Results 61 to 70 of about 1,337,694 (304)
Frontiers in Neurology, 2023 IntroductionMild traumatic brain injury (mTBI) is a common injury that can lead to temporary and, in some cases, life-long disability. Magnetic resonance imaging (MRI) is widely used to diagnose and study brain injuries and diseases, yet mTBI remains ...
Jennie M. Burns +6 more
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Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation
FEBS Letters, EarlyView.Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe +3 more
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, 2021 Physicians rely on online sources of information more so than ever, to find the information they need when treating patients, but little is known about determining the relevance criteria when searching for online sources.
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FEBS Letters, EarlyView.We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee +3 more
wiley +1 more source
FEBS Letters, EarlyView.We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley +1 more source
Kronos scRT: a uniform framework for single-cell replication timing analysis
Nature Communications, 2022 A scalable approach to explore DNA replication in single cells reveals that although aneuploidy does not have a major impact on the pattern of replication, different cell types and sub-populations display distinguished replication paths.
Stefano Gnan +10 more
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Predictive information in Gaussian processes with application to music analysis
, 2013 This is the author's accepted manuscript of this article. The final publication is available at Springer via http://dx.doi.org/10.1007/978-3-642-40020-9.Lecture Notes in Computer ScienceLecture Notes in Computer ScienceWe describe an information ...
Geometric Science of Information +2 more
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Structural insights into an engineered feruloyl esterase with improved MHET degrading properties
FEBS Letters, EarlyView.A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa +5 more
wiley +1 more source
Enterprise Digital Transformation Strategy: The Impact of Digital Platforms
EntropyThe development of the digital economy is a strategic choice for seizing new opportunities in the latest wave of technological revolution and industrial transformation.
Qiong Huang, Yifan Tang
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Hidden information and regularities of information dynamics III
CoRR, 2012 This presentation's Part 3 studies the evolutionary information processes and regularities of evolution dynamics, evaluated by an entropy functional (EF) of a random field (modeled by a diffusion information process) and an informational path functional (IPF) on trajectories of the related dynamic process (Lerner 2012). The integral information measure
openaire +4 more sources