Results 71 to 80 of about 201,288 (355)
Influenza: vaccination and treatment [PDF]
European Respiratory Journal, 2001 Few conditions exert such an enormous toll of absenteeism, suffering, medical consultations, hospitalization, death and economic loss as influenza. Patients at high risk of complications and mortality include the elderly and those with pre-existing cardiopulmonary disease.The outbreak in 1997 in Hong Kong, of avian H5N1 influenza in man, which resulted
Stephenson, I, Nicholson, KG
openaire +4 more sources
High Dose Influenza Vaccine Utilization at Inland Hospital in Waterville, Maine [PDF]
, 2018 High-dose influenza vaccines are approved by the FDA for use in adults 65 years and older and have been shown to reduce the morbidity and mortality of influenza.
Klepack, Margaret
core +1 more source
The rationale for quadrivalent influenza vaccines [PDF]
Two antigenically distinct lineages of influenza B viruses have circulated globally since 1985. However, licensed trivalent seasonal influenza vaccines contain antigens from only a single influenza B virus and thus provide limited immunity against ...
Fiore AE +4 more
core +2 more sources
Advanced Healthcare Materials, EarlyView.This research highlights a novel application of protein nanoparticles to effectively modulate the strength, breadth, and bias of an immune response against influenza virus. Nanoparticles precisely co‐delivering antigen (H5) and multiple adjuvants (CpG and FliCc) present a way to improve and direct prophylactic immune responses which can be applicable ...
Aaron Ramirez +6 more
wiley +1 more source
Global Challenges, Volume 7, Issue 1, January 2023., 2023 Combining oncolytic viruses with anti‐checkpoint antibodies such as anti‐PD‐1, anti‐PDL‐1, and anti‐CTLA4 or CAR‐T cells can be effective in cancer therapy in a synergistic fashion. Oncolytic virotherapy induces the expression of PD‐1 and PDL‐1 in the tumor microenvironment components. Virotherapy promotes the infiltration of CD4+ and CD8+ T cells into
Hai Zou, Xiao‐Zhou Mou, Biao Zhu
wiley +1 more source
Modeling vaccination campaigns and the Fall/Winter 2009 activity of the new A(H1N1) influenza in the Northern Hemisphere [PDF]
Emerging Health Threats 2, E11 (2009), 2010 The unfolding of pandemic influenza A(H1N1) for Fall 2009 in the Northern Hemisphere is still uncertain. Plans for vaccination campaigns and vaccine trials are underway, with the first batches expected to be available early October. Several studies point to the possibility of an anticipated pandemic peak that could undermine the effectiveness of ...
arxiv +1 more source
A universal influenza mRNA vaccine candidate boosts T cell responses and reduces zoonotic influenza virus disease in ferrets [PDF]
, 2022 Universal influenza vaccines should protect against continuously evolving and newly emerging influenza viruses. T cells may be an essential target of such vaccines, as they can clear infected cells through recognition of conserved influenza virus ...
Beattie, Mitchell B +14 more
core +2 more sources
Harnessing Nanohybridized Niclosamide for Precision Mpox Therapeutics
Advanced Healthcare Materials, EarlyView.This study investigates the potential of nanohybridized niclosamide as a therapeutic agent for Mpox, focusing on enhanced bioavailability, improved antiviral efficacy, and controlled drug release achieved through nanoengineering. The research emphasizes significant advancements in formulation strategies, mechanistic insights, and therapeutic outcomes ...
N. Sanoj Rejinold +2 more
wiley +1 more source
Novel Influenza Vaccines: From Research and Development (R&D) Challenges to Regulatory Responses
Vaccines, 2023 Influenza vaccines faced significant challenges in achieving sufficient protective efficacy and production efficiency in the past. In recent decades, novel influenza vaccines, characterized by efficient and scalable production, advanced platforms, and ...
Xiangchuan He +3 more
doaj +1 more source
Advances in influenza vaccination [PDF]
F1000Prime Reports, 2014 Influenza virus infections yearly cause high morbidity and mortality burdens in humans, and the development of a new influenza pandemic continues to threaten mankind as a Damoclean sword. Influenza vaccines have been produced by using egg-based virus growth and passaging techniques that were developed more than 60 years ago, following the ...
Albert D. M. E. Osterhaus +2 more
openaire +3 more sources