Results 91 to 100 of about 689,793 (290)

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

open access: yesFEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source

Information behaviour of scholars

open access: yesLibellarium : časopis za istraživanja u području informacijskih i srodnih znanosti, 2015
In recent years we have seen intensive debates over the changes in scholarly practice caused by increased accessibility of digital resources and tools. This has caused an evident and rapid trend towards the development of different information behaviours by scholars: what information resources they are using, how and when.
openaire   +3 more sources

Impact of Information Culture and Information Behaviour on Information Quality [PDF]

open access: yes, 2021
<p>Purpose: Although Information Quality (IQ) is a widely discussed topic, people’s influence on the Information Quality remains insufficiently explored. There are many indicators in the academic literature that people play an important role in creating and maintaining information, however, there is a lack of studies investigating how people’s ...
openaire   +1 more source

Transferrin receptor 1‐mediated iron uptake supports thermogenic activation in human cervical‐derived adipocytes

open access: yesFEBS Letters, EarlyView.
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai   +9 more
wiley   +1 more source

[Health information behaviour and health literacy on COVID-19 vaccination of the general population in Germany-findings from the CoSiD study]. [PDF]

open access: yesBundesgesundheitsblatt Gesundheitsforschung Gesundheitsschutz, 2022
Bosle C   +5 more
europepmc   +1 more source

Tau acetylation at K331 has limited impact on tau pathology in vivo

open access: yesFEBS Letters, EarlyView.
We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto   +3 more
wiley   +1 more source

[Risk perception and information behaviour of opinion leaders in the food sector]. [PDF]

open access: yesBundesgesundheitsblatt Gesundheitsforschung Gesundheitsschutz, 2021
Lindemann AK, Jungnickel K, Böl GF.
europepmc   +1 more source

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

open access: yesFEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa   +5 more
wiley   +1 more source

Relevance of Subject Descriptions in an Online Public Access Catalogue

open access: yesKnjižnica, 2012
Purpose:  The aim of the article is to identify the relevance of subject headings in the online library catalogue (OPAC) and to verify the hypothesis that the database structure and the search language is more in favour of natural and technology sciences
Aleš Klemen
doaj   +1 more source

How do personality traits shape information-sharing behaviour in social media? Exploring the mediating effect of generalised trust

open access: yes, 2017
Introduction. Personality and trust have been found to be important precursors of information-sharing behaviour, but little is known about how these factors interact with each other in shaping information-sharing behaviour.
Li, Hongxiu   +4 more
core  

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