Results 111 to 120 of about 18,276,657 (278)

Information seeking behaviour models in Information Retrieval

open access: yes
Information retrieval study can broadly be categorized into two portions; System centered research that centers on the systems perspectives of information retrieval counting retrieval algorithms, indexing, interface design, etc, and user-centered research that centers on the human information behavior and user-centered or cognitive approaches to the ...
openaire   +2 more sources

Salmonella lipopolysaccharide‐containing supported lipid bilayers as platforms to study bacteriophage interactions

open access: yesFEBS Letters, EarlyView.
We present robust protocols for the preparation of supported lipid bilayers (SLBs) incorporating either Salmonella smooth LPS or outer membrane vesicles (OMVs). We use a combination of quartz crystal microbalance with dissipation (QCM‐D) and fluorescence microscopy to both characterize the SLBs of various compositions and to probe their interactions ...
Hudson P. Pace   +6 more
wiley   +1 more source

Microbiome−host proteostasis crosstalk—An emerging perspective on mechanisms and interventions toward healthy longevity

open access: yesFEBS Letters, EarlyView.
Proteostasis and the gut microbiota play a key role in shaping host physiology. Microbiota‐derived metabolites, vitamins, and RNA modulate host proteostasis. Findings from model systems, including C. elegans, indicate microbes can either stabilize or disrupt host proteostasis.
Abhishek Anil Dubey, Maria Ermolaeva
wiley   +1 more source

Leveraging information technology to achieve the IT2000 vision: The case study of an intelligent island

open access: yes, 1998
Behaviour and Information Technology172113 ...
Lim, V.K.G.   +3 more
core   +1 more source

Transdisciplinarity: an imperative for information behaviour research

open access: yesInformation Research: An International Electronic Journal
Introduction. Information behaviour research must be methodologically and conceptually sophisticated to generate knowledge reflecting the complexities of information engagement in people’s lives.
Sarah Polkinghorne   +2 more
doaj  

Design and analysis strategies for robust microbiome ageing research

open access: yesFEBS Letters, EarlyView.
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik   +5 more
wiley   +1 more source

Representational exchange and edgework: towards theorising the coping with fragmentary information

open access: yesInformation Research: An International Electronic Journal
Introduction. People face often situations when the available information is fragmentary and epistemically and ontologically different stemming from multiple incongruous systems of knowledge.
Isto Huvila
doaj  

Information sources of emergency physicians in the Covid-19 crisis

open access: yesInformation Research: An International Electronic Journal
Introduction. Our research is set in the context of the second and third waves of the Covid-19 pandemic within the emergency medical aid service of Paris.
Dijana Lekic-Savatic   +2 more
doaj   +1 more source

Reconstructing enzyme evolution by protein engineering

open access: yesFEBS Letters, EarlyView.
Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler   +2 more
wiley   +1 more source

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