with H1N1 pandemic and laboratory strains and their reassortment. Materials and methods.
I. A. Leneva, A. Yu. Egorov, I. N. Falynskova, N. R. Маkhmudоvа, N. P. Kartashova, E. A. Glubokova, N. O. Vartanova, A. V. Poddubikov   +7 more
doaj   +1 more source

Recombinant Influenza Vaccines [PDF]

Acta Naturae, 2012
This review covers the problems encountered in the construction and production of new recombinant influenza vaccines. New approaches to the development of influenza vaccines are investigated; they include reverse genetics methods, production of virus-like particles, and DNA- and viral vector-based vaccines.
Sedova, E., Shcherbinin, D., Migunov, A., Smirnov, Iu, Logunov, D., Shmarov, M., Tsybalova, L., Naroditskiĭ, B., Kiselev, O., Gintsburg, A.   +9 more
openaire   +3 more sources

Adjuvantation of Influenza Vaccines to Induce Cross-Protective Immunity

Vaccines, 2021
Influenza poses a huge threat to global public health. Influenza vaccines are the most effective and cost-effective means to control influenza. Current influenza vaccines mainly induce neutralizing antibodies against highly variable globular head of ...
Zhuofan Li, Yiwen Zhao, Yibo Li, Xinyuan Chen   +3 more
doaj   +1 more source

Projected impact of a plant-derived vaccine on the burden of seasonal influenza in Canada

Human Vaccines & Immunotherapeutics, 2021
Objective The analysis estimates projected population outcomes resulting from the introduction of a plant-derived influenza vaccine formulated as quadrivalent virus-like particles (QVLP) in Canada.
Lauren Ramjee, William Lemay, Nesrin Vurgun, Nathalie Charland, Chris T. Bauch, Gokul Raj Pullagura, Sherilyn K. D. Houle, Gabriel Tremblay   +7 more
doaj   +1 more source

Adjuvanted influenza vaccines [PDF]

Human Vaccines & Immunotherapeutics, 2012
The search for adjuvants has been stimulated by the need to ensure greater protection against influenza among subjects who show a reduced immune response to conventional influenza vaccines. Aluminum salts have long been used but are not considered satisfactory.
N. Principi, S. Esposito
openaire   +5 more sources

Cell culture-derived flu vaccine: Present and future

Human Vaccines & Immunotherapeutics, 2018
The benefit of influenza vaccines is difficult to estimate due to the complexity of accurately assessing the burden of influenza. To improve the efficacy of influenza vaccines, vaccine manufacturers have developed quadrivalent influenza vaccine (QIV ...
Alberto Pérez Rubio, Jose María Eiros
doaj   +1 more source

Virus-Vectored Influenza Virus Vaccines

Viruses, 2014
Despite the availability of an inactivated vaccine that has been licensed for >50 years, the influenza virus continues to cause morbidity and mortality worldwide.
Ralph A. Tripp, S. Mark Tompkins
doaj   +1 more source

Impact of the coronavirus disease 2019 epidemic and a free influenza vaccine strategy on the willingness of residents to receive influenza vaccines in Shanghai, China

Human Vaccines & Immunotherapeutics, 2021
The influenza vaccine is not included in China’s national immunization program. Here, we assessed influenza vaccine coverage among Shanghai residents and estimated the impacts of the coronavirus disease 2019 (COVID-19) epidemic and a hypothetical free ...
Yehong Zhou, Jing Tang, Junjie Zhang, Qiangsong Wu   +3 more
doaj   +1 more source

N-glycosylation at the receptor binding site drives differences in receptor binding specificity between influenza B virus lineages

Journal of Virology
Receptor specificity plays a critical role in influenza virus host tropism and pathogenesis. Influenza A and influenza B viruses (FLUAVs and FLUBVs, respectively) utilize N-glycans with terminal sialic acids on glycoproteins decorating the surface of ...
Caroline K. Page, M. H. M. Mubassir, Pradeep Chopra, Lindsey Claire Gay, Ginger Geiger, Sean D. Ray, Justin D. Shepard, Rose J. Miller, Daniel Perez, Justin Bahl, Gerardus Josephus Boons, Stephen Mark Tompkins   +11 more
doaj   +1 more source

A Decade in Review: A Systematic Review of Universal Influenza Vaccines in Clinical Trials during the 2010 Decade

Viruses, 2020
On average, there are 3–5 million severe cases of influenza virus infections globally each year. Seasonal influenza vaccines provide limited protection against divergent influenza strains.
Brigette N. Corder, Brianna L. Bullard, Gregory A. Poland, Eric A. Weaver   +3 more
doaj   +1 more source