Results 111 to 120 of about 6,011,536 (233)

Molecular bases of circadian magnesium rhythms across eukaryotes

FEBS Letters, EarlyView.
Circadian rhythms in intracellular [Mg2+] exist across eukaryotic kingdoms. Central roles for Mg2+ in metabolism suggest that Mg2+ rhythms could regulate daily cellular energy and metabolism. In this Perspective paper, we propose that ancestral prokaryotic transport proteins could be responsible for mediating Mg2+ rhythms and posit a feedback model ...
Helen K. Feord, Gerben van Ooijen
wiley   +1 more source

TypEx : a type based approach to XML stream querying [PDF]

, 2003
We consider the topic of query evaluation over semistructured information streams, and XML data streams in particular. Streaming evaluation methods are necessarily eventdriven, which is in tension with high-level query models; in general, the more ...
Connor, Richard, Neumüller, Mathias, Russell, George   +2 more
core   +2 more sources

Peptide‐based ligand antagonists block a Vibrio cholerae adhesin

FEBS Letters, EarlyView.
The structure of a peptide‐binding domain of the Vibrio cholerae adhesin FrhA was solved by X‐ray crystallography, revealing how the inhibitory peptide AGYTD binds tightly at its Ca2+‐coordinated pocket. Structure‐guided design incorporating D‐amino acids enhanced binding affinity, providing a foundation for developing anti‐adhesion therapeutics ...
Mingyu Wang, Grace Du, Charity Yongo‐Luwawa, Angelina Lu, Brett Kinrade, Kim Munro, Karl E. Klose, William D. Lubell, Peter Davies, Shuaiqi Guo   +9 more
wiley   +1 more source

DSS for selection and evaluation of information system in SMEs [PDF]

, 2008
In the agri-food sector the SMEs demand more efficiences in marketing, logistics, production planning and controlling, bookkeeping and information services. For these tasks they need correct information in any time and anywhere.
Herdon, Miklós, Rózsa, Tünde
core  

Disordered but rhythmic—the role of intrinsic protein disorder in eukaryotic circadian timing

FEBS Letters, EarlyView.
Unstructured domains known as intrinsically disordered regions (IDRs) are present in nearly every part of the eukaryotic core circadian oscillator. IDRs enable many diverse inter‐ and intramolecular interactions that support clock function. IDR conformations are highly tunable by post‐translational modifications and environmental conditions, which ...
Emery T. Usher, Jacqueline F. Pelham
wiley   +1 more source

Improving Estimates of Land–Atmosphere Coupling Through a Novel Framework of Land Aridity Classification

Geophysical Research Letters
The evapotranspiration (ET) regime is an illustration of the water‐energy interactions at the land surface and is important for regional climate. In this study, we propose a revised framework for land aridity classification based on the ET regime and the
Yufeng Shan, Jiangfeng Wei, Beilei Zan
doaj   +1 more source

Information systems evaluation in context–impact of the corporate level [PDF]

, 2008
The paper presents the results of a doctoral research related to Information Systems evaluation in context. The authors propose changes in the context, the new level of contextual analysis was added: the system context located between the internal and ...
Irani, Z, Piotrowicz, W
core  

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

FEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe, Tanmay Kumar Mohanty, Rashna Bhandari, Dorothea Fiedler   +3 more
wiley   +1 more source

Substrate specificity of Burkholderia pseudomallei multidrug transporters is influenced by the hydrophilic patch in the substrate‐binding pocket

FEBS Letters, EarlyView.
Multidrug transporters BpeB and BpeF from the Gram‐negative pathogen Burkholderia pseudomallei have a hydrophilic patch in their substrate‐binding pocket. Drug susceptibility tests and growth curve analyses using an Escherichia coli recombinant expression system revealed that the hydrophilic patches of BpeB and BpeF are involved in the substrate ...
Ui Okada, Satoshi Murakami
wiley   +1 more source

Four Decades of Scientific Activity in Iran from the Perspective of the Conference Proceedings, Highly Cited and Hot Papers, and Open Access Papers, in the Light of the Law of Economic, Social, and Cultural Development Plan of Iran

Iranian Journal of Information Processing & Management, 2018
This study aims to investigate Iran scientific production pre-revolutionary by 2016 with the emphasis on the conferences proceedings, highly cited and hot papers, and open access papers, in the light of the Law of Economic, Social, and Cultural ...
Mohammad Reza Ghane, Samira Kumarsi
doaj