Results 51 to 60 of about 13,897,575 (306)

An information architecture for validating courseware [PDF]

open access: yes, 2007
Courseware validation should locate Learning Objects inconsistent with the courseware instructional design being used. In order for validation to take place it is necessary to identify the implicit and explicit information needed for validation.
Melia, Mark, Pahl, Claus
core  

The role of histone modifications in transcription regulation upon DNA damage

open access: yesFEBS Letters, EarlyView.
This review discusses the critical role of histone modifications in regulating gene expression during the DNA damage response (DDR). By modulating chromatin structure and recruiting repair factors, these post‐translational modifications fine‐tune transcriptional programmes to maintain genomic stability.
Angelina Job Kolady, Siyao Wang
wiley   +1 more source

Architecture: a guide to finding information [PDF]

open access: yes, 2015
A guide to finding books and journals in the ...
Geoff Morgan
core  

Substrate specificity of Burkholderia pseudomallei multidrug transporters is influenced by the hydrophilic patch in the substrate‐binding pocket

open access: yesFEBS Letters, EarlyView.
Multidrug transporters BpeB and BpeF from the Gram‐negative pathogen Burkholderia pseudomallei have a hydrophilic patch in their substrate‐binding pocket. Drug susceptibility tests and growth curve analyses using an Escherichia coli recombinant expression system revealed that the hydrophilic patches of BpeB and BpeF are involved in the substrate ...
Ui Okada, Satoshi Murakami
wiley   +1 more source

Deep Space Network information system architecture study [PDF]

open access: yes, 1992
The purpose of this article is to describe an architecture for the Deep Space Network (DSN) information system in the years 2000-2010 and to provide guidelines for its evolution during the 1990s.
Atkinson, D. J.   +9 more
core   +1 more source

Function‐driven design of a surrogate interleukin‐2 receptor ligand

open access: yesFEBS Letters, EarlyView.
Interleukin (IL)‐2 signaling can be achieved and precisely fine‐tuned through the affinity, distance, and orientation of the heterodimeric receptors with their ligands. We designed a biased IL‐2 surrogate ligand that selectively promotes effector T and natural killer cell activation and differentiation. Interleukin (IL) receptors play a pivotal role in
Ziwei Tang   +9 more
wiley   +1 more source

Mechanisms of parasite‐mediated disruption of brain vessels

open access: yesFEBS Letters, EarlyView.
Parasites can affect the blood vessels of the brain, often causing serious neurological problems. This review explains how different parasites interact with and disrupt these vessels, what this means for brain health, and why these processes matter. Understanding these mechanisms may help us develop better ways to prevent or treat brain infections in ...
Leonor Loira   +3 more
wiley   +1 more source

Design and Information Architectures for an Unmanned Aerial Vehicle Cooperative Formation Tracking Controller

open access: yesIEEE Access, 2018
This paper addresses a well-documented open problem on the tracking target of the multiple unmanned aerial vehicles (UAVs) subject to the inconsistent of attitude and position in the process of flight.
Jialong Zhang   +3 more
doaj   +1 more source

Guiding InfoGAN with Semi-Supervision

open access: yes, 2017
In this paper we propose a new semi-supervised GAN architecture (ss-InfoGAN) for image synthesis that leverages information from few labels (as little as 0.22%, max.
Aksan, Emre   +2 more
core   +1 more source

BLAST+: architecture and applications

open access: yesBMC Bioinformatics, 2009
BackgroundSequence similarity searching is a very important bioinformatics task. While Basic Local Alignment Search Tool (BLAST) outperforms exact methods through its use of heuristics, the speed of the current BLAST software is suboptimal for very long ...
Christiam Camacho   +6 more
semanticscholar   +1 more source

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