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An investigation of information seeking behaviour of Computer Science and Information Technology undergraduates: a qualitative approach [PDF]

open access: yes, 2009
It is a common fallacy to assume that undergraduates are skilled in finding and evaluating resources for their various learning needs. Information professionals need to find out strategies and courses of action undertaken by undergraduate students in ...
Zainab, A.N.   +3 more
core  

IMPDH inhibition enhances cytarabine efficacy in SAMHD1‐expressing leukaemia cells via guanine nucleotide depletion

open access: yesMolecular Oncology, EarlyView.
Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla   +9 more
wiley   +1 more source

Recent trends in user studies: action research and qualitative methods

open access: yesInformation Research: An International Electronic Journal, 2000
This paper was commissioned by Professor Gernot Wersig of the Freie Universität, Berlin in 1980, as part of his Project, Methodeninstrumentarium zur Benutzforschung in Information und Dokumentation.
T.D. Wilson
doaj  

Navigating subjectivity in causal context: a non-deterministic approach for information behaviour research

open access: yesInformation Research: An International Electronic Journal
Introduction. Information behaviour research often asks causal questions with tools that describe associations. Conventional, regression-based models struggle when constructs are subjective, context-bound, and difficult to estimate. The academic setting
Marek Deja
doaj   +1 more source

Cyber security in the workplace: Understanding and promoting behaviour change

open access: yes, 2013
Cyber security and the role employees play in securing information are major concerns for businesses. The aim of this research is to explore employee security behaviours and design interventions that can motivate behaviour change.
Blythe, John
core  

Keratin 19 as a prognostic marker and contributing factor of metastasis and chemoresistance in high‐grade serous ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch   +13 more
wiley   +1 more source

Information Need and Information Seeking Behaviour

open access: yesTürk Kütüphaneciliği, 1997
Information need is one of the cognitive needs of humankind. Information need causes information seeking behaviour and these concepts complement each other. Information need and information seeking behaviour are effected by many factors. It is necessary to know these factors in establishing the effective information centers and services.
openaire   +1 more source

Self-stigma, alcohol use disorder, information behaviour: a theoretical and conceptual synthesis

open access: yesInformation Research: An International Electronic Journal
Introduction. This study explores how self-stigma influences the information behaviour of individuals living with alcohol use disorder by integrating Goffman’s theory of stigma and impression management with Chatman’s theories of information poverty and
Opeyemi Rachael Oboh
doaj   +1 more source

Somatic mutational landscape in von Hippel–Lindau familial hemangioblastoma

open access: yesMolecular Oncology, EarlyView.
The causes of central nervous system (CNS) hemangioblastoma in Von Hippel–Lindau (vHL) disease are unclear. We used Whole Exome Sequencing (WES) on familial hemangioblastoma to investigate events that underlie tumor development. Our findings suggest that VHL loss creates a permissive environment for tumor formation, while additional alterations ...
Maja Dembic   +5 more
wiley   +1 more source

Beyond information seeking: a general model of information behaviour. [PDF]

open access: yes, 2005
Introduction. The aim of the paper is to review models of information behaviour and to propose new models that extend the concept beyond simply information seeking to consider other modes of behaviour. The models chiefly explored are those of Wilson and
Godbold, N   +2 more
core  

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